scholarly journals Characterizing the intersection of Co-occurring risk factors for illicit drug abuse and dependence in a U.S. nationally representative sample

2016 ◽  
Vol 92 ◽  
pp. 118-125 ◽  
Author(s):  
Allison N. Kurti ◽  
Diana R. Keith ◽  
Alyssa Noble ◽  
Jeff S. Priest ◽  
Brian Sprague ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drug Abuse ◽  
Representative Sample ◽  
Illicit Drug ◽  
Illicit Drug Abuse ◽  
Nationally Representative

Illicit drug abuse

2003 ◽  
pp. 383-402
Author(s):  
Cheryl L. Kunis ◽  
Harry J. Ward ◽  
Gerald B. Appel
Keyword(s):  
Drug Abuse ◽  
Illicit Drug ◽  
Illicit Drug Abuse

scholarly journals Psychometric properties of DSM assessments of illicit drug abuse and dependence: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

2007 ◽  
Vol 37 (9) ◽  
pp. 1345-1355 ◽  
Author(s):  
M. T. LYNSKEY ◽  
A. AGRAWAL
Keyword(s):  
Drug Abuse ◽  
Psychometric Properties ◽  
Illicit Drugs ◽  
Illicit Drug ◽  
Item Difficulty ◽  
Descriptive Analysis ◽  
Epidemiological Survey ◽  
Epidemiologic Survey ◽  
Drug Use Disorders ◽  
Illicit Drug Abuse

ABSTRACTBackgroundDSM-IV criteria for illicit drug abuse and dependence are largely based on criteria developed for alcohol use disorders and there is a lack of research evidence on the psychometric properties of these symptoms when applied to illicit drugs.MethodThis study utilizes data on abuse/dependence criteria for cannabis, cocaine, stimulants, sedatives, tranquilizers, opiates, hallucinogens and inhalants from the National Epidemiological Survey on Alcohol and Related Conditions (NESARC, n=43 093). Analyses included factor analysis to explore the dimensionality of illicit drug abuse and dependence criteria, calculation of item difficulty and discrimination within an item response framework and a descriptive analysis of ‘diagnostic orphans’: individuals meeting criteria for 1–2 dependence symptoms but not abuse. Rates of psychiatric disorders were compared across groups.ResultsResults favor a uni-dimensional construct for abuse/dependence on each of the eight drug classes. Factor loadings, item difficulty and discrimination were remarkably consistent across drug categories. For each drug category, between 29% and 51% of all individuals meeting criteria for at least one symptom did not receive a formal diagnosis of either abuse or dependence and were therefore classified as ‘orphans’. Mean rates of disorder in these individuals suggested that illicit drug use disorders may be more adequately described along a spectrum of severity.ConclusionsWhile there were remarkable similarities across categories of illicit drugs, consideration of item difficulty suggested that some alterations to DSM regarding the relevant severity of specific abuse and dependence criteria may be warranted.

Neuropathological Alterations in Illicit Drug Abuse

2012 ◽  
Vol 2 (3) ◽  
pp. 235-241 ◽  
Author(s):  
Andreas Büttner
Keyword(s):  
Drug Abuse ◽  
Illicit Drug ◽  
Illicit Drug Abuse

scholarly journals Dinner consumption and cardiovascular disease risk factors among a nationally representative sample of Iranian adolescents: the CASPIAN-III Study

2019 ◽  
Vol 11 (2) ◽  
pp. 138-146
Author(s):  
Leila Azadbakht ◽  
Fahime Akbari ◽  
Mostafa Qorbani ◽  
Mohammad Esmaeil Motlagh ◽  
Gelayol Ardalan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Representative Sample ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Cluster Sampling ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Nationally Representative

Introduction: This cross-sectional study aimed to assess the association between cardiovascular disease (CVD) risk factors and dinner consumption in a nationally representative sample of Iranian adolescents. Methods: The present study was conducted on 5642 adolescents aged 10-18 years old in 27 provinces in Iran. The subjects were included applying by multistage random cluster sampling. Participants who ate ≥5 dinners during a week were considered as a dinner consumer. Results: Among 5642 subjects, 1412 (25%) did not consume dinner. Dinner consumers were less likely to be overweight or obese (P < 0.001) and abdominally obese (P < 0.001) as well as to have an abnormal level of HDL-C (P = 0.02). Dinner skipper youths had a higher risk for overweight or obesity (odds ratio [OR]: 1.62; 95% CI: 1.39-1.89) and abdominal obesity (OR: 1.59; 95% CI: 1.36-1.85) which remained significant after adjusting confounding factors (P <0001). No relationship was observed between dinner consumption and the rest of the CVD risk factors, neither in crude nor in adjusted models. A higher proportion of dinner-consumer adolescents had no CVD risk factors in comparison to dinner-skipper subjects (31.1% vs. 28%). Conclusion: Eating dinner might be inversely associated with some CVD risk factors among Iranian adolescents. Further prospective studies will need to prove this theory.

Total hip arthroplasty following illicit drug abuse

2018 ◽  
Vol 138 (10) ◽  
pp. 1353-1358 ◽  
Author(s):  
Tim Ramczykowski ◽  
Christiane Kruppa ◽  
Thomas Armin Schildhauer ◽  
Marcel Dudda
Keyword(s):  
Drug Abuse ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Illicit Drug ◽  
Total Hip ◽  
Illicit Drug Abuse

772 Examining sleep difficulties and suicide ideation among those reporting abuse and dependence on illicit drugs and alcohol

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A300-A301
Author(s):  
Rebecca Robbins ◽  
Ralph J DiClimente ◽  
Matthew Weaver ◽  
Catherine Di Gangi ◽  
Isabel Chalem ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Drug Abuse ◽  
Alcohol Use ◽  
Sleep Disturbance ◽  
Suicidal Behavior ◽  
Illicit Drugs ◽  
Illicit Drug ◽  
Drugs And Alcohol ◽  
Illicit Drug Abuse ◽  
The Relationship

Abstract Introduction Sleep disturbance is associated with poor mental health and may contribute to initiating or continuing use/abuse of alcohol and drugs. Using data from a nationwide survey, we examined the relationship between sleep disturbance and suicide behaviors among youth and adults, including those who report drug/alcohol use and abuse. Methods We analyzed data from the 2018 National Survey on Drug Use and Health (NSDUH), an annual survey collecting information about the use of illicit drugs and alcohol among non-institutionalized U.S. youth (age 12–17) and adults (age&gt;17). The 2018 survey included 9,398 youth and 43,026 adult respondents. Depression was assessed in adults with the Kessler-6 and in youth with several questions assessing psychological distress. Those who scored at risk for psychological distress were also asked about sleep disturbance and suicidal behaviors (i.e., ideation, planning, attempt). All were asked to report their drug/alcohol use and/or abuse. Our study population included those who reported psychological distress. We conducted binary logistic regression to examine the relationship between suicidal behavior and sleep disturbance in this population. We also conducted sub-analyses to explore the relationship between suicidal behavior and sleep disturbance among those reporting drug/alcohol use and abuse. Results Youth were 29% male and 71% female, adults were 36% male and 64% female. Adult participants, 39% were 18 to 25, 22% were 26 to 34, and 39% were age 35 and older. Among those with psychological distress, suicidal behavior was more likely among those who reported sleep disturbance (youth: OR=2.7, 95%CI:1.8–4.0; adults: OR=1.3, 95%CI:1.2–1.5). Also, among those with psychological distress, suicidal behavior was more likely among those who reported concomitant sleep disturbance and either alcohol abuse/alcoholism (youth: OR:3.3, 95%CI:1.6–7.0; adults: OR=1.4, 95%CI:1.1–1.7); illicit drug abuse (youth: OR=3.5, 95%CI:1.6–7.4; adults: OR=1.3, 95%CI:1.0–1.6); or alcohol and illicit drug abuse (youth: OR=3.2, 95%CI:1.5–6.9; adults: OR=1.4, 95%CI:1.1–1.7). Conclusion Youth and adults with psychological distress and sleep disturbance are more likely to also report suicidal behaviors. Alcohol and drug use or abuse increase their risk for suicidal behavior compared to those who do not report sleep disturbance. Future work should include examination of causality and of interventions. Support (if any) NIH K24-HL105664, P01-AG009975, T32-HL007901, K01HL150339, 1R56HL151637

scholarly journals Childhood infectious diseases and old age cognitive functioning: a nationally representative sample of community-dwelling older adults

2020 ◽  
pp. 1-8
Author(s):  
A. Rotstein ◽  
S. Z. Levine
Keyword(s):  
Risk Factors ◽  
Older Adults ◽  
Infectious Diseases ◽  
Cognitive Functioning ◽  
Old Age ◽  
Early Life ◽  
Representative Sample ◽  
Community Dwelling ◽  
Sensitivity Analyses ◽  
Nationally Representative

ABSTRACT Background: Cumulative evidence suggests that health-related risk factors during midlife and old-age are associated with cognitive impairment. However, studies are needed to clarify the association between early-life risk factors and impaired cognitive functioning to increment existing knowledge. Objective: To examine the association between childhood infectious diseases and late-life cognitive functioning in a nationally representative sample of older adults. Participants: Eligible respondents were 2994 community-dwelling individuals aged 65–85. Measurements: Cognitive functioning was assessed using the Mini-Mental State Examination (MMSE). Childhood infectious diseases (i.e. chicken pox, measles, and mumps) were self-reported. The study covariates were age, sex, highest educational level achieved, smoking status, body mass index, and depression. The primary statistical analysis examined the association between the number of childhood infectious diseases and total MMSE scores, accounting for all study covariates. Regression models of progressive complexity were examined for parsimony. The robustness of the primary results was tested in 17 sensitivity analyses. Results: The most parsimonious model was a linear adjusted model (Bayesian Information Criterion = 12646.09). Late-life cognitive functioning significantly improved as the number of childhood infectious diseases increased (β = 0.18; 95% CI = 0.11, 0.26; p < 0.001). This effect was not significantly attenuated in all sensitivity analyses. Conclusion: The current study results are consistent with prior ecological findings indicating that some childhood infectious diseases are associated with better cognitive functioning in old-age. This points to an early-life modifiable risk factor associated with older-life cognitive functioning. Our results may reflect selective mortality and/or beneficial effects via hormetic processes.

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