scholarly journals Su1452 – Characterization of Nutritional Status Through Phase Angle and Vector Analysis of Bioelectrical Impedance in Patients with Chronic Pancreatitis and Pancreatic Cancer

2019 ◽  
Vol 156 (6) ◽  
pp. S-556
Author(s):  
Carolina de Luna ◽  
Mariana Gasca Ponce ◽  
Paola Estrada Azarte ◽  
Astrid Ruiz Margáin ◽  
Mario Peláez Luna ◽  
...  
2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Wei Chen ◽  
Shengnan Zhou

Abstract Objectives This study investigated the use of standardized phase angle (SPA), determined by bioelectrical impedance analysis (BIA), as a nutrition status tool and prognostic factor for complications associated with pancreaticoduodenectomy (PD) in pancreatic cancer patients. Methods A cross-sectional study was conducted with 49 participants. All participants were assessed for nutritional risk and nutritional status using Nutritional Risk Screening 2002 (NRS-2002), Subjective Global Assessment (SGA) tools, Global Leadership Initiative on Malnutrition (GLIM) tool and BIA. The Clavien-Dindo classification method for surgical complications was used to identify and classify postoperative complications. Independent-samples T-tests, chi-square tests and Spearman correlation analyses were used to evaluate the association between SPA, nutrition and postoperative complications. Results A total of 49 patients were enrolled, and 20 patients (40%) had postoperative complications. The SPA value for the nourished group was significantly higher than the SPA value for the malnourished group (P = 0.021, 0.019, 0.023). Patients who were below the SPA cut-off values (−1.015, −1.065, and −0.69) were more likely to have postoperative complications (P = 0.009), whereas NRS-2002, SGA, and GLIM scores were not associated with postoperative complications. The SPA value of the group with complications was significantly lower than that of the group without complications (P = 0.004). The SPA threshold value for predicting postoperative complications in pancreatic cancer was −1.095 (AUC 0.737; 95% CI, 0.59, 0.88; P = 0.005). Conclusions The SPA is a prognostic indicator of postoperative complications in pancreatic cancer patients undergoing PD and is an effective tool for assessing nutritional status in pancreatic cancer patients. Funding Sources none. Supporting Tables, Images and/or Graphs


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 484.2-485
Author(s):  
M. Ferro ◽  
S. Charneca ◽  
J. Vasques ◽  
E. Dourado ◽  
C. Sousa Guerreiro ◽  
...  

Background:Rheumatoid arthritis (RA) is a chronic inflammatory disease in which an abnormal body composition was reported to be highly prevalent. (1) Bioelectrical phase angle (PhA) is a measure of the relationship between electric resistance and reactance obtained via bioelectrical impedance analysis (BIA). (2) As an indicator of cellular health, PhA has been described as a predictor of worse clinical outcome and higher mortality in various conditions. (3) Since there is evidence that PhA is related to disease progression and prognosis when considering chronic inflammatory conditions, a lower PhA may also be considered an indicator of a worse prognosis in RA. (1)Objectives:To study the association between PhA, functional status and impact of disease in RA patients.Methods:Observational and cross-sectional study, including 53 patients with RA diagnosis according to the ACR/EULAR 2010 criteria. Each patient demographic data was recorded, and body composition, including PhA by BIA, was obtained. BIA was performed using Bodystat QuadScan 4000 equipment. Functional status and impact of disease were assessed using the Health Assessment Questionnaire (HAQ) and the Rheumatoid Arthritis Impact of Disease (RAID) scores, respectively. PhA was stratified by tertiles (lowest, middle and highest) to create groups of patients. Statistical analysis was performed using student’s t-test (IBM SPSS version 26) for comparisons between groups.Results:A total of 53 patients with RA (81.1% women) with an average age of 62.2 ± 10.2 years were assessed. Mean PhA was 5.8 ± 1.7 °. A PhA lower than 5.2 ° (lowest tertile) was recorded in 17 patients; A PhA ranging from 5.2 ° to 6.0 ° (middle tertile) was observed in 18 patients; A PhA greater than 6.0 ° (highest tertile) was seen in 18 patients. Mean HAQ score was 1.43 ± 0.61 in the lowest tertile, 0.85 ± 0.57 in the middle tertile and 0.67 ± 0.57 in the highest tertile. Mean RAID score was 5.86 ± 1.69 in the lowest tertile, 4.73 ± 2.05 in the middle tertile and 3.00 ± 1.94 in the highest tertile. The statistical analysis showed significant differences in both HAQ and RAID scores between the lowest and the highest tertiles (p=0.001 and p <0.001, respectively). Significant differences were also found between the lowest and the middle tertile for HAQ score (p=0.007) and between the middle and the highest tertile for RAID score (p=0.017).Conclusion:In our cohort a lower PhA was significantly associated with higher HAQ and RAID scores, indicating higher disease impact and higher disability in RA patients with lower PhA. These results support the hypothesis that PhA may be investigated as a possible indicator of disease prognosis in RA.References:[1]Pineda-Juárez JA, Lozada-Mellado M, Ogata-Medel M, Hinojosa-Azaola A, Santillán-Díaz C, Llorente L, et al. Body composition evaluated by body mass index and bioelectrical impedance vector analysis in women with rheumatoid arthritis. Nutrition. 2018;53:49–53.[2]Rinaldi S, Gilliland J, O’Connor C, Chesworth B, Madill J. Is phase angle an appropriate indicator of malnutrition in different disease states? A systematic review. Clin Nutr ESPEN. 2019;29:1–14.[3]Norman K, Stobäus N, Pirlich M, Bosy-Westphal A. Bioelectrical phase angle and impedance vector analysis - Clinical relevance and applicability of impedance parameters. Clin Nutr. 2012;31(6):854–61.Disclosure of Interests:None declared


Author(s):  
Marilia Firmino De Castro Ribeiro ◽  
Juliana Megumi Nisio dos Reis ◽  
Ana Paula Bazanelli

Os parâmetros não tradicionais derivados da bioimpedância elétrica (BIA) como reatância, ângulo de fase e massa celular estão cada vez sendo mais utilizados na prática clínica para auxiliar no diagnóstico nutricional dos pacientes com doença renal crônica e, consequentemente, no prognóstico clínico dessa população. O presente estudo teve por objetivo avaliar a relação dos parâmetros derivados da BIA com o estado nutricional de pacientes em hemodiálise. Estudo transversal, realizado com trinta pacientes adultos de uma clínica de Nefrologia localizada na região metropolitana de São Paulo. Foi utilizada a BIA para avaliar esses parâmetros, assim como para avaliar a composição corporal. A amostra foi constituída por homens e mulheres com média de idade de aproximadamente 56 anos. O ângulo de fase dos pacientes foi de 5,9±1,6 graus e apresentou uma correlação negativa com idade (r= -0,69, p< 0,001) e água corporal extracelular (r= -0,93 p< 0,001). A média de reatância foi de 50,9±16,08 ohms e apresentou correlação negativa com a água extracelular (r= -0,82, p<0,001) e positiva com a massa celular (r=0,51, p<0,004). Em relação ao percentual de massa celular, a média foi de 36,8± 6,1%, sendo que a mesma apresentou uma correlação negativa com a idade (r= -0,66, p< 0,001), gordura corporal (r= -0,73, p< 0,001), água corporal extracelular (r= -0,82, p<0,001).Conclui-se que os parâmetros não tradicionais derivados da BIA apresentaram boa associação com o estado nutricional dos pacientes, podendo dessa forma, serem aliados importantes para obtenção do melhor diagnóstico nutricional e, consequentemente, do prognóstico dos mesmos durante o tratamento dialítico.Palavras-chave: Bioimpedância Elétrica. Estado Nutricional. Diálise.AbstractNon-traditional parameters derived from bioelectrical impedance analysis (BIA) as reactance, phase angle and cell mass are increasingly being used in clinical practice to improve the nutritionalstatus of chronic kidney disease patients andthe clinical outcomes in this population. The present study aimed to evaluate the relationship of parameters derived from the BIA with nutritional status of hemodialysis patients. It was a cross-sectional study with 30 adultspatients of a nephrology clinic in the metropolitan region of São Paulo. BIA was used to evaluate as well as to assess the body composition. The mean age of the patients was approximately 56 years. The phase angle of the patients was 5.9 ± 1.6 degrees and it was negatively correlated with age (r = -0.69, p <0.001) andwith extracellular body water (r = -0.93 p <0.001). The mean reactance was 50.9 ± 16.08 ohms and it showed a negative correlation with the extracellular water (r = -0.82, p <0.001) and positively with the body cell mass (r = 0.51, p <0.004). Regarding to the percentage of body cell mass, the mean was 36.8 ± 6.1%, and it presented a negative correlation with age (r = -0.66, p <0.001), body fat (r = -0.73, p <0.001) and with body water extracellular (r = -0.82, p <0.001). The present study concluded that non-traditional parameters derived from BIA showed a good association with the nutritional status of hemodialysis patients. It is important for getting the best nutritional diagnosis and consequently the prognosis of these patientsduring the dialysis treatment.Keywords: Bioelectrical Impedance. Nutritional Status. Dialysis.


Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4085
Author(s):  
Andrea Da Porto ◽  
Carlo Tascini ◽  
Maddalena Peghin ◽  
Emanuela Sozio ◽  
Gianluca Colussi ◽  
...  

Background: Little is known on the clinical relevance of the nutritional status and body composition of patients hospitalized with SARS-CoV-2 infection. The aim of our study was to assess the prevalence of malnutrition in patients with COVID-19 pneumonia using bioelectrical impedance vector analysis (BIVA), and to evaluate the relationship of their nutritional status with the severity and outcome of disease. Methods: Among 150 consecutive patients who were hospitalized with COVID-19 pneumonia, 37 (24.3%) were classified as malnourished by BIVA, and were followed-up for 60 days from admission. Outcome measures were differences in the need for invasive mechanical ventilation, in-hospital mortality, and the duration of hospital stay in survivors. Results: During 60 days of follow-up, 10 (27%) malnourished patients and 13 (12%) non-malnourished patients required invasive mechanical ventilation (p = 0.023), and 13 (35%) malnourished patients and 9 (8%) non-malnourished patients died (p < 0.001). The average duration of the hospital stay in survivors was longer in patients with malnutrition (18.2 ± 15.7 vs. 13.2 ± 14.8 days, p < 0.001). In survival analyses, mechanical ventilation free (log-rank 7.887, p = 0.050) and overall (log-rank 17.886, p < 0.001) survival were significantly longer in non-malnourished than malnourished patients. The Cox proportional ratio showed that malnutrition was associated with an increased risk of mechanical ventilation (HR 4.375, p = 0.004) and death (HR 4.478, p = 0.004) after adjusting for major confounders such as age, sex, and BMI. Conclusions: Malnutrition diagnosed with BIVA was associated with worse outcomes in hospitalized patients with COVID-19 pneumonia.


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