Personalized finite element model of the knee joint in vivo

2006 ◽  
Vol 39 ◽  
pp. S501
Author(s):  
M. Sangeux ◽  
F. Marin ◽  
F. Charleux ◽  
L. Dürselen ◽  
M.-C. Ho Ba Thoa
Keyword(s):  
Finite Element ◽  
Knee Joint ◽  
Finite Element Model ◽  
Element Model

scholarly journals Using Musculoskeletal Models to Estimate in vivo Total Knee Replacement Kinematics and Loads: Effect of Differences Between Models

2021 ◽  
Vol 9 ◽  
Author(s):  
Cristina Curreli ◽  
Francesca Di Puccio ◽  
Giorgio Davico ◽  
Luca Modenese ◽  
Marco Viceconti
Keyword(s):  
Finite Element ◽  
Knee Joint ◽  
Total Knee Replacement ◽  
Finite Element Model ◽  
Knee Replacement ◽  
Element Model ◽  
Assessment Process ◽  
Grand Challenge ◽  
Total Knee

Total knee replacement (TKR) is one of the most performed orthopedic surgeries to treat knee joint diseases in the elderly population. Although the survivorship of knee implants may extend beyond two decades, the poor outcome rate remains considerable. A recent computational approach used to better understand failure modes and improve TKR outcomes is based on the combination of musculoskeletal (MSK) and finite element models. This combined multiscale modeling approach is a promising strategy in the field of computational biomechanics; however, some critical aspects need to be investigated. In particular, the identification and quantification of the uncertainties related to the boundary conditions used as inputs to the finite element model due to a different definition of the MSK model are crucial. Therefore, the aim of this study is to investigate this problem, which is relevant for the model credibility assessment process. Three different generic MSK models available in the OpenSim platform were used to simulate gait, based on the experimental data from the fifth edition of the “Grand Challenge Competitions to Predict in vivo Knee Loads.” The outputs of the MSK analyses were compared in terms of relative kinematics of the knee implant components and joint reaction (JR) forces and moments acting on the tibial insert. Additionally, the estimated knee JRs were compared with those measured by the instrumented knee implant so that the “global goodness of fit” was quantified for each model. Our results indicated that the different kinematic definitions of the knee joint and the muscle model implemented in the different MSK models influenced both the motion and the load history of the artificial joint. This study demonstrates the importance of examining the influence of the model assumptions on the output results and represents the first step for future studies that will investigate how the uncertainties in the MSK models propagate on disease-specific finite element model results.

A Three-Dimensional Dynamic Finite Element Model of the Prosthetic Knee Joint: Simulation of Joint Laxity and Kinematics

2005 ◽  
Vol 219 (6) ◽  
pp. 415-424 ◽  
Author(s):  
M Barink ◽  
A van Kampen ◽  
M de Waal Malefijt ◽  
N Verdonschot
Keyword(s):  
Finite Element ◽  
Knee Joint ◽  
Finite Element Model ◽  
Mathematical Formulation ◽  
Three Dimensional ◽  
Element Model ◽  
Joint Kinematics ◽  
Published Data ◽  
Dynamic Finite Element ◽  
Flexion Extension

For testing purposes of prostheses at a preclinical stage, it is very valuable to have a generic modelling tool, which can be used to optimize implant features and to avoid poor designs being launched on to the market. The modelling tool should be fast, efficient, and multipurpose in nature; a finite element model is well suited to the purpose. The question posed in this study was whether it was possible to develop a mathematically fast and stable dynamic finite element model of a knee joint after total knee arthroplasty that would predict data comparable with published data in terms of (a) laxities and ligament behaviour, and (b) joint kinematics. The soft tissue structures were modelled using a relatively simple, but very stable, composite model consisting of a band reinforced with fibres. Ligament recruitment and balancing was tested with laxity simulations. The tibial and patellar kinematics were simulated during flexion-extension. An implicit mathematical formulation was used. Joint kinematics, joint laxities, and ligament recruitment patterns were predicted realistically. The kinematics were very reproducible and stable during consecutive flexion-extension cycles. Hence, the model is suitable for the evaluation of prosthesis design, prosthesis alignment, ligament behaviour, and surgical parameters with respect to the biomechanical behaviour of the knee.

A 3D Biphasic Finite Element Model of the Human Knee Joint for the Study of Tibiofemoral Contact and Fluid Pressurization

2013 ◽  
Author(s):  
Hongqiang Guo ◽  
Suzanne A. Maher ◽  
Robert L. Spilker
Keyword(s):  
Finite Element ◽  
Fluid Flow ◽  
Knee Joint ◽  
Contact Problem ◽  
Finite Element Model ◽  
Soft Tissues ◽  
Fluid Pressure ◽  
Element Model ◽  
Human Knee Joint ◽  
Biphasic Finite Element

Biphasic theory which considers soft tissue, such as articular cartilage and meniscus, as a combination of a solid and a fluid phase has been widely used to model their biomechanical behavior [1]. Though fluid flow plays an important role in the load-carrying ability of soft tissues, most finite element models of the knee joint consider cartilage and the meniscus as solid. This simplification is due to the fact that biphasic contact is complicated to model. Beside the continuity conditions for displacement and traction that a single-phase contact problem consists of, there are two additional continuity conditions in the biphasic contact problem for relative fluid flow and fluid pressure [2]. The problem becomes even more complex when a joint is being modeled. The knee joint, for example, has multiple contact pairs which make the biphasic finite element model of this joint far more complex. Several biphasic models of the knee have been developed [3–9], yet simplifications were included in these models: (1) the 3D geometry of the knee was represented by a 2D axisymmetric geometry [3, 5, 6, 9]; (2) no fluid flow was allowed between contact surfaces of the soft tissues [4, 8] which is inconsistent with the equation of mass conservation across the contact interface [10]; (3) zero fluid pressure boundary conditions were inaccurately applied around the contact area [7].

Inverse Estimation of the In Vivo Mechanical Properties of the Human Cornea

2000 ◽  
Author(s):  
Shou-sung Chang ◽  
Peter M. Pinsky
Keyword(s):  
Mechanical Properties ◽  
Finite Element ◽  
Finite Element Model ◽  
Element Model ◽  
Human Cornea ◽  
Corneal Tissue ◽  
Shear Moduli ◽  
Inverse Estimation ◽  
Nonlinear Finite Element Model

Abstract Various forms of refractive surgery for vision correction have come into clinical practice in which the corneal tissue is either incised, removed, added to, or redistributed. The outcomes of these procedures must be to a large extent determined by the intrinsic mechanical properties of the major structural layer of the cornea, the stroma1. If these mechanical properties, principally the Young’s modulus and shear modulus, are established for the human cornea, it will be possible to include them in a finite element model of the stroma that can help predict the outcome of keratorefractive procedures. In this study an opto-mechanical testing device was developed to measure the contour of a cornea deformed in situ by a mechanical probe. A nonlinear finite element model of the cornea was then constructed to simulate the experiment for use in inverse estimation of the in vivo Young’s and shear moduli of an individual eye.

A Finite Element Model of a Rotating Platform Total Knee Employing a Nonlinear, Dual-Surface-Contact Formulation

2000 ◽  
Author(s):  
Jason K. Otto ◽  
Thomas D. Brown ◽  
John J. Callaghan
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Mobile Bearing ◽  
Element Model ◽  
Polyethylene Insert ◽  
Rotating Platform ◽  
Mobile Interface ◽  
Surface Contact ◽  
Total Knee

Abstract Mobile bearing total knees avoid the conformity/constraint tradeoff of fixed bearing total knees. However, a recent in vivo fluoroscopic study of the most popular mobile bearing total knee in the U.S. showed that bearing motion failed to occur in half of the patients observed. A nonlinear, multiple-surface contact finite element model of a rotating platform total knee was therefore developed to investigate the interaction at the “mobile” interface (contact between the tibial tray and the polyethylene insert) under physiologically relevant loads (1–4 BW) and rotations (10° endorotation). The data showed that there was a linear relationship between axial load and the torque resisting endorotation. Peak contact stresses were located on the medial and lateral peripheral edges of the polyethylene insert. All relative rotation occurred at the “mobile” interface. The same trends were seen in a complementary experimental study of the same components, suggesting that the finite element model is valid under these loading conditions.

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