Validation of a capillary isoelectric focusing method for the recombinant monoclonal antibody C2B8

1998 ◽  
Vol 800 (2) ◽  
pp. 355-367 ◽  
Author(s):  
G Hunt ◽  
T Hotaling ◽  
A.B Chen
Keyword(s):  
Monoclonal Antibody ◽  
Isoelectric Focusing ◽  
Capillary Isoelectric Focusing ◽  
Recombinant Monoclonal Antibody

An improved capillary isoelectric focusing-mass spectrometry method for high-resolution characterization of monoclonal antibody charge variants

2022 ◽  
Author(s):  
Tian Xu ◽  
Linjie Han ◽  
Alayna M. George Thompson ◽  
Liangliang Sun
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
High Resolution ◽  
Isoelectric Focusing ◽  
Capillary Isoelectric Focusing ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Charge Variants

Routine and high-resolution characterization of monoclonal antibody (mAb) charge variants is vital for controlling mAb quality as therapeutics. Capillary isoelectric focusing-mass spectrometry (cIEF-MS) has emerged as a powerful tool for...

scholarly journals Evaluation of the V8 E-Class, a Novel Automated Capillary Isoelectric Focusing Instrument for Hemoglobinopathy Screening

2016 ◽  
Vol 146 (3) ◽  
pp. 361-368 ◽  
Author(s):  
Toon Schiemsky ◽  
Caroline Brusselmans ◽  
Elke Nackers ◽  
Pieter Vermeersch ◽  
Koen Poesen ◽  
...  
Keyword(s):  
Isoelectric Focusing ◽  
Capillary Isoelectric Focusing ◽  
Class A
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