Characterization of a new hereditary thrombopathy in a closed colony of Wistar rats

1996 ◽  
Vol 128 (6) ◽  
pp. 601-611 ◽  
Author(s):  
Scott V. Smith ◽  
Lawrence Lumeng ◽  
Marjorie S. Read ◽  
Leslie V. Parise ◽  
Robert L. Reddick ◽  
...  
Keyword(s):  
2018 ◽  
Vol 320 ◽  
pp. 15-18
Author(s):  
Francisco Nachón-García ◽  
Gabriela Hurtado-Alvarado ◽  
Mario E. Acosta-Hernández ◽  
Carolina Peña-Escudero ◽  
Sergio Priego-Fernández ◽  
...  

2015 ◽  
Vol 10 (4) ◽  
pp. 1483-1488 ◽  
Author(s):  
HOU-PAN SONG ◽  
XIN LI ◽  
RONG YU ◽  
GUANG ZENG ◽  
ZHEN-YI YUAN ◽  
...  

Author(s):  
Djallel Eddine Houari ADLI ◽  
Mostapha BRAHMI ◽  
Kaddour ZIANI ◽  
Wafaa ARABI ◽  
Khaled KAHLOULA ◽  
...  

The present study was carried out in order to evaluate, on the one hand, the modifications induced by manganese chloride according to a neurobehavioral, biochemical and histological approach in developing Wistar rats and, on the other hand, to test the effectiveness of Foeniculum vulgare (fennel) essential oil (FEO) in restoring or not the harmful effects of manganese chloride (MnCl2). The characterization of this essential oil by gas chromatography showed that the major component is E-anethole (34.7907%). The administration of FEO corrected the depressive state, anxiety and locomotor hypoactivity respectively observed in rats exposed to MnCl2, thus, the FEO restored the activity of the various antioxidant enzymes with a clear improvement of the cerebral tissue architecture in intoxicated rats treated with FEO. In conclusion, the FEO has a beneficial effect on the nervous system of rats intoxicated with MnCl2 which justifies the importance of this oil in traditional medicine.


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 3099-3103
Author(s):  
Gomathi Priyadharsini T ◽  
Kavimani M ◽  
Sathiya Narayana Murthy S ◽  
Prabhu K ◽  
Arudyuti Chowdhury

The nephroprotective prospective of Premna tomentosa extract against Alcohol induced nephrotoxicity in rats was investigated in the present study. The characterization of ethanol extract of Premna tomentosa (EPT) was performed using standard phytochemical analysis. Male albino wistar rats 36 in numbers were divided into 6 groups including control, negative control, positive control and various doses of EPT Treated groups; Nephrotoxicity was induced by alcohol (1ml/100gm b.wt) in animals. Rats intoxicated with Alcohol were fed with 500, 750 mg/kg dose of EPT and Liv 52 (1ml/100gm b.wt) for 60 days. Results show that EPT (500mg/kg b.wt) had a significant effect against alcohol induced nephrotoxicity in rats than EPT (750mg/kg b.wt) in blood parameters and consonantly good histopathological changes in kidney. The deleterious histopathological alterations in kidney associated with glomerular and tubular changes in alcohol intoxicated rats was evident. This result shows Premna tomentosa may be used as supplementary drug for alcoholics.


2011 ◽  
Vol 44 (2) ◽  
pp. 43-50 ◽  
Author(s):  
Anabelle Silva Cornachione ◽  
Priscila Cação Oliveira Benedi ◽  
Juliana Cristina Polizello ◽  
Leonardo César Carvalho ◽  
Ana Cláudia Mattiello-Sverzut
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