Nitric oxide contributes to myocardial energy metabolism: Effects of aging and hypertension

2001 ◽  
Vol 33 (6) ◽  
pp. A36
Author(s):  
Y. Fukuhiro ◽  
S. Mochimki ◽  
H. Nakamoto ◽  
Y. Ogasawara ◽  
T. Tanemoto
Keyword(s):  
Nitric Oxide ◽  
Energy Metabolism ◽  
Myocardial Energy Metabolism ◽  
Effects Of Aging

scholarly journals Cardiac Metabolism in Sepsis

Metabolites ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 846
Author(s):  
Satoshi Kawaguchi ◽  
Motoi Okada
Keyword(s):  
Nitric Oxide ◽  
Energy Metabolism ◽  
Cardiac Dysfunction ◽  
Adrenergic Receptors ◽  
Therapeutic Strategy ◽  
Cardiac Metabolism ◽  
Metabolic Abnormalities ◽  
Myocardial Energy Metabolism ◽  
Β Adrenergic Receptors ◽  
Chemical Mediators

The mechanism of sepsis-induced cardiac dysfunction is believed to be different from that of myocardial ischemia. In sepsis, chemical mediators, such as endotoxins, cytokines, and nitric oxide, cause metabolic abnormalities, mitochondrial dysfunction, and downregulation of β-adrenergic receptors. These factors inhibit the production of ATP, essential for myocardial energy metabolism, resulting in cardiac dysfunction. This review focuses on the metabolic changes in sepsis, particularly in the heart. In addition to managing inflammation, interventions focusing on metabolism may be a new therapeutic strategy for cardiac dysfunction due to sepsis.

Nitric oxide: a new player in the modulation of energy metabolism

2000 ◽  
Vol 24 (S4) ◽  
pp. S36-S40 ◽  
Author(s):  
S Kapur ◽  
F Picard ◽  
M Perreault ◽  
Y Deshaies ◽  
A Marette
Keyword(s):  
Nitric Oxide ◽  
Energy Metabolism
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