scholarly journals The metabolic consequences of a “washed” cardiopulmonary bypass pump-priming fluid in children undergoing cardiac operations

1990 ◽  
Vol 100 (4) ◽  
pp. 528-537 ◽  
Author(s):  
P.D. Ridley ◽  
J.M. Ratcliffe ◽  
K.G.M.M. Alberti ◽  
M.J. Elliott
Keyword(s):  
Cardiopulmonary Bypass ◽  
Cardiac Operations

Results with continuous cardiopulmonary bypass for the bidirectional cavopulmonary anastomosis

2008 ◽  
Vol 18 (2) ◽  
pp. 147-152 ◽  
Author(s):  
Robroy H. MacIver ◽  
Robert D. Stewart ◽  
Carl L. Backer ◽  
Constantine Mavroudis
Keyword(s):  
Cardiopulmonary Bypass ◽  
Circulatory Arrest ◽  
Deep Hypothermic Circulatory Arrest ◽  
Moderate Hypothermia ◽  
Absorbable Sutures ◽  
Cavopulmonary Anastomosis ◽  
Postoperative Length ◽  
The Mean ◽  
Bidirectional Cavopulmonary Anastomosis ◽  
Cardiac Operations

AbstractObjectiveSome centres have proposed creating the bidirectional cavopulmonary anastomosis without cardiopulmonary bypass, while others continue to use deep hypothermic circulatory arrest. The purpose of this review is to evaluate the results of using continuous cardiopulmonary bypass with moderate hypothermia, perhaps the most commonly used of the three techniques for this procedure.MethodsBetween 1990 and 2005, 114 patients, having a mean age of 1.58 years, with a median age of 8 months, and ranging from 3 months to 16 years, underwent creation of either a unilateral cavopulmonary anastomosis, in 94 cases, or bilateral anastomoses in 20 cases. All had continuous cardiopulmonary bypass with moderate hypothermia at 32 degrees Celsius, with 24 also having aortic cross-clamping with cardioplegia for simultaneous intracardiac procedures. Interrupted absorbable sutures were used to create the anastomosis in 105 patients.ResultsPerioperative mortality was 5%, with 6 of the patients dying. The mean period of cardiopulmonary bypass for an isolated anastomosis was 91 minutes, with a range from 44 to 160 minutes. In 10 patients (8.8%), it was necessary to place a graft to augment the anastomosis. The average postoperative length of stay was 7.9 days for those undergoing an isolated unilateral anastomosis, and 16.4 days for patients undergoing combined cardiac operations. We have now created the Fontan circulation in 79 of the patients, at an average interval from the bidirectional cavopulmonary anastomosis of 2.1 plus or minus 1.14 years. In 76 patients, we performed postoperative angiograms, and none revealed any stenoses.ConclusionsThe bidirectional cavopulmonary anastomosis can be performed successfully with continuous cardiopulmonary bypass and moderate hypothermia with a beating heart, avoiding circulatory arrest. The use of interrupted and absorbable sutures was not associated with any late anastomotic stenosis.

scholarly journals VITAMIN D STATUS IN NEONATES UNDERGOING CARDIAC OPERATIONS: RELATIONSHIP TO CARDIOPULMONARY BYPASS AND OUTCOMES

2012 ◽  
Vol 59 (13) ◽  
pp. E739
Author(s):  
Eric Matthew Graham ◽  
Sarah N. Taylor ◽  
Sinai Zyblewski ◽  
Bethany Wolf ◽  
Scott Bradley ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cardiopulmonary Bypass ◽  
Vitamin D Status ◽  
Cardiac Operations

Utilising cardiopulmonary bypass for cancer surgery. Malignancy-induced protein C deficiency and thrombophilia

Perfusion ◽  
2007 ◽  
Vol 22 (6) ◽  
pp. 381-383
Author(s):  
C Marshall
Keyword(s):  
Cardiopulmonary Bypass ◽  
Cancer Patients ◽  
Protein C ◽  
Thromboembolic Event ◽  
Cancer Surgery ◽  
Protein C Deficiency ◽  
Post Surgery ◽  
Increased Risk ◽  
Cardiac Surgeon ◽  
Cardiac Operations

Cardiopulmonary bypass has evolved over the last 30 years. It is an important tool for the cardiac surgeon today and also has applications in non-cardiac operations such as surgery to extract tumours. Such patients undergoing surgery for cancer may be at an increased risk of a thromboembolic event post surgery, due to disturbances in the normal clotting pathway leading to hypercoagulability. One such disturbance is malignancy-induced Protein C deficiency. A deficiency of Protein C can cause hypercoagulabitity. Recent studies have examined cardiopulmonary bypass and inherited Protein C deficiency. However, surgery for cancer patients with a malignancy-induced Protein C deficiency involving cardiopulmonary bypass has not been reported. Surgery using CPB in these patients may result in increased morbidity and mortality. The objective of this article is to review the literature in order to discuss the occurrence, the aetiology and possible management of cancer patients with malignancy-induced Protein C deficiencies that require cardiopulmonary bypass for their surgery.

Effect of subzero-balanced ultrafiltration on postoperative outcome of patients after cardiopulmonary bypass

Perfusion ◽  
2009 ◽  
Vol 24 (6) ◽  
pp. 401-408 ◽  
Author(s):  
Tao Zhang ◽  
Chang-qing Gao ◽  
Jia-chun Li ◽  
Jia-li Wang ◽  
Li-bing Li ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Treatment Group ◽  
Hospital Mortality ◽  
Group Versus ◽  
Postoperative Outcome ◽  
Postoperative Recovery ◽  
Postoperative Outcomes ◽  
Control Group ◽  
Mortality And Morbidity ◽  
Cardiac Operations

Objective: To evaluate the effect of a new ultrafiltration technique — subzero-balanced ultrafiltration technique — on early postoperative outcomes of adult patients undergoing cardiac operations with cardiopulmonary bypass. Methods: A total of 120 patients who required cardiopulmonary bypass for cardiac surgery were randomized into two groups, 60 in each group. Patients in the treatment group received subzero-balanced ultrafiltration during cardiopulmonary bypass, while patients in the control group received routine cardiopulmonary bypass. Postoperative outcomes, including hospital mortality and morbidity of the two groups, were analyzed. Results: Hospital mortality was 0% (0 of 60) in the treatment group versus 1.8% (1 of 60) in the control group (P=1.000). Total hospital complications was lower in the treated patients (11 of 60 [18.3%] versus 22 of 60 [36.7%], P=0.025). Duration of intubation time was shorter and transfusion volume within 24 hours postoperatively was less in patients having received subzero-balanced ultrafiltration during cardiopulmonary bypass (14.35 ± 1.66 versus 18.64 ± 1.57 h, P=0.036 and 1.54 ± 1.56 versus 3.64 ± 2.67 U/patient, P=0.032). Length of stay on the intensive care unit, duration of hospital stay, need for infusion of inotropic agent and drainage volumes within 24 h postoperatively between the two groups were comparable. Conclusions: Subzero-balanced ultrafiltration during cardiopulmonary bypass can effectively decrease the patients’ hospital morbidity and the volume of blood transfusion: it also may promote early postoperative recovery of patients. Routine application of subzero-balanced ultrafiltration during adult cardiac operations should not be necessary, but the technique should be compared to other techniques, e.g. MUF, in further studies.

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