Early complications of long-term respiratory support

AbstractIntroduction:Bony canalplasty is a common otological procedure performed to widen a narrow ear canal. The aim of this report is to describe two unusual patients who presented with a canal wall cholesteatoma many years after bony canalplasty.Cases:Two patients, aged 28 and 52 years, are presented. Both underwent canalplasty, 14 and 17 years before re-presenting with cholesteatoma evident through posterior canal wall defects. Both patients underwent exploration of the mastoid cavities and cartilage reconstruction of the canal walls. There was no recurrence at 24 and three month follow-up examinations (variously), hearing was preserved in both cases, and the patients suffered no early complications.Conclusions:The most frequent long-term complication of canalplasty is re-stenosis of the external auditory canal. The importance of sealing any inadvertently opened mastoid air cells, in order to avoid the late complication reported, is emphasised.

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Respiratory outcomes in children with congenital myotonic dystrophy

Journal of Pediatric Rehabilitation Medicine ◽

10.3233/prm-200726 ◽

2021 ◽

pp. 1-5

Author(s):

Jaclyn C. Omura ◽

Maida Chen ◽

Miriam Haviland ◽

Susan Apkon

Keyword(s):

Respiratory Distress ◽

Myotonic Dystrophy ◽

Invasive Mechanical Ventilation ◽

Retrospective Chart Review ◽

Mortality Rates ◽

Respiratory Support ◽

Non Invasive ◽

Congenital Myotonic Dystrophy ◽

Respiratory Outcomes

PURPOSE: Congenital myotonic dystrophy (CDM) results in hypotonia and acute respiratory distress at birth. Previous studies show that prolonged periods of intubation (>4 weeks) correlate with increased mortality rates. The objective is to describe the use and duration of respiratory support in newborns with CDM and how these relate to mortality. METHODS: A retrospective chart review was performed at a tertiary pediatric hospital among children with confirmed diagnosis of CDM. The main outcome measures were: mortality, duration of invasive mechanical ventilation (IMV) and non-invasive partial pressure ventilation (NIPPV), along with long-term use of respiratory support and equipment. RESULTS: A total of 18 subjects met inclusion criteria, 83%.f which had documented respiratory distress at birth, 39%.equired NIPPV, and 50%.equired intubation in the neonatal period. The earliest NIPPV was initiated at day one of life, and the latest extubation to NIPPV was at 17 days of life. CONCLUSION: This cohort required IMV for shorter periods with earlier transitions to NIPPV which suggests a possible change in practice and earlier transition to NIPPV recently. Further data are needed to determine if there is a possible correlation between the need for NIPPV/IMV and mortality rates.

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The Interval Between Staged Bilateral Total Knee Arthroplasties Does Not Affect Early Complications of the Second Knee or Long-term Function of the First and Second Knees

10.21203/rs.3.rs-1069755/v1 ◽

2021 ◽

Author(s):

Guangqian Shang ◽

Shuai Xiang ◽

Jianjun Guo ◽

Feng Ji ◽

Shuai Yang ◽

...

Keyword(s):

Complication Rate ◽

Optimal Time ◽

Time Interval ◽

Early Complications ◽

Postoperative Function ◽

Term Function ◽

Significant Difference ◽

Patient Reported ◽

Total Knee

Abstract Background: This study explored the optimal time interval between staged bilateral total knee arthroplasty (BTKA) to minimise early complications of the second TKA and maximise long-term function of the first and second knees.Methods: We retrospectively reviewed 266 patients who underwent staged BTKA between 2010 and 2015. Groups 1–4 had time intervals between BTKAs of 1–6, 6–12, 12–18, and 18–24 months, respectively. Demographics, postoperative complications within 90 days of the second TKA, Knee Society Score (KSS), and Western Ontario and McMaster Universities Arthritis Index (WOMAC) score were compared among the groups.Results: In total, 54, 96, 75, and 41 patients were assigned to groups 1–4, respectively. Although group 1 had the highest overall complication rate (11.11%), there was no significant difference in the complication rate among the four groups. Also, no significant differences were found among the four groups in functional and patient-reported outcomes, in either the first or second knee at 5 years postoperatively, including KSS-knee, KSS-function, WOMAC-pain, WOMAC-stiffness, and WOMAC-physical function. The interval between BTKA did not influence complications or the function of the second knee. The TKA type (posterior-stabilised vs. medial-pivot) and age did not correlate significantly with any scores.Conclusions: There was no group difference in early complications of the second TKA, and postoperative function was equivalent between the two knees and did not vary by the interval between surgeries. Our results can help surgeons discuss the timing of the second TKA with patients, which should be based on their own preferences. If patients cannot tolerate severe symptoms in the contralateral knee after the first TKA, the second TKA should be performed as early as possible.

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Regrowth of the adenoids after adenoidectomy down to the pharyngobasilar fascial surface

The Journal of Laryngology & Otology ◽

10.1017/s0022215115001437 ◽

2015 ◽

Vol 129 (7) ◽

pp. 662-665 ◽

Cited By ~ 5

Author(s):

L Wei ◽

M Wang ◽

N Hua ◽

K Tong ◽

L Zhai ◽

...

Keyword(s):

Surgical Technique ◽

Blood Loss ◽

Success Rate ◽

Operation Time ◽

Early Complications ◽

Estimated Blood Loss ◽

Endoscopic Guidance ◽

Pharyngobasilar Fascia

AbstractObjectives:This study aimed to explore adenoid regrowth after transoral power-assisted adenoidectomy down to the pharyngobasilar fascial surface.Methods:Transoral adenoidectomy down to the pharyngobasilar fascia surface was performed on 39 patients under endoscopic guidance, using a power-assisted system. The operation time, amount of blood loss and iatrogenic injury, presence of complications, and success and regrowth rates were recorded to assess the feasibility, safety and effectiveness of our surgical technique.Results:In this adenoidectomy procedure, the pharyngobasilar fascia was left intact. The estimated blood loss was 5–50 ml (mean 15 ml), and the success rate was 97.3 per cent. Early complications occurred in 2.3 per cent of patients, while no long-term complications occurred in the cohort. No regrowth was found in the follow-up assessments, which were performed for 18–36 months after surgery.Conclusion:Adenoid regrowth was rare after adenoidectomy down to the pharyngobasilar fascial surface. The pharyngobasilar fascia can therefore be considered a surgical boundary for adenoidectomy.

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Acute promyelocytic leukemia: preventing early complications and late toxicities

Hematology ◽

10.1182/asheducation-2016.1.10 ◽

2016 ◽

Vol 2016 (1) ◽

pp. 10-15 ◽

Cited By ~ 20

Author(s):

Sameem Abedin ◽

Jessica K. Altman

Keyword(s):

Acute Myeloid Leukemia ◽

Acute Promyelocytic Leukemia ◽

Myeloid Leukemia ◽

Early Death ◽

Promyelocytic Leukemia ◽

Early Complications ◽

Younger Patients ◽

Success Stories ◽

Acute Myeloid

Abstract Acute promyelocytic leukemia (APL) is a unique subtype of acute myeloid leukemia (AML), which presents with a distinct coagulopathy. Therapeutic advances have made APL one of the true success stories in oncology, transforming this once lethal disease into the most curable form of AML. For many patients, cure will now be achieved without the use of chemotherapy. It is hoped that limiting chemotherapy will reduce mortality even further, particularly among more vulnerable older adults whose survival lagged behind that of younger patients. It should be noted that early death persists in patients with APL and continues to negatively affect survival. Further, among survivors treated with chemotherapy or even arsenic trioxide (ATO), there remains the potential for long-term toxicities that must be monitored. Understanding the management of these issues is an important complement to ensure maximal survival for patients with APL.

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Early complications, long-term adverse events, and quality of life after duodenal switch and gastric bypass in a matched national cohort

Surgery for Obesity and Related Diseases ◽

10.1016/j.soard.2020.02.001 ◽

2020 ◽

Vol 16 (5) ◽

pp. 614-619 ◽

Cited By ~ 6

Author(s):

Martin L. Skogar ◽

Magnus Sundbom

Keyword(s):

Quality Of Life ◽

Gastric Bypass ◽

Adverse Events ◽

Duodenal Switch ◽

Early Complications ◽

National Cohort

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Fluoroscopically Guided Peritoneal Dialysis Catheter Placement: Long-Term Results from a Single Center

Peritoneal Dialysis International ◽

10.1177/089686080802800212 ◽

2008 ◽

Vol 28 (2) ◽

pp. 163-169 ◽

Cited By ~ 45

Author(s):

Ju-Young Moon ◽

Sebin Song ◽

Kyung-Hwan Jung ◽

Mina Park ◽

Sang-Ho Lee ◽

...

Keyword(s):

Peritoneal Dialysis ◽

Catheter Removal ◽

Long Term Results ◽

Significant Prognostic Factor ◽

Peritoneal Dialysis Catheter ◽

Early Complications ◽

Catheter Survival ◽

Minimal Invasiveness ◽

Relative Safety

Objective Despite percutaneous fluoroscopy ensuring appropriate placement of peritoneal dialysis (PD) catheters, the efficacy of this method is not well known. Therefore, we evaluated our long-term experience with fluoroscopy-assisted placement of PD catheters. Patients and Methods We retrospectively reviewed 134 PD catheters in 114 PD patients that were treated in the PD center of a university-based hospital. We evaluated complications related to PD catheters, causes for catheter removal, and catheter survival. We used the multivariate Cox proportional hazard model to identify independent factors related to PD catheter survival. Results Early complications related to insertion included 1 case of pericatheter bleeding; there were no placement failures. Early complications occurred in 8.5% of patients. Most late complications were migration and leakage, which occurred in 10.4% and 9.7% of patients respectively. The most common cause for catheter removal was intractable and recurrent peritonitis. The 12- and 24-month survival rates of the catheters were 80.0% and 74.9%. The most significant prognostic factor of percutaneous fluoroscopy-assisted PD catheter survival was late leakage ( p < 0.01). Conclusions In addition to the advantages of simplicity, minimal invasiveness, and relative safety, the survival rate of PD catheters placed using the percutaneous fluoroscopy-assisted method was comparable to that of more invasive methods. Percutaneous fluoroscopy-assisted placement of PD catheters should be considered when available, and may be preferred to other placement methods.

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