A COMPARISON OF AMERICAN JOINT COMMITTEE ON CANCER PATHOLOGIC STAGE T3a VERSUS T3b UROTHELIAL CANCER: ANALYSIS OF PATIENT OUTCOMES

2008 ◽  
Vol 179 (4S) ◽  
pp. 546-546
Author(s):  
Kelly J Boudreaux ◽  
Sam S Chang ◽  
William T Lowrance ◽  
Jon A Rumohr ◽  
Daniel A Barocas ◽  
...  
2008 ◽  
Vol 179 (4S) ◽  
pp. 579-579
Author(s):  
Kelly J Boudreaux ◽  
Peter E Clark ◽  
William T Lowrance ◽  
Jon A Rumohr ◽  
Daniel A Barocas ◽  
...  

Cancer ◽  
2009 ◽  
Vol 115 (4) ◽  
pp. 770-775 ◽  
Author(s):  
Kelly J. Boudreaux ◽  
Sam S. Chang ◽  
William T. Lowrance ◽  
Jon A. Rumohr ◽  
Daniel A. Barocas ◽  
...  

2009 ◽  
Vol 181 (2) ◽  
pp. 540-546 ◽  
Author(s):  
Kelly J. Boudreaux ◽  
Peter E. Clark ◽  
William T. Lowrance ◽  
Jon A. Rumohr ◽  
Daniel A. Barocas ◽  
...  

2013 ◽  
Vol 7 (9-10) ◽  
pp. 312 ◽  
Author(s):  
Jo-An Seah ◽  
Srikala Sridhar ◽  
Lori Wood ◽  
Normand Blais ◽  
Scott North ◽  
...  

Neoadjuvant chemotherapy (NC) improves overall survival inpatients with resectable muscle-invasive urothelial cancer of the bladder (MIBC). However uptake of NC in Canada is disappointingly low. Following a detailed literature review and in consultation with urologic oncology, the Canadian Association of Genitourinary Medical Oncologists (CAGMO) has developed a consensus statement for the use of NC in MIBC. Our primary goal is to increase the uptake of NC for MIBC in Canada and improve patient outcomes.


2019 ◽  
Vol 27 (S2) ◽  
Author(s):  
D. E. Meyers ◽  
S. Banerji

Immune checkpoint inhibitor–based therapies that target ctla-4, PD-1, or the PD-1 ligand PD-L1 have received approval in Canada and many parts of the world for the treatment of melanoma, renal cell cancer, urothelial cancer, classical Hodgkin lymphoma, and non-small-cell lung cancer. However only a small proportion of patients derive long-term clinical benefit. Here, we describe the biomarkers associated with the complex relationship between tumour-related immune stimulus, T cell–mediated immune response, and immune modulation of the microenvironment that can help to predict improved patient outcomes.


2021 ◽  
Vol 9 (7) ◽  
pp. e002552
Author(s):  
Matthew D Galsky ◽  
Arjun V Balar ◽  
Peter C Black ◽  
Matthew T Campbell ◽  
Gail S Dykstra ◽  
...  

A number of immunotherapies have been developed and adopted for the treatment of urothelial cancer (encompassing cancers arising from the bladder, urethra, or renal pelvis). For these immunotherapies to positively impact patient outcomes, optimal selection of agents and treatment scheduling, especially in conjunction with existing treatment paradigms, is paramount. Immunotherapies also warrant specific and unique considerations regarding patient management, emphasizing both the prompt identification and treatment of potential toxicities. In order to address these issues, the Society for Immunotherapy of Cancer (SITC) convened a panel of experts in the field of immunotherapy for urothelial cancer. The expert panel developed this clinical practice guideline (CPG) to inform healthcare professionals on important aspects of immunotherapeutic treatment for urothelial cancer, including diagnostic testing, treatment planning, immune-related adverse events (irAEs), and patient quality of life (QOL) considerations. The evidence- and consensus-based recommendations in this CPG are intended to give guidance to cancer care providers treating patients with urothelial cancer.


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