The Diagnosis and Treatment of Trauma to the Central Nervous System

1956 ◽  
Vol 40 (5) ◽  
pp. 1369-1384
Author(s):  
Richard C. Schneider
2020 ◽  
Author(s):  
Vladimir V. Belopasov ◽  
Ekaterina M. Samoilova ◽  
Vladimir P. Baklaushev

Based on the available publications, the article systematizes the forms of damage to the central nervous system in СOVID-19patients. Along with a description of clinical manifestations, pathogenesis, methods of laboratory, instrumental and radiological diagnosis with the discussion of the nosological forms. An interdisciplinary approach and international cooperation are required to study the problems pathogenesis, course, outcomes, and the development of new methods of diagnosis and treatment.


2005 ◽  
Vol 129 (12) ◽  
pp. 1635-1652 ◽  
Author(s):  
Suzanne Z. Powell

Abstract Context.—Intraoperative evaluation of lesions in the central nervous system requires the correlation of clinical, radiologic, and histologic data and knowledge of clinicopathologic entities and their common locations. Advances in neuroimaging during the last 20 years have revolutionized the diagnosis and treatment of central nervous system diseases. The diagnosis and treatment of patients have improved because of these changes and have allowed access to regions that were previously inaccessible. These new approaches have placed the pathologist in a key role in the diagnosis and treatment of patients with central nervous system lesions. Assessment of the adequacy of the material, particularly for stereotactic biopsies, is necessary, and a combination of cytologic imprint preparations and frozen sections are often used. This review discusses many of the issues involved in intraoperative consultation and provides a simplified approach to the differential diagnosis of a variety of central nervous system lesions that may be encountered intraoperatively. Objective.—To provide guidelines for and address potential pitfalls in the intraoperative management of the central nervous system. Data Sources.—Author's experience and pertinent literature. Conclusions.—Careful assessment of the gross specimen coupled with prudent use of frozen sections and cytologic imprint preparations is pivotal to reducing intraoperative error rates and preventing needless anxiety for the patient.


2009 ◽  
Vol 59 (3) ◽  
pp. 167-187 ◽  
Author(s):  
Guy Thwaites ◽  
Martin Fisher ◽  
Cheryl Hemingway ◽  
Geoff Scott ◽  
Tom Solomon ◽  
...  

2018 ◽  
Vol 101 (3) ◽  
pp. 273-292
Author(s):  
Stephanie M. Curley ◽  
Nathaniel C. Cady

Delivery of imaging agents and pharmaceutical payloads to the central nervous system (CNS) is essential for efficient diagnosis and treatment of brain diseases. However, therapeutic delivery is often restricted by the blood-brain barrier (BBB), which prevents transport of clinical compounds to their region of interest. This review discusses the methods that have been used to avoid or overcome this barrier, presenting the use of biologically-derived nanomaterial systems as an efficient strategy for the diagnosis and treatment of CNS diseases. Biological nanomaterials have many advantages over synthetic systems, including being biodegradable, biocompatible, easily surface functionalised for conjugation of targeting moieties, and are often able to self-assemble. These abilities are discussed in relation to various systems, including liposomes, dendrimers, and viral nanoparticles.


1988 ◽  
Vol 68 (1) ◽  
pp. 145-148 ◽  
Author(s):  
Paul L. Penar ◽  
Jung Kim ◽  
Douglas Chyatte ◽  
James K. Sabshin

✓ Infection by Cryptococcus neoformans, a budding nonmycelial yeast, involves the central nervous system in 70% of patients at the time of diagnosis. Meningitis and meningoencephalitis are common manifestations of infection; solid granulomas occur but are unusual, and intraventricular granulomas are distinctly rare. Two cases of intraventricular cryptococcal granuloma are reported. The diagnosis and treatment of mass lesions due to cryptococcal infection are discussed, with special reference to intraventricular granulomas.


Sign in / Sign up

Export Citation Format

Share Document