A randomized controlled trial on the efficacy of alternative treatment regimens for uncomplicated falciparum malaria in a multidrug-resistant falciparum area of Bangladesh—narrowing the options for the National Malaria Control Programme?

2001 ◽  
Vol 95 (6) ◽  
pp. 661-667 ◽  
Author(s):  
M.Ridwanur Rahman ◽  
Dulal Chandra Paul ◽  
Md Rashid ◽  
Ajoy Ghosh ◽  
A.Mannan Bangali ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Malaria Control ◽  
Alternative Treatment ◽  
Controlled Trial ◽  
National Malaria Control Programme ◽  
Multidrug Resistant ◽  
Control Programme ◽  
Malaria Control Programme ◽  
Treatment Regimens ◽  
Randomized Controlled

Randomized Observational Studies on the Economics of Therapies – Biometrical Experience of Two Trials

1998 ◽  
Vol 37 (01) ◽  
pp. 53-58 ◽  
Author(s):  
J. Högel ◽  
A. C. Rodloff ◽  
G. Büchele ◽  
W. Gaus
Keyword(s):  
Randomized Controlled Trial ◽  
Observational Studies ◽  
Controlled Trial ◽  
Innovative Therapy ◽  
Treatment Regimens ◽  
Randomized Controlled ◽  
Long Run ◽  
Low Costs ◽  
The Cost ◽  
Economic Studies

Abstract:Economic studies in medicine are intended to investigate costs, associated with a particular problem dealing with the indication, diagnosis or therapy, for instance, whether the high costs involved in a highly intensive or innovative therapy could be balanced by the eventual savings made, due to the shorter periods of treatment. In such situations a randomized controlled trial is necessary to find out which therapy or which therapeutical strategy is least expensive in the long run. Economic studies do, however, present some specific problems. Making a list of all the cost-relevant treatment items can be very laborious, but the use of flat rates and lump sums alone cannot lead to a complete cost analysis. Often, costs between hospitals vary more than between treatment regimens.Early and sudden deaths incur low costs and may bias the results. Furthermore, costs are distributed with a long and heavy upper tail incltJding extreme outliers. This does, in fact, complicate the estimation of the sample size. In this article, these problems are outlined and, with the help ofthe data obtained from two randomized economic trials in health care, solutions are proposed and discussed.

Balneotherapy is an alternative treatment for mastalgia; a randomized controlled trial

2018 ◽  
Vol 19 ◽  
pp. 100-104 ◽  
Author(s):  
Aysun Genç ◽  
Suleyman Utku Çelik ◽  
Deniz Evcik ◽  
Ebru Düşünceli Atman ◽  
Atilla Halil Elhan ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Alternative Treatment ◽  
Controlled Trial ◽  
Randomized Controlled

scholarly journals Long-term Transmission Patterns and Public Health Policies Leading to Malaria Elimination in Panamá

2020 ◽  
Author(s):  
Lisbeth Hurtado ◽  
Alberto Cumbreras ◽  
Chystrie Rigg ◽  
Milixa Perea ◽  
Ana María Santamaría ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Retrospective Analysis ◽  
Malaria Control ◽  
Time Series Data ◽  
Southern Oscillation ◽  
National Malaria Control Programme ◽  
Control Programme ◽  
Series Data ◽  
Malaria Control Programme

Abstract Background: The present study provides a countrywide perspective of the malaria situation in Panama over a long-term framework, with the purpose of identifying historical malaria resurgence events and their potential causes.Methods: A descriptive-ecological study was conducted by analyzing demographic and epidemiological annual malaria time series data in Panamá (1884 – 2019) using several data sources. Malaria intensity indicators were calculated during the study period. We also analyze the effects of El Niño Southern Oscillation on malaria transmission using a retrospective analysis of malaria cases between 1957 and 2019.Results: Several factors were identified responsible for malaria resurgence in Panama, mostly related with Malaria Control Programme weakening. During the past 20 years (2000 – 2019) malaria has progressively increased its prevalence within indigenous settlements, with a predominance of male cases and a high proportion (15% of total cases) in children less than 5 years old. During this period a significant and increasing proportion of the P. falciparum total cases were imported. Our retrospective analysis (1957 - 2019) evidenced that ENSO has a significant impact on malaria transmission dynamics in Panama.Conclusions: Data analysis confirmed that although authorities have been successful in focalizing malaria transmission in the country, there are still neglected issues to be solved and important intercultural barriers that need to be addressed in order to achieve elimination of the disease by 2022. This information will be useful for targeting strategies by the National Malaria Control Programme.

scholarly journals An Overview of the Malaria Control Programme in Zambia

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Emmanuel Chanda ◽  
Mulakwa Kamuliwo ◽  
Richard W. Steketee ◽  
Michael B. Macdonald ◽  
Olusegun Babaniyi ◽  
...  
Keyword(s):  
Malaria Control ◽  
National Development ◽  
National Malaria Control Programme ◽  
Universal Coverage ◽  
Control Programme ◽  
Malaria Control Programme ◽  
Evidence Based ◽  
Malaria Surveillance ◽  
High Coverage ◽  
The Government

The Zambian national malaria control programme has made great progress in the fight against Malaria. The country has solid, consistent, and coordinated policies, strategies, and guidelines for malaria control, with government prioritizing malaria in both the National Health Strategic Plan and the National Development Plan. This has translated into high coverage of proven and effective key preventive, curative, and supportive interventions with concomitant marked reduction in both malaria cases and deaths. The achievements attained can be attributed to increased advocacy, communication and behaviour changes, efficient partnership coordination including strong community engagement, increased financial resources, and evidence-based deployment of key technical interventions in accordance with the national malaria control programme policy and strategic direction. The three-ones strategy has been key for increased and successful public-private sector partner coordination, strengthening, and mobilization. However, maintaining the momentum and the gains is critical as the programme strives to achieve universal coverage of evidence-based and proven interventions. The malaria control programme’s focus is to maintain the accomplishments, by mobilizing more resources and partners, increasing the government funding towards malaria control, scaling up and directing interventions based on epidemiological evidence, and strengthen active malaria surveillance and response to reduce transmission and to begin considering elimination.

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