The effect of low molecular weight chelators on iron chelation and free radical generation as studied by ESR measurement

Chemosphere ◽  
2002 ◽  
Vol 48 (1) ◽  
pp. 21-28 ◽  
Author(s):  
Yuhui Qian ◽  
Barry Goodell ◽  
Christopher C. Felix
Keyword(s):  
Molecular Weight ◽  
Free Radical ◽  
Iron Chelation ◽  
Low Molecular Weight ◽  
Free Radical Generation ◽  
Radical Generation

The effect of vitamin C and iron on dopamine-mediated free radical generation: implications to Parkinson's disease

2018 ◽  
Vol 47 (12) ◽  
pp. 4059-4069 ◽  
Author(s):  
Yingying Sun ◽  
An Ninh Pham ◽  
T. David Waite
Keyword(s):  
Oxidative Stress ◽  
Parkinson’S Disease ◽  
Free Radical ◽  
Combination Therapy ◽  
Vitamin C ◽  
Iron Chelation ◽  
Iron Chelator ◽  
Promising Direction ◽  
Free Radical Generation ◽  
Radical Generation

While the application of Asc alone may aggravate the progression of PD in view of the possible peroxidation of Asc bound Fe(ii), a combination therapy of Asc and strong clinically appropriate iron chelator would appear to be a promising direction for the treatment of PD as a result of the enhanced iron chelation and attenuation in oxidative stress and toxicity induced by DA derived quinones.

Myocardial haem proteins, oxidant stress & free radical generation

1990 ◽  
Vol 9 ◽  
pp. 182
Author(s):  
Catherine Rice-Evans ◽  
Jeremy J.O. Turner ◽  
Emma Newman ◽  
Michael J. Davies
Keyword(s):  
Free Radical ◽  
Oxidant Stress ◽  
Free Radical Generation ◽  
Radical Generation ◽  
Haem Proteins
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