Cost-effectiveness of simvastatin in people at different levels of vascular disease risk: economic analysis of a randomised trial in 20 536 individuals

The Lancet ◽  
2005 ◽  
Vol 365 (9473) ◽  
pp. 1779-1785 ◽  
2014 ◽  
Vol 11 (2) ◽  
pp. 142-148 ◽  
Author(s):  
Claudia Ferreira ◽  
Maria Carvalho ◽  
Helton Reis ◽  
Karina Gomes ◽  
Marinez Sousa ◽  
...  

2004 ◽  
Vol 185 (2) ◽  
pp. 102-107 ◽  
Author(s):  
Jae-Min Kim ◽  
Robert Stewart ◽  
Il-Seon Shin ◽  
Jin-Sang Yoon

BackgroundAssociations between vascular risk factors and late-life depression are controversial.AimsTo investigate the association between measures of vascular disease/ risk and depression and confounding and effect modification by APOE genotype and cognitive function.MethodIn a Korean community population aged 65+ (n=732), diagnosis of depression (Geriatric Mental State Schedule) and information on vascular status, disability, APOE genotype and cognitive function were obtained.ResultsPrevious stroke and lower high-density lipoprotein cholesterol level (but neither hypertension nor diabetes) were significantly associated with depression (independently of disability and cognitive function). These associations were stronger in participants with borderline cognitive impairment, although not to a significant extent.ConclusionsExcept for previous stroke and an atherogenic lipid profile, associations between depression and other common risk factors for cerebrovascular disease were not evident.


PEDIATRICS ◽  
1983 ◽  
Vol 71 (3) ◽  
pp. 466-466
Author(s):  
DOUGLAS RICHARDSON

To the Editor.— I was delighted to see Donn's letter about the cost effectiveness of home management of bronchopulmonary dysplasia.1 Such contributions are vital in helping to curb the rapidly rising costs of neonatal intensive care. However, his economic analysis is flawed. By tacit assumption, he omits any consideration of the opportunity costs to the parents. To omit this presumes that the parents' time is worth little or nothing, as we often seem to indicate by the long patient waiting times in our offices.


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