ALKALOIDS OF VINCA ROSEA IN LEUKÆMIA

Vinblastine(Vb) or vincristine, alkaloid derived from Vinca rosea is known for its antimitotic activity by regrouping of microtubules into paracrystalline form within the cells. A rapid purification method of vinblastine-induced microtubular paracrystals(PC) has provided us with a fresh and pure microtubular material demonstrating the presence of a labile ATPase associated with the PC. The present report is concerned with the fine structure of purified microtubules of mammalian cultured cells.Confluent monolayer cultures of L cells were incubated for 20hrs with 10-5 M Vb (donated from Shionogi Seiyaku & Co., Osaka, Japan).

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COMPARATIVE BIOLOGICAL EVALUATION OF SIX ENDOPHYTIC FUNGI ISOLATED FROM VINCA ROSEA LEAVES

Al-Azhar Journal of Pharmaceutical Sciences ◽

10.21608/ajps.2019.64113 ◽

2019 ◽

Vol 59 (1) ◽

pp. 137-151

Author(s):

Ahmed Metwaly

Keyword(s):

Endophytic Fungi ◽

Biological Evaluation ◽

Vinca Rosea

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Larvicidal Effect of Vinca Fruit Extract (Vinca rosea) Against Aedes aegypti Larvae and Secondary Metabolites Profile by Thin Layer Chromatography

Biology Medicine & Natural Product Chemistry ◽

10.14421/biomedich.2014.31.31-33 ◽

2014 ◽

Vol 3 (1) ◽

pp. 31

Author(s):

Rahmawati Ekaputri ◽

Sudarsono Sudarsono ◽

Budi Mulyaningsih

Keyword(s):

Aedes Aegypti ◽

Thin Layer ◽

Thin Layer Chromatography ◽

Larvicidal Activity ◽

Larval Mortality ◽

Probit Analysis ◽

Mosquito Vector ◽

Fruit Extract ◽

Vinca Rosea ◽

Layer Chromatography

Background: Vinca rosea is known contain alkaloids, it was usually used to treat various diseases. Alkaloids from Vinca leaves are also already known have larvicidal activity. Based on this toxicological activity, the fruit of Vinca rosea was selected to investigation its larvicidal activity against the 3rd instar larvae of the mosquito vector of dengue haemorrhagic fever (DHF) Aedes aegypti. Five concentrations of Vinca fruit extract were tested against the 3rd instar Aedes aegypti larvae. The different larval mortality percentages were recorded after 24 hours. Lethal concentration (LC50 anf LC90) of Vinca fruit extract were calculated using Probit analysis. Phytochemical compounds of ethanolic extract also investigated using Thin layer Chromatography (TLC). LC50 and LC90 values of fruit extract were 2.987 mg/ml and 32.861 mg/ml. Alkaloids were detected in extract.

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N6-(Δ2-isopentenyl)adenosine from crown gall tumor tissue of Vinca rosea

Phytochemistry ◽

10.1016/s0031-9422(00)88938-4 ◽

1976 ◽

Vol 15 (10) ◽

pp. 1565 ◽

Cited By ~ 35

Author(s):

Chong-Maw Chen ◽

Richard L. Eckert ◽

James D. McChesney

Keyword(s):

Crown Gall ◽

Tumor Tissue ◽

Crown Gall Tumor ◽

Vinca Rosea ◽

Isopentenyl Adenosine

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ANTI-CANCER ALKALOIDS OF VINCA ROSEA

Pharmacology of Oriental Plants ◽

10.1016/b978-0-08-010809-4.50011-4 ◽

1965 ◽

pp. 61-78 ◽

Cited By ~ 1

Author(s):

R.L. NOBLE

Keyword(s):

Vinca Rosea ◽

Anti Cancer

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Trace Elements in Two Varities of Indigenous Medicinal Plant Catharanthus roseus (Vinca rosea)

Journal of Medical Sciences(Faisalabad) ◽

10.3923/jms.2001.74.77 ◽

2001 ◽

Vol 1 (2) ◽

pp. 74-77

Author(s):

Sahito S. R. ◽

T.G. Kazi ◽

G. H. Kazi ◽

M. A. Jakhrani ◽

M .S. Shaikh

Keyword(s):

Trace Elements ◽

Medicinal Plant ◽

Catharanthus Roseus ◽

Vinca Rosea

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Vinca rosea Linn.

10.1007/springerreference_69681 ◽

2011 ◽

Keyword(s):

Vinca Rosea

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A YELLOWS-TYPE VIRUS OF ALSIKE CLOVER IN ALBERTA

Canadian Journal of Botany ◽

10.1139/b65-058 ◽

1965 ◽

Vol 43 (5) ◽

pp. 527-536 ◽

Cited By ~ 16

Author(s):

L. N. Chiykowski

Keyword(s):

Daucus Carota ◽

Type Virus ◽

Nicotiana Rustica ◽

Aster Yellows ◽

Daucus Carota L ◽

Vinca Rosea ◽

Clover Phyllody

A yellows-type virus was isolated from naturally infected alsike clover, Trifolium hybridum L., from Alberta by means of the six-spotted leafhopper, Macrosteles fascifrons (Stål), and transmitted to T. hybridum, Callistephus chinensis Nees, Vinca rosea L., Daucus carota L., and Nicotiana rustica L. Attempts to isolate the virus with Scaphytopius acutus (Say) were unsuccessful. On the basis of symptomatology and vector–virus relationships it is concluded that this virus is distinct from the clover phyllody virus and known strains of the aster yellows virus. The name, clover proliferation virus, is proposed. Symptoms produced on hosts are illustrated and discussed.

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