Cueing unavoidable physical but not emotional stress increases long-term behavioural effects in rats

2002 ◽  
Vol 134 (1-2) ◽  
pp. 393-401 ◽  
Author(s):  
Femke T.A Pijlman ◽  
Gerrit Wolterink ◽  
Jan M van Ree
Keyword(s):  
Emotional Stress ◽  
Behavioural Effects

scholarly journals The long-term bio-behavioural effects of juvenile sildenafil treatment in Sprague-Dawley versus Flinders Sensitive Line rats

2021 ◽  
pp. 1-20
Author(s):  
Juandré Lambertus Bernardus Saayman ◽  
Stephanus Frederik Steyn ◽  
Christiaan Beyers Brink
Keyword(s):  
Sprague Dawley ◽  
Long Term Effects ◽  
Bdnf Level ◽  
Treatment Groups ◽  
Sd Rats ◽  
Behavioural Effects ◽  
Sensitive Line ◽  
Level Analysis ◽  
Flinders Sensitive Line

Abstract Objective: To investigate the long-term effects of juvenile sub-chronic sildenafil (SIL) treatment on the depressive-like behaviour and hippocampal brain-derived neurotrophic factor (BDNF) levels of adult Sprague-Dawley (SD) versus Flinders Sensitive Line (FSL) rats. Methods: SD and FSL rats were divided into pre-pubertal and pubertal groups, whereafter 14-day saline or SIL treatment was initiated. Pre-pubertal and pubertal rats were treated from postnatal day 21 (PND21) and PND35, respectively. The open field and forced swim tests (FST) were performed on PND60, followed by hippocampal BDNF level analysis one day later. Results: FSL rats displayed greater immobility in the FST compared to SD rats (p < 0.0001), which was reduced by SIL (p < 0.0001), regardless of treatment period. Hippocampal BDNF levels were unaltered by SIL in all treatment groups (p > 0.05). Conclusion: Juvenile sub-chronic SIL treatment reduces the risk of depressive-like behaviour manifesting during young adulthood in genetically susceptible rats.

Behavioural effects of long-term administration of fencamfamine: Neurochemical implications

1987 ◽  
Vol 18 (4) ◽  
pp. 347-349 ◽  
Author(s):  
Cleopatra S. Planeta ◽  
Cristoforo Scavone ◽  
Roberto De Lucia ◽  
Moacyr L. Aizenstein
Keyword(s):  
Behavioural Effects ◽  
Term Administration

scholarly journals Behavioural effects of temperature on ectothermic animals: unifying thermal physiology and behavioural plasticity

2016 ◽  
Author(s):  
Paul K. Abram ◽  
Guy Boivin ◽  
Joffrey Moiroux ◽  
Jacques Brodeur
Keyword(s):  
Future Research ◽  
Behavioural Plasticity ◽  
Behavioural Ecology ◽  
Behavioural Thermoregulation ◽  
Unified Framework ◽  
Behavioural Changes ◽  
Behavioural Effects ◽  
Effects Of Temperature ◽  
Kinetic Effects

AbstractTemperature imposes significant constraints on ectothermic animals, and these organisms have evolved numerous adaptations to respond to these constraints. While the impacts of temperature on the physiology of ectotherms have been extensively studied, there are currently no frameworks available that outline the multiple and often simultaneous pathways by which temperature can affect behaviour. Drawing from the literature on insects, we propose a unified framework that should apply to all ectothermic animals, generalizing temperature's behavioural effects into (1) Kinetic effects, resulting from temperature's bottom-up constraining influence on metabolism and neurophysiology over a range of timescales (from short-to long-term), and (2) Integrated effects, where the top-down integration of thermal information intentionally initiates or modifies a behaviour (behavioural thermoregulation, thermal orientation, thermosensory behavioural adjustments). We discuss the difficulty in distinguishing adaptive behavioural changes due to temperature from behavioural changes that are the products of constraints, and propose two complementary approaches to help make this distinction and class behaviours according to our framework: (i) behavioural kinetic null modeling and (ii) behavioural ecology experiments using temperature-insensitive mutants. Our framework should help to guide future research on the complex relationship between temperature and behaviour in ectothermic animals.

scholarly journals The role of the accessory pathway radiofrequency catheter ablation in the secondary prevention of the malignant tachyarrhythmias in patients with Wolff-Parkinson-White syndrome

2010 ◽  
Vol 67 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Nebojsa Mujovic ◽  
Miodrag Grujic ◽  
Stevan Mrdja ◽  
Aleksandar Kocijancic ◽  
Tatjana Potpara ◽  
...  
Keyword(s):  
Physical Activity ◽  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Secondary Prevention ◽  
Emotional Stress ◽  
Drug Administration ◽  
Clinical Manifestation ◽  
Accessory Pathway

Background/Aim. The occurrence of atrial fibrillation (AF) in the presence of an accessory pathway (AP) that conducts rapidly is potentially lethal because the rapid ventricular response may lead to ventricular fibrillation (VF). The aim of the study was to determine long-term efficacy of AP catheter-ablation using radiofrequency (RF) current in secondary prevention of VF in WPW patients. Methods. Study included a total of 192 symptomatic WPW patients who underwent RF catheter-ablation of AP in our institution from 1994 to 2007 and were available for clinical follow-up for more than 3 months after procedure. Results. Before ablation, VF was recorded in total of 27 patients (14.1%). In 14 of patients (51.9%) VF was the first clinical manifestation of WPW syndrome. A total of 35 VF episodes were identified in 27 patients. The occurrence of VF was preceded by physical activity or emotional stress in 17.1% of cases, by alcohol abuse in 2.9% and by inappropriate intravenous drug administration in 28.6%. In addition, no clear precipitating factor was identified in 40% of VF cases, while informations about activities preceding 11.4% of VF episodes were not available. The follow-up of 5.7 ? 3.3 years was obtained in all of 27 VF patients. Of the 20 patients who underwent successful AP ablation, all were alive, without syncope or ventricular tachyarrhythmias during long-term follow-up. In 4 of 7 unsuccessfully treated patients, recurrence of supraventricular tachycardia and/or preexcited atrial fibrillation were recorded; one of these patients suddenly died of VF, 6 years after procedure. Conclusion. In significant proportion of WPW patients, VF was the first clinical manifestation of WPW syndrome, often precipitated by physical activity, emotional stress or inappropriate drug administration. Successful elimination of AP by percutaneous RF catheter-ablation is highly effective in secondary prevention of life-threatening tachyarrhythmias in patients with ventricular preexcitation.

Puppy socialisation programs: short and long term behavioural effects

1999 ◽  
Vol 62 (4) ◽  
pp. 335-349 ◽  
Author(s):  
Kersti Seksel ◽  
Evalynn J Mazurski ◽  
Alan Taylor
Keyword(s):  
Behavioural Effects ◽  
Short And Long Term

The influence of boar-related odours on puberty attainment in gilts

1983 ◽  
Vol 36 (1) ◽  
pp. 131-136 ◽  
Author(s):  
R. N. Kirkwood ◽  
P. E. Hughes ◽  
W. D. Booth
Keyword(s):  
Conclusive Evidence ◽  
Prolonged Treatment ◽  
Control Group ◽  
Primer Pheromone ◽  
Large White ◽  
Diethyl Ether Extract ◽  
Behavioural Effects ◽  
Unstimulated Control ◽  
Pheromone Activity

ABSTRACTThree experiments employing 40, 39 and 15 Large White × (Landrace × Large White) gilts respectively were carried out to investigate possible primer pheromone activity (i.e. regulating endocrine systems) for those 16-androstene steroids with known signalling pheromone activity (i.e. immediate behavioural effects) in the pig. Experiment 1 consisted of groups of prepubertal gilts exposed to one of the following odour sources (a) 5α-androstenone (5α-androst-16-en-3-one), (b) 3α-androstenol (5α-androst-16-en-3α-ol), (c) a mixture of both steroids, and (d) a diethyl ether extract of boar submaxillary salivary gland. Age at the onset of puberty in these gilts was compared with that in an unstimulated control group. Experiment 2 was similar to Experiment 1 except that the steroids were used at a higher concentration (100 fold), and a fifth group of gilts was exposed to an intact boar. In the third experiment, age at the onset of puberty was noted following exposure of groups of gilts to one of the following (a) a castrated boar which had received long term injections of testosterone, (b) urine from an intact boar, (c) an intact boar.The results confirmed that the intact boar accelerates puberty in gilts. Although there was no conclusive evidence indicating that isolated boar odours had an effect on the onset of puberty, it is noteworthy that of those gilts exposed to 3α-androstenol, more reached puberty earlier than control gilts. However there is the possibility that transportation may have enhanced the earlier puberty found in some of the gilts taken to a source of 3α-androstenol. Prolonged treatment of a castrated boar with testosterone did not maintain its ability to accelerate puberty in gilts.

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