PO-1783 Competitive study between estimation of lung dose using different methods for the patient size

2021 ◽  
Vol 161 ◽  
pp. S1509-S1510
Author(s):  
A. Abuhaimed ◽  
C. Martin
Keyword(s):  
Lung Dose ◽  
Patient Size

Comparison between different boost dose delivery techniques to the tumor bed of right sided breast cancer patients.

2017 ◽  
Vol 13 (1) ◽  
pp. 4605-4617
Author(s):  
Aly Mahmoud El-Hdidy
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Target Location ◽  
Breast Cancer Patients ◽  
Photon Beams ◽  
Lung Dose ◽  
Dose Volume Histograms ◽  
Tumor Bed ◽  
Boost Dose ◽  
Treatment Plans

Comparisons between three different techniques by which the boost dose was delivered to the tumor bed were carried out , aiming to present the best technique of treatment for right breast cancer patients.In this study, ten right sided breast cancer computed tomography (CT) scans were selected for ten early right breast cancer patients. We made three different treatment plans for each patient CT using three different irradiation techniques to deliver a prescribed boost dose of 10 Gy in 5 fractions to the boost PTV. In the first technique, two tangential photon beams were used, in the second technique we, two oblique photon beams were used and in the third technique, a single electron beam was used. The comparative analyses between the three techniques were performed by comparing the boost PTV- dose volume histograms (DVHs), the ipsilateral breast (right breast) DVHs, the ipsilateral lung (right lung) DVHs and the heart DVHs of the three techniques for each patient. Furthermore the dose that covering 100% , 95% of the volume (D100% , D95%) and the volume covered by 95% of the dose (V95%)of  the boost PTV of all techniques, were calculated for each patient to investigate the dose coverage of the target.Results showed that there were variations of the dose received by tumor bed, right breast and OARs depending on the technique used and the target location and size. A decrease of D100% than 90% of the prescribed dose was observed with the 3rd technique for patients 8, 9 and 10, and was observed with the 2nd technique for patient 5. A reduction of right breast dose was observed when the 3rd technique was use in comparison with the 1st and the 2nd techniques for patients 1, 2, 3, 4, 6 and 8.  Also reduction of right breast was observed when the 2nd technique used in comparison with 1st technique. An increase of lung dose was observed with the 3rd technique for patients 1, 2, 5 and 6, also was observed with 2nd technique in patient 3, 5 and 7. A decrease of lung dose was observed with the 1st technique for patients 2, 4, 5, 6, 7, 8 and 9An individualized treatment, several plans using different irradiation techniques should be developed for each patient individually to reach the best boost PTV dose coverage with minimal OARs’ dose. 

scholarly journals Use of Continuous Positive Airway Pressure (CPAP) to Limit Diaphragm Motion—A Novel Approach for Definitive Radiation Therapy for Inoperable Pleural Mesothelioma: A Pilot Study

Biology ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 711
Author(s):  
Assaf Moore ◽  
Marc J. Kindler ◽  
Aaron Max Allen
Keyword(s):  
Pilot Study ◽  
Static Field ◽  
Normal Lung ◽  
Pleural Mesothelioma ◽  
Lung Dose ◽  
Lung Inflation ◽  
Novel Approach ◽  
Recent Developments ◽  
Ct Simulation ◽  
Dose Constraints

Malignant pleural mesothelioma (MPM) is a deadly disease and radiotherapy (RT) plays an important role in its management. Recent developments in technique have made it is possible to deliver RT to MPM in the intact lung. However, it is imperative to reduce normal lung doses. We present a pilot study examining the use of CPAP and VMAT radiotherapy to reduce toxicity when treating MPM, involving three consecutive patients with MPM, not amenable to surgery, who were treated according to Helsinki committee approval. Patients were simulated using four-dimentional CT simulation with the assistance of CPAP lung inflation, then were treated using both IMRT and VMAT techniques. Radiation lung dose was optimized based on accepted lung dose constraints. Patients were followed for toxicity as well as local control and survival. Results: Three patients were treated with CPAP-based IMRT treatment. These patients tolerated the treatment and DVH constraints were able to be met. The comparison plans among the four VMAT arcs and the IMRT static field treatment were able to accomplish the treatment planning objectives without significant advantages with either technique. The treatment combined with CPAP reduced the normal lung dose in MPM patients with intact lungs. This technique is worthy of further investigation.

scholarly journals PO-0999 Functional Avoidance planning allows for lung dose reduction in radiotherapy of lung cancer

2019 ◽  
Vol 133 ◽  
pp. S550-S551
Author(s):  
K. Farr ◽  
K. West ◽  
R. Yeghiaian-Alvandi ◽  
D. Farlow ◽  
R. Stensmyr ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Dose Reduction ◽  
Lung Dose

Method of predicting the mean lung dose based on a patient׳s anatomy and dose-volume histograms

2017 ◽  
Vol 42 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Anna Zawadzka ◽  
Marta Nesteruk ◽  
Beata Brzozowska ◽  
Paweł F. Kukołowicz
Keyword(s):  
Lung Dose ◽  
Dose Volume Histograms ◽  
Dose Volume ◽  
The Mean ◽  
Mean Lung Dose

scholarly journals In x-ray computed tomography, technique factors should be selected appropriate to patient size

2001 ◽  
Vol 28 (8) ◽  
pp. 1543-1545 ◽  
Author(s):  
Walter Huda ◽  
Stewart C. Bushong ◽  
William R. Hendee
Keyword(s):  
Computed Tomography ◽  
X Ray ◽  
Patient Size ◽  
X Ray Computed

scholarly journals EP-2207: Novel volume-based algorithm rapidly optimizes lung dose in VMAT and tomotherapy for esophageal cancer

2018 ◽  
Vol 127 ◽  
pp. S1219
Author(s):  
C.X. Hsu ◽  
K.H. Lin ◽  
C.H. Chang ◽  
H.J. Tien ◽  
T.H. Wu ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Lung Dose

Design and Construction of Cervix Phantom for Brachytherapy Dose Assessment Procedure for Clinical Application

2017 ◽  
pp. 106-109
Author(s):  
Justice Avevor ◽  
Issahaku Shirazu ◽  
Samuel Nii Adu Tagoe ◽  
J. H. Amuasi ◽  
J. J. Fletcher
Keyword(s):  
Clinical Application ◽  
Excellent Result ◽  
Dose Assessment ◽  
Internal Diameter ◽  
Cylindrical Shape ◽  
Assessment Procedure ◽  
External Diameter ◽  
Actual Patient ◽  
Average Patient ◽  
Patient Size

An important point to consider in a brachytherapy dosimetry study is the design of an appropriate phantom size in calculations or experimental measurements. Perspex sheets of various size and thickness are used to design the cervix phantom. The aim of the study is to design and construct cervix phantom to mimic the pelvic segment of a standard adult human patients undergoing Brachytherapy. This is to allow assessment of dose to cervix and the surrounding tissues during cervix Brachytherapy. The methodology include; first phantom design where physical dimensions of the phantom were determined from a sampling of 30 patients’ cases to simulate an average patient size. Secondly, construction of phantom with fabricated cylindrical shape, composed of 6 mm Perspex sheets, and the assembly enclosed with the 4 mm Perspex sheet. The result of the constructed phantom had lateral separation of 34 cm, an anterior and posterior separation of 27 cm; with length of 33 cm. The Perspex pieces were glued to each other with Trichloromethane (chloroform) at room temperature. Chloroform dissolves the Perspex (PMMA), and when applied to the surfaces of the Perspex sheets, the surfaces stick together after the chloroform dries up. In forming the surface of the phantom, the 4 mm Perspex sheet was oven heated to a temperature of 140?C to make the sheet malleable. One end of the phantom was made thicker than the other end by gluing another 6 mm Perspex sheet such that the thickness of that particular end of the phantom was 12 mm. A hole of diameter 6.5 cm, which was a little bit posterior to the phantom, was created central to the 12 mm end of the phantom. The opening created was covered by 11 x 11 cm2 and 12 mm Perspex slab which was formed by gluing two 6 mm sheets together. A hole of diameter 5 cm was also made central to the cover created, such that the centre of this hole matches that of the hole on the end of the phantom. A 2.4 cm thick ring with internal diameter of 5 cm and external diameter of 6 cm was fabricated from 2.4 cm Perspex slab, which was formed from gluing four pieces of 6 mm Perspex sheets together. The fabricated ring was mounted on the 11 x 11 cm2 cover created such that the internal walls of the ring and that of the hole in the cover matches. The ring was then glued to the cover using the chloroform. The built phantom simulate actual patient anatomy and produce an excellent result to be use for clinical application.

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