Obesity and high body weights predict ledipasvir/sofosbuvir treatment failure

2017 ◽  
Vol 66 (1) ◽  
pp. S516
Author(s):  
J.B. Lai ◽  
M.A. Witt ◽  
J. Ready ◽  
M.P. Pauly ◽  
D. Witt
2018 ◽  
Vol 154 (6) ◽  
pp. S-617
Author(s):  
Soumya Kurnool ◽  
Nghia H. Nguyen ◽  
James Proudfoot ◽  
Parambir Dulai ◽  
Brigid S. Boland ◽  
...  

1980 ◽  
Vol 60 (2) ◽  
pp. 433-439 ◽  
Author(s):  
E. E. GARDINER ◽  
S. DUBETZ ◽  
G. A. KEMP

Fababeans (Vicia faba L.) were fed to broiler chicks from 1 to 28 days of age in four experiments. In experiment 1, where fababeans were the sole source of supplementary protein, body weights (ranging from 465 to 571 g) and feed-to-grain ratios differed significantly among cultivars (Maris Bead, Strubes, Pavane, Diana, Ackerperle, Fioletowy, and Kleinkoernige) but none of the fababean diets equalled the soybean meal diet. In experiment 2, supplementary protein source (soybean meal and fababean), dietary protein level (18 and 22%), methionine level (0.0 and 0.3, added), and lysine level (0.0 and 0.3, added) significantly affected body weights of chicks. Significant first-order interactions were obtained but in no case were the weights of chicks fed fababean diets equal to those fed soybean meal diets. In experiment 3, where fababeans were used to supply 25% of the 22% protein in the diets, there were no significant differences in chick weights among fababean cultivars or among the cultivars grown under different N treatments. Fababeans supported rapid weight gains (701 g) but did not equal soybean meal diets (761 g). In experiment 4, where isocaloric diets of two energy levels were used, fababeans at 20 or 40% of the diet supported as high body weights as soybean meal diets in the low energy diets. In the high energy diets, 20% fababeans also supported as high body weights as soybean meal but the 40% fababean diets did not. In none of the experiments where the diets contained fababeans was the feed-to-gain equal to that of the diets that contained only soybean meal as the protein supplement.


Genome ◽  
1988 ◽  
Vol 30 (4) ◽  
pp. 570-575 ◽  
Author(s):  
David R. C. Bailey ◽  
R. Keith Salmon ◽  
Roy T. Berg ◽  
Howard T. Fredeen

To elucidate the influence of high body weight selection on body compositional relationships, the accumulation of lipid, protein, and ash was investigated in two lines of mice selected for high 42-day body weight (H lines) and an unselected foundation population (FP). The two H lines differed in population size and were designated as the high–large (HL) and high–small (HS) lines. Logistic body growth curves revealed that HL mice exhibited an accelerated growth rate and reached a higher mature body weight than FP or HS mice. Over the range of body weights examined, HL mice had more lipid, less protein, and less ash than FP or HS mice of the same sex and body weight. However, HL lipid accumulation (relative to body weight increase) was not accelerated in comparison to that of FP mice. This study suggests that the existing model of selection-mediated compositional changes requires expansion to account for the ability of high-growth selection to direct an acceleration of body growth without a correlated enhancement of the relative rate of fat accumulation.Key words: mice, selection, body composition.


2010 ◽  
Vol 41 (11) ◽  
pp. 32
Author(s):  
ROBERT FINN
Keyword(s):  

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