P3379 Response to therapy of patients with primary pulmonary hypertension assessed by 6-minute walk test performance correlates with changes in right-ventricular mass

2003 ◽  
Vol 24 (5) ◽  
pp. 649
Author(s):  
J STRANGE
Keyword(s):  
Pulmonary Hypertension ◽  
Right Ventricular ◽  
Test Performance ◽  
Primary Pulmonary Hypertension ◽  
Response To Therapy ◽  
Walk Test ◽  
Ventricular Mass ◽  
Right Ventricular Mass ◽  
6 Minute Walk Test ◽  
Minute Walk

scholarly journals Blood Eosinophils and Pulmonary Rehabilitation in COPD

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Jafar Aljazeeri ◽  
Abdullah Sakkat ◽  
Nima Makhdami ◽  
Rayyan Almusally ◽  
Frederick Morfaw ◽  
...  
Keyword(s):  
Eosinophil Count ◽  
Pulmonary Rehabilitation ◽  
Response To Therapy ◽  
Group Differences ◽  
Walk Test ◽  
Retrospective Design ◽  
Bode Index ◽  
Blood Eosinophils ◽  
6 Minute Walk Test ◽  
Minute Walk

Background. Blood eosinophils predict the response to therapy, risk of exacerbation, and readmission in COPD. This study investigates whether blood eosinophils predict pulmonary rehabilitation (PR) outcomes in COPD. Methods. We categorized patients into eosinophilic (blood eosinophils ≥300 cells/ml) or noneosinophilic (<300 cells/ml). In a retrospective design, we compared changes within and between the two groups on BODE index, 6-minute walk test (6MWT), FEV1, and mMRC dyspnea scale. Results. Of 206 patients enrolled, 176 were included for analysis; 90 were eosinophilic. BODE index improved in both groups: (MD −1.25; 95% CI (−0.45, −4.25), P ≤ 0.001 ) in the eosinophilic and (MD −1.33; 95% CI (−1.72, −0.94), P ≤ 0.001 ) in the noneosinophilic, but a higher BODE index remained in the eosinophilic (4.98); adjusted mean change (β): 0.7 (95% CI (0.15, 1.26), P = 0.01 ). 6MWT improved by 29.3 m in the eosinophilic (95% CI (14.2, 44.4), P ≤ 0.001 ) vs. 115.1 m in the noneosinophilic (95% CI (−30.4, 260.6), P = 0.12 ). FEV1 did not change in the eosinophilic (MD −0.6; 95% CI (−2.64, 1.48), P = 0.58 ), but improved by 2.5% in the noneosinophilic (MD 2.5; 95% CI (0.77, 4.17), P = 0.005 ). There were no significant between-group differences in 6MWT and FEV1; adjusted mean changes (β) were −9.69 m (95% CI (−39.51, 20.14), P = 0.52 ) and −2.31% (95% CI (−5.69, 1.08), P = 0.18 ), respectively. There were no significant within- or between-group changes in the mMRC scale. Conclusion. Although PR improves the BODE index in both eosinophilic and noneosinophilic COPD, a higher eosinophil count (≥300 cells/ml) is associated with a higher (worse) BODE index. Blood eosinophils may predict PR outcomes.

scholarly journals Reliability, construct validity and determinants of 6-minute walk test performance in patients with chronic heart failure

2017 ◽  
Vol 240 ◽  
pp. 285-290 ◽  
Author(s):  
Nicole H.M.K. Uszko-Lencer ◽  
Rafael Mesquita ◽  
Eefje Janssen ◽  
Christ Werter ◽  
Hans-Peter Brunner-La Rocca ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Construct Validity ◽  
Test Performance ◽  
Walk Test ◽  
6 Minute Walk Test ◽  
Minute Walk

scholarly journals Value of Impedance Cardiography during 6-Minute Walk Test in Pulmonary Hypertension

2013 ◽  
Vol 6 (6) ◽  
pp. 474-480 ◽  
Author(s):  
Adriano R. Tonelli ◽  
Laith Alkukhun ◽  
Vineesha Arelli ◽  
José Ramos ◽  
Jennie Newman ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Impedance Cardiography ◽  
Walk Test ◽  
6 Minute Walk Test ◽  
Minute Walk
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