Subsequent successful pregnancy and delivery after intracytoplasmic sperm injection in a patient with XY gonadal dysgenesisms

2000 ◽  
Vol 88 (1) ◽  
pp. 101-102 ◽  
Author(s):  
Martha Dirnfeld ◽  
David Bider ◽  
Haim Abramovici ◽  
Ilan Calderon ◽  
Zeev Blumenfeld
Keyword(s):  
Intracytoplasmic Sperm Injection ◽  
Successful Pregnancy ◽  
Pregnancy And Delivery

Successful Pregnancy and Delivery in a Patient with Bladder Exstrophy

2012 ◽  
Vol 25 (3) ◽  
pp. e69-e71 ◽  
Author(s):  
Fatma Devran Bildircin ◽  
Halil Suat Ayyildiz ◽  
Migraci Tosun ◽  
Erdal Malatyalioglu ◽  
Ender Ariturk ◽  
...  
Keyword(s):  
Bladder Exstrophy ◽  
Successful Pregnancy ◽  
Pregnancy And Delivery

scholarly journals Recurrence of Chronic Myeloid Leukemia during Pregnancy Subsequently Achieving Complete Medical Remission

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Sasha Mikhael ◽  
Ashlee Pascoe ◽  
Joseph Prezzato
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Animal Studies ◽  
Kinase Inhibitors ◽  
Adverse Outcomes ◽  
High Dose ◽  
Molecular Remission ◽  
Successful Pregnancy ◽  
Pregnancy And Delivery ◽  
Reproductive Aged Women

The treatment of chronic myeloid leukemia (CML) with tyrosine kinase inhibitors (TKIs) in reproductive-aged women poses major dilemmas concerning its associated teratogenicity as observed in many animal studies. Much controversy exists regarding continuation versus discontinuation of its use in pregnancy with some studies suggesting safety of TKIs before and during pregnancy and others reporting toxicity and adverse outcomes. TKIs have become a well-established treatment option for CML, significantly improving prognosis, and yet have been reported to be fetotoxic. We present a case of a 25-year-old woman who achieved successful pregnancy and delivery after withholding treatment, meanwhile relapsing, eventually achieving complete molecular remission after reinitiation of high dose dasatinib.

scholarly journals CLINICAL CASE OF A SUCCESSFUL PREGNANCY WITH THE COMPLETE FORM OF GONADAL DYSGENESIS - SWYER SYNDROME

2019 ◽  
Vol 6 (4) ◽  
pp. 225-228
Author(s):  
Elena V. Timokhina ◽  
N. V Afanas’yeva ◽  
Yu. A Samoylova ◽  
T. M Silayeva ◽  
V. S Belousova ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Gonadal Dysgenesis ◽  
Clinical Case ◽  
Reproductive Technology ◽  
Sry Gene ◽  
Successful Pregnancy ◽  
Pregnancy And Delivery ◽  
Complete Form ◽  
Swyer Syndrome ◽  
Complete Gonadal Dysgenesis

Swyer syndrome (46,XY complete gonadal dysgenesis) is a rare chromosomal pathology. This pathology occurs with a frequency of 1 in 80,000. In genetic analysis, mutations are most often found in the following genes: the SRY gene, the NR5A1 gene, the SOX9 gene, the MAP3K1 gene. Patients with this disease develop phenotypically as women, but due to the absence of gonads and eggs, independent pregnancy is impossible. This article describes a clinical case of a successful onset, course of pregnancy and delivery in a woman with Swyer syndrome using assisted reproductive technology.

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