Investigation of the carrageenans extracted from Solieria filiformis and Agardhiella subulata from Mar Piccolo, Taranto

1997 ◽  
Vol 58 (3-4) ◽  
pp. 319-325 ◽  
Author(s):  
Erminio Murano ◽  
Renato Toffanin ◽  
Ester Cecere ◽  
Roberto Rizzo ◽  
Svein Halvor Knutsen
Dor on line ◽  
2015 ◽  
Author(s):  
Paulo Barboni
Keyword(s):  
Tnf Α ◽  
On Line ◽  
Ifn Γ ◽  

Chamada da Edição   Caros leitores, iniciando o ano de 2015 o boletim Dor On Line traz a vocês o primeiro de uma série de editoriais tendo como tema as toxinas e o estudo da dor. Ainda, e complementando nossa edição anterior, trazemos resumos apresentados em congressos no ano de 2014, mostrando aqui alertas sobre alguns trabalhos discutidos em formato de pôster no 46º Congresso Brasileiro de Farmacologia e Terapêutica Experimental, promovido pela SBFTE, Sociedade Brasileira de Farmacologia e Terapêutica Experimental, em Fortaleza - CE, de 21 a 24 de outubro de 2014. Boa Leitura!   Alertas   1. O Bloqueio do receptor de potencial transitório A1 reduz a hiperalgesia em um modelo de neuralgia do trigêmeo. 2. Avaliação da eficácia terapêutica do extrato de óleo de peixe no tratamento da dor neuropática. 3. Ativação supraespinal da via das quinureninas contribui para a manutenção da dor neuropática. 4. Ativação da aldeído-desidrogenase 2 reduz a dor neuropática e adutos de 4-hidroxinoneal. 5. O envolvimento do sistema opioidérgico na analgesia induzida por enriquecimento ambiental. 6. NOD1 E NOD2 contribuem para a gênese da dor neuropática e estão envolvidos na ativação de células gliais. 7. Polissacarídeo sulfatado derivado de algas vermelha solieria filiformis reduz hipernocicepção mecânica na articulação temporomandibular de ratos durante a artrite induzida por zymosan. 8. IFN-γ induz indoleamina (2,3)-dioxigenase (IDO) na medula espinal que contribui para a gênese da dor neuropática. 9. TNF-α participa da hipernocicepção e da inflamação induzida por cristais de urato em camundongos. 10. Investigação do papel dos receptores Toll-like 9 (TLR9) no desenvolvimento e manutenção da dor crônica inflamatória e neuropática.


Aquaculture ◽  
2021 ◽  
pp. 737091
Author(s):  
Toni J. Lohroff ◽  
Phillip R. Gillette ◽  
Hilary G. Close ◽  
Daniel D. Benetti ◽  
John D. Stieglitz

2017 ◽  
Vol 39 (4) ◽  
pp. 423 ◽  
Author(s):  
George Meredite Cunha de Castro ◽  
Norma Maria Barros Benevides ◽  
Maulori Curié Cabral ◽  
Rafael De Souza Miranda ◽  
Enéas Gomes Filho ◽  
...  

 The seaweeds are bio-resource rich in sulfated and neutral polysaccharides. The tropical seaweed species used in this study (Solieria filiformis), after dried, shows 65.8% (w/w) carbohydrate, 9.6% (w/w) protein, 1.7% (w/w) lipid, 7.0% (w/w) moisture and 15.9% (w/w) ash. The dried seaweed was easily hydrolyzed under mild conditions (0.5 M sulfuric acid, 20 min.), generating fermentable monosaccharides with a maximum hydrolysis efficiency of 63.21%. Galactose and glucose present in the hydrolyzed were simultaneously fermented by Saccharomyces cerevisiae when the yeast was acclimated to galactose and cultivated in broth containing only galactose. The kinetic parameters of the fermentation of the seaweed hydrolyzed were Y(P⁄S) = 0.48 ± 0.02 g.g−1, PP = 0.27 ± 0.04 g.L−1.h−1, h = 94.1%, representing a 41% increase in bioethanol productivity. Therefore, S. filiformis was a promising renewable resource of polysaccharides easily hydrolyzed, generating a broth rich in fermentable monosaccharides for ethanol production. 


2016 ◽  
Vol 152 ◽  
pp. 140-148 ◽  
Author(s):  
Willer M. Sousa ◽  
Renan O. Silva ◽  
Francisco F. Bezerra ◽  
Rudy D. Bingana ◽  
Francisco Clark N. Barros ◽  
...  

2010 ◽  
Vol 5 (8) ◽  
pp. 1934578X1000500 ◽  
Author(s):  
Ana Maria S. Assreuy ◽  
Grazielle C. Pontes ◽  
Natalia V. F. C. Rodrigues ◽  
Daniel M. Gomes ◽  
Paulo A. Xavier ◽  
...  

Anticoagulant and antithrombotic properties of sulfated-polysaccharides (SP) from marine algae are extensively exploited. However, reports on the vascular effects of SP from red algae are rare in the literature. The polysaccharide from Solieria filiformis (Sf-SP) was isolated by ion exchange chromatography, analyzed by agarose gel electrophoresis and tested in male Wistar rats. The inflammation studies were performed using the paw-edema model and the relaxant activity in isolated aorta precontracted with phenylephrine. The anticoagulant effect was evaluated by the test of partial thromboplastin activation time. The SP (1 mg/kg) was not antiinflammatory, but induced acute edema with maximal activity at 30 min (0.35 ± 0.04 mL) compared to controls (0.05 ± 0.03 mL). Cumulative addition of Sf-SP in phenylephrine-contracted tissues produced relaxation with maximal inhibition of 69% (IC50 29.3 ± 9.0 μg/mL) at 300 μg/mL in comparison to controls (0.51 ± 0.09 g). Sf-SP also extended human plasma coagulation time by 2.1 times. These substances could be used as important tools for the study of vascular alterations.


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