scholarly journals DANGEROUS LIAISON: SUCCESSFUL PERCUTANEOUS EDGE–TO–EDGE MITRAL VALVE REPAIR IN PATIENTS WITH END–STAGE SYSTOLIC HEART FAILURE CAN CAUSE LEFT VENTRICULAR THROMBUS FORMATION

2013 ◽  
Vol 61 (10) ◽  
pp. E1910
Author(s):  
Martin Orban ◽  
Daniel Braun ◽  
Mathias Orban ◽  
Raffael Thaler ◽  
Hasema Lesevic ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Thrombus Formation ◽  
Systolic Heart Failure ◽  
Left Ventricular ◽  
Left Ventricular Thrombus ◽  
Valve Repair ◽  
Ventricular Thrombus ◽  
End Stage

scholarly journals Left ventricular thrombus formation after successful percutaneous edge-to-edge mitral valve repair

2012 ◽  
Vol 34 (12) ◽  
pp. 942-942 ◽  
Author(s):  
Martin Orban ◽  
Hasema Lesevic ◽  
Steffen Massberg ◽  
Jörg Hausleiter
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Thrombus Formation ◽  
Left Ventricular ◽  
Left Ventricular Thrombus ◽  
Valve Repair ◽  
Ventricular Thrombus

scholarly journals Left ventricular reverse remodeling after successful subannular mitral valve repair in end-stage heart failure: a case report

2020 ◽  
Vol 4 (3) ◽  
pp. 1-5
Author(s):  
Jonas Pausch ◽  
Tatiana Sequeira Gross ◽  
Hermann Reichenspurner ◽  
Evaldas Girdauskas
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Left Ventricular ◽  
Papillary Muscles ◽  
Valve Repair ◽  
Lv Remodeling ◽  
End Stage Heart Failure ◽  
End Stage

Abstract Background Due to ongoing left ventricular (LV) remodeling and consecutive geometric displacement of both papillary muscles, end-stage heart failure is frequently associated with relevant functional mitral regurgitation (FMR) Type IIIb. Treatment strategies of FMR and their prognostic impact are still controversial. Case summary We present a case of an 80-year-old patient who suffered from recurrent symptoms of congestive heart failure due to dilated cardiomyopathy and concomitant severe FMR. To specifically address severe tethering of both mitral leaflets heart team decision was to perform minimally invasive mitral valve repair (MVR) including a subannular LV remodeling procedure, instead of an interventional edge-to-edge repair (MitraClip® procedure). In addition to mitral valve ring annuloplasty, standardized relocation of both papillary muscles was performed successfully, leading to a complete resolution of mitral leaflet tethering. There were no procedural complications and the patient was discharged with an excellent functional result without residual mitral regurgitation. Furthermore, after 12 and 24 months, he reported an increase of his functional exercise capacity and a remarkable reverse LV remodeling could be demonstrated. Discussion Novel subannular repair techniques, especially the relocation of both papillary muscles, specifically address severe leaflet tethering in FMR and have an obvious potential to improve long-term competence of MVR. Therefore, they could be considered as a viable therapeutic option even in elderly patients presenting with end-stage cardiomyopathy and severe leaflet tenting.

scholarly journals Percutaneous Mitral Valve Repair for Functional Mitral Regurgitation with End-Stage Heart Failure

2015 ◽  
Vol 21 (10) ◽  
pp. S157
Author(s):  
Yukiko Mizutani ◽  
Shunsuke Kubo ◽  
Makar Moody ◽  
Mamoo Nakamura ◽  
Takahiro Shiota ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Regurgitation ◽  
Mitral Valve Repair ◽  
Functional Mitral Regurgitation ◽  
Valve Repair ◽  
Percutaneous Mitral Valve Repair ◽  
End Stage Heart Failure ◽  
End Stage

scholarly journals Arterial thromboembolism in a young woman with occult dilated cardiomyopathy

2016 ◽  
Vol 3 (3) ◽  
pp. 12
Author(s):  
Alicia Topoll ◽  
Jordan Owens ◽  
Jorge Cheirif ◽  
J. Mark Pool ◽  
Mark Feldman
Keyword(s):  
Heart Failure ◽  
Dilated Cardiomyopathy ◽  
Systolic Heart Failure ◽  
Left Ventricular ◽  
Left Ventricular Thrombus ◽  
Caucasian Woman ◽  
Prothrombotic State ◽  
Vascular Intervention ◽  
Arterial Thromboembolism ◽  
Ventricular Thrombus

An acute dilated cardiomyopathy may present with vague symptoms including fatigue and malaise, which may delay the diagnosis until signs and symptoms of systolic heart failure develop. Left ventricular thrombus and arterial thromboembolism are rare complications of acute dilated cardiomyopathy. We present a case of a young Caucasian woman presenting with acute leg ischemia secondary to femoral artery thromboembolism associated with a previously undiagnosed acute dilated cardiomyopathy with severe systolic heart failure and a large left ventricular thrombus. Her prothrombotic state was refractory to heparin therapy and surgical vascular intervention. She eventually required leg amputation for recurrent limb ischemia with gangrene and thrombus extraction from the left ventricle. Risk factors for her prothrombotic state included the acute, dilated cardiomyopathy, use of a hormonal contraceptive agent, obesity, smoking, and a heterozygous Factor II (Prothrombin) G20110A mutation.

scholarly journals Prognostic value of hepatorenal function following transcatheter edge-to-edge mitral valve repair

2021 ◽  
Author(s):  
Tetsu Tanaka ◽  
Refik Kavsur ◽  
Maximilian Spieker ◽  
Christos Iliadis ◽  
Clemens Metze ◽  
...  
Keyword(s):  
Heart Failure ◽  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Independent Predictor ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Prognostic Impact ◽  
Composite Outcome ◽  
Valve Repair ◽  
Ventricular Ejection Fraction

Abstract Background Hepatorenal dysfunction is a strong prognostic predictor in patients with heart failure. However, the prognostic impact of the hepatorenal dysfunction in patients undergoing transcatheter mitral valve repair (TMVR) has not been well studied. Methods In consecutive patients who underwent edge-to-edge TMVR at three German centers, the model for end-stage liver disease excluding international normalized ratio (MELD-XI) score was calculated as 5.11 × ln [serum total bilirubin (mg/dl)] + 11.76 × ln [serum creatinine (mg/dl)] + 9.44. Patients were stratified into high (> 11) or low (≤ 11) MELD-XI score of which an incidence of the composite outcome, consisting of all-cause mortality and heart failure hospitalization, within 2 years after TMVR was assessed. Results Of the 881 patients, the mean MELD-XI score was 11.0 ± 5.9, and 415 patients (47.1%) had high MELD-XI score. The MELD-XI score was correlated with male, effective regurgitant orifice area, and tricuspid regurgitation severity and inversely related to left ventricular ejection fraction. Patients with high MELD-XI score had a higher incidence of the composite outcome than those with low MELD-XI score (47.7% vs. 29.8%; p < 0.0001), and in multivariable analysis, the high MELD-XI score was an independent predictor of the composite outcome [adjusted hazard ratio (HR) 1.34; 95% confidence interval (CI) 1.02–1.77; p = 0.04). Additionally, the MELD-XI score as a continuous variable was also an independent predictor (adjusted HR 1.02; 95% CI 1.00–1.05; p = 0.048). Conclusions The MELD-XI score was associated with clinical outcomes within 2 years after TMVR and can be a useful risk-stratification tool in patients undergoing TMVR.

Sign in / Sign up

Export Citation Format

Share Document