Poster #19 CHRONIC EXPOSURE TO CIGARETTE SMOKE DURING GESTATION RESULTS IN ALTERED CHOLINESTERASE ENZYME ACTIVITY AND BEHAVIORAL DEFICITS IN ADULT RAT OFFSPRING: POTENTIAL RELEVANCE TO SCHIZOPHRENIA

2012 ◽  
Vol 136 ◽  
pp. S287
Author(s):  
Alexandra I. Zugno ◽  
Daiane Fraga ◽  
Renata D. Luca ◽  
Fernando Ghedim ◽  
Pedro Deroza ◽  
...  
Author(s):  
Ginislene Dias Souza Miranda ◽  
Thalyne Aparecida Leite de Lima ◽  
Hercules de Oliveira Costermani ◽  
Camila Luiza Rodrigues dos Santos Ricken ◽  
Jocemara Patrícia Silva de Souza Parrela ◽  
...  

2016 ◽  
Vol 58 (8) ◽  
pp. 1076-1086 ◽  
Author(s):  
Maria Beatriz Barreto do Carmo ◽  
Renato Fraga Righetti ◽  
Iolanda de Fátima Lopes Calvo Tibério ◽  
Maria Helena Leite Hunziker

2019 ◽  
Vol 102 ◽  
pp. 128-138 ◽  
Author(s):  
XiaoTing Niu ◽  
XiaoYun Wu ◽  
AnNa Ying ◽  
Bei Shao ◽  
XiaoFeng Li ◽  
...  

2021 ◽  
Vol 68 (1) ◽  
pp. 222-228
Author(s):  
Ahmet Özkaya ◽  
Kenan Türkan

In this study, the effects of 3-benzoyl-7-hydroxy coumarin molecule on mineral and antioxidant enzymes were investigated in rat liver exposed to oxidative stress with aluminium chloride (AlCl3). Adult male Wistar albino rats were divided into four groups as Control, Coumarin, AlCl3, and Coumarin + AlCl3. Coumarin at the dose of 10 mg/kg and AlCl3 at the dose of 8.3 mg/kg were administered for 30 days every other day. In AlCl3 group, malondialdehyde (MDA), iron (Fe), aluminium (Al) and copper (Cu) levels increased compared to the control group, while glutathione (GSH) level, glutathione S-transferase (GST), and carboxylesterase (Ces) enzyme activity levels decreased. In Coumarin + AlCl3 group, MDA, Fe, Al and Cu levels decreased with the effect of coumarin compared to AlCl3 group, while GSH level, and GST enzyme activity levels increased. According to our results, AlCl3 generates oxidative stress in rat livers, and we believe that 3-benzoyl-7-hydroxy coumarin has an ameliorative effect on antioxidant enzyme system, Al, Fe and Cu levels.


2012 ◽  
Vol 34 (2) ◽  
pp. 153-154
Author(s):  
Didima De Groot ◽  
Jan Lammers ◽  
Ine Waalkens ◽  
Donald Fox

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