scholarly journals Regional Origin and Decrease of Pain in Patients with Depressive Symptoms Under Treatment with Venlafaxine

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
S. Begré ◽  
M. Traber ◽  
M. Gerber ◽  
R. von Känel

Aims:Worldwide data are extensively lacking in regard to patients with depressive symptoms under therapy with antidepressants in the primary care setting. We hypothesized that the magnitude of pain reduction under treatment with venlafaxine differently relates to regional origin of patients.Methods:We conducted a prospective naturalistic observational trial on 420 pain sufferers with depressive symptoms from all over Switzerland who were treated with venlafaxine by 122 physicians in primary care. Previous and additional antidepressant medication was not taken into account. Physicians rated illness severity using the Clinical Global Impression severity scale and pain intensity by means of visual analogue scales.Results:Compared with Middle European patients (ME), those from Eastern Europe (EE), and Southern Europe (SE) were younger and presented more intense overall pain mainly affecting the head, extremities and back. In addition, SE patients suffered more intense thoracic pain than ME patients, and EE patients suffered less frequently from abdominal pain compared to their ME and SE counterparts. Furthermore, 3 months after study entry, ME patients were found to profit more from treatment with venlafaxine in terms of overall illness severity and pain intensity than patients from EE and SE.

2015 ◽  
Vol 78 (6) ◽  
pp. 620
Author(s):  
G. Rioli ◽  
G. Mattei ◽  
G.M. Galeazzi ◽  
S. Ferrari ◽  
S. Bursi ◽  
...  

2021 ◽  
Vol 10 (16) ◽  
pp. 3699
Author(s):  
Simona Cammarota ◽  
Valeria Conti ◽  
Graziamaria Corbi ◽  
Luigi Di Gregorio ◽  
Pasquale Dolce ◽  
...  

This study explores which patient characteristics could affect the likelihood of starting low back pain (LBP) treatment with opioid analgesics vs. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in an Italian primary care setting. Through the computerized medical records of 65 General Practitioners, non-malignant LBP subjects who received the first pain intensity measurement and an NSAID or opioid prescription, during 2015–2016, were identified. Patients with an opioid prescription 1-year before the first pain intensity measurement were excluded. A multivariable logistic regression model was used to determine predictive factors of opioid prescribing. Results were reported as Odds Ratios (ORs) with a 95% confidence interval (CI), with p < 0.05 indicating statistical significance. A total of 505 individuals with LBP were included: of those, 72.7% received an NSAID prescription and 27.3% an opioid one (64% of subjects started with strong opioid). Compared to patients receiving an NSAID, those with opioid prescriptions were younger, reported the highest pain intensity (moderate pain OR = 2.42; 95% CI 1.48–3.96 and severe pain OR = 2.01; 95% CI 1.04–3.88) and were more likely to have asthma (OR 3.95; 95% CI 1.99–7.84). Despite clinical guidelines, a large proportion of LBP patients started with strong opioid therapy. Asthma, younger age and pain intensity were predictors of opioid prescribing when compared to NSAIDs for LBP treatment.


2007 ◽  
Vol 61 (8) ◽  
pp. 1278-1282 ◽  
Author(s):  
R. S. McIntyre ◽  
J. Z. Konarski ◽  
S. H. Kennedy ◽  
S. E. Dickens ◽  
R. M. Bagby

Author(s):  
Ralston R Lockett ◽  
Myra Michelle DeBose, PhD, MSN, MSEd, RN

Ralston Lockett, BSN, RN - FNP StudentMyra Michelle DeBose, PhD, MSN, MSEd, RN - Faculty AdvisorPrairie View A & M University - College of Nursing - Graduate Program - Houston, TXBackground: There are newly diagnosed patients in primary care settings with depressive symptomsdue to lack of communication from providers. The aim of this proposed study is to assess newlydiagnosed patients who may express depressive symptomology. Establishing a sound relationshipbetween patients and providers is essential for a trusting relationship. Patient-centeredcommunication increases better health outcomes in primary care settings. There is reason to believethat missed opportunities between patient-providers can decrease patient compliance and increasedepression.Research Hypothesis: Newly diagnosed patients that receive effective provider communication willhave a decrease in depressive symptoms as compared to newly diagnosed patients who do not receiveeffective communication.Methodology: This study uses a longitudinal, quasi-experimental research design, conveniencesampling. Up to 80 newly diagnosed patients who did not receive effective communication will beevaluated for approximately six months. The primary setting will be 2 urban area clinics in Houston,Texas. The Center for Epidemiologic Studies Depression Scale (CES-D), will be used within 30 days afterthe initial healthcare provider visit to assess depressive symptoms.Results: Depressive symptoms will be measured using the (CES-D) assessment tool of 20 – items. Thetool assesses how frequently an individual experienced depressive symptoms within a week. Inaddition, a 45 min post visit survey regarding provider communication will be sent after 30 days.Sample analysis will include diagnosis and literacy level. Participants will be asked to identify preferredmethods of communicating with their provider.Significance: There is a correlation between depressive symptoms and lack of effective communicationwith patients in a primary care setting. Poor identification of patient’s mental health status andengagement in plan of care can lead to poor patient health outcomes, increase health care costs, anddisparities to under-privilege communities.


2000 ◽  
Vol 177 (04) ◽  
pp. 289
Author(s):  
Mary Cannon

Counselling is often underestimated as a treatment for depression. Bedi et al (pp. 312–318) show that counselling is just as effective as antidepressant medication in treating depression over an 8-week period in a primary care setting. This study uses an interesting design – a partially randomised preference trial – whereby patients were either randomised or assigned to the treatment of their choice, if they had a strong preference. Surprisingly, having a preference for a particular treatment did not appear to confer any extra benefit in response. The authors point out that no particular psychotherapeutic model was employed in this study. The highly trained and experienced counsellors were allowed to adopt whatever approach they believed was most suitable for their patient.


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