Quality: A non-interventional study evaluating quality of life in schizophrenic patients treated with atypical antipsychotics in the ambulatory setting

2011 ◽  
Vol 26 (S2) ◽  
pp. 1474-1474
Author(s):  
J. Peuskens ◽  
E. Fontaine ◽  
T. Vanlerberghe
Keyword(s):  
Quality Of Life ◽  
Negative Symptoms ◽  
Atypical Antipsychotics ◽  
Short Form ◽  
Well Being ◽  
Ambulatory Setting ◽  
Subjective Well Being ◽  
Symptom Scale ◽  
Schizophrenic Patients

ObjectivesThe QUALITY study evaluated Quality-of-Life in schizophrenic patients treated with atypical antipsychotics (AAPs) in the ambulatory setting.MethodsThis study was a 9-month, observational, multicentre prospective study. Patients (18–65 years-old) diagnosed with schizophrenia and treatment started with one AAP before visit-1 (minimum: 4-weeks, maximum: 8-weeks) were enrolled into this Belgian study. At visit-1 patients’ demographics and medical history were recorded with follow-up visits after 3-, 6- and 9-months. At each visit, patients completed the Subjective Well-being under Neuroleptic treatment short form (SWN-K), while investigators assessed the Positive and Negative Symptom Scale (PANSS-8) and Global Assessment of Functioning.Results121 patients were enrolled: 91 male, mean age 36.7 ± 10.8years. The main AAPs were risperidone (38/121), apripirazole (28/121) and quetiapine (25/121). On average, most mean changes from baseline in SWN-K-subscale scores were positive (between −0.5 and +0.5, range −1.8–1.6) suggesting patients felt better, although there were no treatment-group differences. The associations between baseline SWN-K-subscales and age were small (RC [regression co-efficient] range: −0.03–0.01). PANSS-8-score changes were slightly negative (means between −0.77 and −0.43) suggesting decreased symptom severity. Patients with more severe negative symptoms considered their mental- and physical-functioning to be better throughout the study, indicated by significant correlations between these SWN-K-subscale scores and negative PANSS-scores (RC = 0.19, p = 0.0282; RC = 0.15, p = 0.0258). The associations between SWN-K-scores and positive PANSS-scores were small (RC: 0.01–0.14). The number of hospitalizations decreased during the study (9.6% between visit-1 and 2 vs. 7.5% visit-3 and −4).ConclusionsQuality-of-life for all patients seemed to improve slightly, without any differences between treatment-groups.

Quality of life of patients with Sjogren’s disease with ongoing therapy with diseasemodifying antirheumatic drugs

2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Life Quality ◽  
Well Being ◽  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Sf 36 ◽  
Disease Modifying ◽  
Sjögren’S Disease

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.

scholarly journals The Effect of the Acculturation of Chinese Immigrants on Tourist Satisfaction and Quality of Life

2021 ◽  
Vol 13 (4) ◽  
pp. 1770
Author(s):  
Taeyoung Cho ◽  
Taesoo Cho ◽  
Hao Zhang
Keyword(s):  
Quality Of Life ◽  
Cultural Change ◽  
Cultural Adaptation ◽  
Structural Equation ◽  
Chinese Immigrants ◽  
Well Being ◽  
Equation Model ◽  
Subjective Well Being ◽  
Tourist Satisfaction

Given the rapidly increasing number of foreign nationals migrating to Korea, this study investigates the relationship between cultural adaptation, tourist satisfaction, and quality of life among Chinese immigrants in Korea. A questionnaire survey was conducted among 344 Chinese immigrants in Korea who visited Gyeongju, where Korean World Heritage sites and modern tourist facilities coexist. A structural equation model was used to verify the hypothesis and indicated that cultural assimilation and cultural separation had a significant effect on tourist satisfaction, whereas cultural integration and cultural change did not have any statistically significant effect on tourist satisfaction. Additionally, tourist satisfaction had a significant effect on quality of life (in terms of subjective well-being and psychological well-being). The results of this study can function as a reference for improving Chinese immigrants’ cultural adaptation, tourist satisfaction, and quality of life.

Quality of life in long-term childhood cancer survivors and the relation of late effects and subjective well-being

2004 ◽  
Vol 13 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Sigrid Pemberger ◽  
Reinhold Jagsch ◽  
Eva Frey ◽  
Rosemarie Felder-Puig ◽  
Helmut Gadner ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Late Effects ◽  
Well Being ◽  
Childhood Cancer Survivors ◽  
Subjective Well Being

The Relevance of Personal Domain Satisfaction for the Quality of Life in South Africa

1988 ◽  
Vol 18 (3) ◽  
pp. 69-75 ◽  
Author(s):  
Valerie Møller
Keyword(s):  
Quality Of Life ◽  
South African ◽  
Well Being ◽  
Positive Influence ◽  
Subjective Well Being ◽  
South Africans ◽  
Relative Contribution ◽  
Personal Domain ◽  
The Impact

South African psychologists have identified the improvement of quality of life as a major goal of the 1980s. This paper reviews the impact of satisfaction with personal aspects of life on perceived well-being. The results of an exploratory study of South African quality of life conducted among 5 587 individuals of all population groups are discussed. Findings confirm the salience of the personal domain and the positive influence of personal satisfactions on subjective well-being. However, results of regression analyses suggest that the relative contribution of satisfactions in the personal domain is too low to play a major role in improving the quality of life of all South Africans in the longer term.

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