Validation of the european organization for research and treatment of cancer quality of life questionnaire (QLQ-C30) as a measure of psychosocial function in breast cancer patients

1998 ◽  
Vol 34 (4) ◽  
pp. 510-517 ◽  
Author(s):  
S.-A McLachlan ◽  
G.M Devins ◽  
P.J Goodwin
2021 ◽  
pp. 65-71
Author(s):  
Anastasia Putu Martha Anggarani ◽  
Raditya Kurniawan Djoar ◽  
Riza Amaliya ◽  
Fredy Eric Akbar Pamungkas

Background: Cancer is a deadly disease for anyone. One type of cancer is breast cancer. This type of cancer has a big psychological impact on sufferers because of the risk of breast removal surgery for sufferers so that cancer can destroy their future and changing quality of life. Decreased quality of life in women with breast cancer causes them to be unable to fulfill their roles, duties and also mantaining health status. Therefore, the purposes of this study are to identified quality of life women with breast cancer. Methods: The method of this study used descriptive analysis, the study was conducted in the breast cancer community in Surabaya, East Java. A total of 30 people became respondents to this study and filled in 30 questions of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C-30 (EORTC QLQ C30). Results: The general health of the patients was an 664.25, which illustrates that the quality of life for cancer patients is in moderate condition. This is because in this study the last week symptoms such as shortness of breath, weakness, pain, difficulty sleeping, loss of appetite, nausea, vomiting, difficulty defecating, diarrhea, fatigue, difficulty concentrating, tension, difficulty walking close, lying in a chair / mattress is reduced or not. They still find it difficult to do strenuous activities, walk long distances, feel worried, have difficulty remembering and exper.ience financial difficulties. However, their lives are not disrupted due to physicality or therapy Conclusion: The general health of breast cancer patients in the Surabaya breast cancer community is an 664.25, which describes the quality of life of cancer patients in moderate condition . It is expected that the hospital can socialize about the group of breast cancer to patients so that patients can share  experience, obtain various health-related information, and will make patients feel they have many friends with cancer fighters so that it will further improve the quality of life


2019 ◽  
Vol 13 (2) ◽  
pp. 55
Author(s):  
Zhafirah Ramadhanty ◽  
Kristanto Yuli Yarsa ◽  
Ari Probandari

Background: The number of breast cancer patients in Indonesia is increasing but there are still only a few researches that assess their quality of life. RAND SF-36 is a quality of life instrument that is widely used. In Indonesia, the validity and reliability of the instrument is still under development, especially in breast cancer patients. Various health status questionnaires have been used in physical rehabilitation studies involving patient with pacemaker, but for women with breast cancer, the usefulness of these questionnaires as measures of physical, mental, and social well-being has not been firmly established. Methods: A previously validated RAND SF-36 questionnaire in patients with pacemaker was given to 252 breast cancer survivor community members. We assessed the construct validity and the reliability by referring to its Pearson’s r table value and Cronbach’s α coefficient. Results: One hundred and fourteen breast cancer survivor community members participated and completed all 36 questions of the instrument between September- November 2018. Questions number 2, 28, and 35 showed lower Pearson’s r value (r<0,300) than other questions but still showed r value of >0.1548 indicating that these questions were valid. Cronbach’s α coefficient >0.90 indicated good internal consistency. Conclusions: The Indonesian version of the SF-36 quality of life questionnaire is a suitable instrument and can be used for research in Indonesian breast cancer patients.


2019 ◽  
Vol 7 (9) ◽  
pp. 1456-1460 ◽  
Author(s):  
Catherine Catherine ◽  
Vita Camellia ◽  
Muhammad Surya Husada ◽  
Bahagia Loebis ◽  
Elmeida Effendy ◽  
...  

BACKGROUND: Cancer has to become the scariest disease and tends to reduce the quality of life of the patient. Therefore, it is not only a medical treatment that needs to be conducted but also a psychological treatment. AIM: to analyse the relationship between affective psychopathology and the quality of life of breast cancer patients who are receiving radiotherapy treatment. METHODS: This research was a correlative analytical study with a cross-sectional approach using the Hospital Anxiety and Depression Scale (HADS) instrument to assess psychopathological features and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) to determine the quality of life. This research was conducted in March 2016-July 2016 at Vina Estetika Cancer Center Hospital, Medan, Indonesia. As many as 47 subjects were divided into two criteria; Inclusion criteria, participants with breast cancer who were undergoing radiotherapy, aged over 18 years, with HADS score ≥ 17, and the exclusion criteria, were patients suffering from chronic psychiatry diseases. RESULTS: Affective psychopathology was indicated to result in a significant negative correlation with the quality of life of breast cancer patients which whom were treated with radiotherapy with p = 0.035 and r = -0.267. This suggests that with a higher HADS, a decrease in quality of life will occur. CONCLUSIONS: Affective psychopathological comorbidities have a great influence on the quality of life of patients who are undergoing radiotherapy. Thus, cancer management must include screening for psychopathological morbidity. Moreover, psychological rehabilitation must also be provided along with the cancer treatment.


2021 ◽  
Vol 7 (4) ◽  
pp. 229
Author(s):  
Mizanul Adli ◽  
Hamzah Shatri ◽  
Noorwati Sutandyo ◽  
Suhendro Suwarto

Pendahuluan. Peningkatan angka ketahanan hidup pasien kanker payudara tidak selalu diikuti oleh peningkatan kualitas hidup. European Organization for Research and Treatment of Cancer (EORTC) menekankan pentingnya melakukan penilaian kualitas hidup pada pasien kanker. Saat ini, di Indonesia, belum ada kuesioner yang valid dan reliabel untuk menilai kualitas hidup pasien kanker payudara secara akurat. Penelitian ini bertujuan untuk membuktikan bahwa European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast 23 (EORTC QLQ-BR23) merupakan alat ukur yang reliabel dan valid digunakan di IndonesiaMetode. Penelitian ini adalah studi potong lintang. Penelitian dimulai dengan menerjemahkan EORTC QLQ-BR23 ke dalam bahasa Indonesia dan kemudian di uji coba pada 10 responden. Setelah itu, EORTC QLQ-BR23 hasil terjemahan digunakan pada penelitian utama dengan jumlah sampel yang lebih besar. Test-retest dinilai dengan Intraclass Correlation Coeficient (ICC). Konsistensi internal dinilai dengan cronbach alpha. Construct validity dinilai dengan multi-trait scaling analysis. Validitas kriteria dinilai dengan melihat korelasi antara domain European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Cancer30 (EORTC QLQ-C30) dan EORTC QLQ-BR23 dengan Short Form 36(SF36).Hasil. Telah dilakukan pengambilan data terhadap 100 pasien kanker payudara yang menjalani terapi dari September - Oktober 2015. Nilai ICC (interval 1 jam) pada semua domain EORTC QLQ-BR23 sangat baik (ICC > 0,8). Terdapat penurunan nilai ICC (interval 30 hari) pada semua domain EORTC QLQ-BR23. Nilai cronbach alpha > 0,7 pada hampir semua domain EORTC QLQ-BR23 kecuali domain gejala lengan (Cronbach Alpha: 0,643). Multi-trait scaling analysis menunjukkan korelasi cukup tinggi antara skor butir pertanyaan dengan skor domainnya sendiri. Sedangkan hubungan butir pertanyaan dengan domain yang berbeda selalu mempunyai korelasi yang lebih rendah dibandingkan dengan domainnya sendiri. Pada uji validitas kriteria, didapatkan 19 korelasi dengan r > 0,3 antara domain EORTC QLQ-C30 dan EORTC QLQ-BR23 dengan SF36.Simpulan. EORTC QLQ-BR23 merupakan alat ukur yang valid dan reliabel  untuk menilai kualitas hidup pasien kanker payudara di Indonesia Kata Kunci: Kualitas Hidup, EORTC QLQ-BR23, Validitas, Reliabilitas, Kanker Payudara Validity and Reability Test of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast23 in Breast Cancer Patient on TreatmentIntroduction. Improved survival of breast cancer patients are not necessarily followed by improvement of quality of life. European Organization for Research and Treatment of Cancer (EORTC) emphasize the importance of assessing the quality of life in cancer patients. Currently, in Indonesia, there has been no reliable and valid questionnaire to assess quality of life of breast cancer patients accurately. This study aims to prove that the EORTC QLQ-BR23 is valid and reliable measuring instrument used in Indonesia.Methods. This is a cross-sectional study. The study began with the EORTC QLQBR23 translated into Indonesian and then tested on 10 respondents. After that, The Indonesian version of EORTC QLQ-BR23 is used in the main study with a larger sample size. Test-retest was assessed with intraclass correlation coefficient (ICC). Internal consistency was assessed by Cronbach alpha. Construct validity was assessed by multi-trait scaling analysis. The criteria validity assessed by looking at the correlation between domains European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Cancer 30 (EORTC QLQC30) and EORTC QLQ-BR23 with Short Form 36 (SF36).Results. Data collection were done on 100 breast cancer patients on treatment from September to October 2015. ICC value (1 hour interval) in all domains of EORTC QLQ-BR23 is very good (ICC> 0.8). There is a decline in the value of ICC (30 days interval) in all domains of EORTC QLQ-BR23. Cronbach alpha values > 0.7 in almost all domains of EORTC QLQ-BR23 domain unless symptoms arm domain (Cronbach's Alpha: 0.643). Multi-trait scaling analysis showed a fairly high correlation between the scores of the questions with a score of his own domain. While the relationship of the questions with different domains always have a lower correlation than the domain itself. In criteria validity test, obtained 19 correlation with r > 0,3 between domains EORTC QLQ-C30 and EORTC QLQ-BR23 with SF36.Conclusion. EORTC QLQ-BR23 is a valid and reliable instrument for assessing quality of life of breast cancer patients in Indonesia


2021 ◽  
Author(s):  
BERNA KURT ◽  
ZEYNEP SİPAHİ KARSLI ◽  
BERNA ÖMÜR ÇAKMAK ÖKSÜZOĞLU ◽  
EMİNE ÖZTÜRK ◽  
NESLİHAN DEMİRÖRS ◽  
...  

Abstract Background The objective of this study is to evaluate the impact of peripheral neuropathy on the quality of life of breast cancer patients throughout with monthly follow-up during 4 months of paclitaxel treatment.Material and methods The research was conducted with a prospective cross sectional with four follow-ups descriptive design. The study population consisted of female patients with breast cancer at Ankara Oncology Training and Research Hospital between August 2018 and January 2019. Data were collected the ‘’Patient Information Form’’,‘’EORTC C30 Cancer Quality Of Life Questionnaire’’ and ‘’Chemotherapy-Induced Peripheral Neuropathy Assessment Tool’’. The study was undertaken in accordance with the STROBE checklist for cross-sectional studies. Results Of 79 patients included in the Chemotherapy-Induced Peripheral Neuropathy Assessment Tool except for the general activity subdimension were statistically significant in the ratings of 2nd, compared to 1st; 3rd compared to 1st and 2nd; 4th compared to 1st, 2nd, and 3rd follow-up periods. The overall mean of EORTC C30 Cancer Quality of Life Questionnaire, functional subdimension, symptom severity, and general well-being in the evaluations of 2nd, compared with 1st; 3rd compared with 1st and 2nd; 4th compared with 1st, 2nd, and 3rd follow-up periods it was found that the mean values of symptom that decreased gradually were statistically significant.Conclusion The neuropathy scale was found to be higher in 2nd, 3rd, 4th follow-up periods than in 1st follow-up. Also, EORTC C30 Cancer QLQ subdimensions were high initially but gradually decreased after the fourth cycle. Thus, it was found that the increase in neuropathy symptoms negatively affects the quality of life.


2020 ◽  
Vol 66 (1) ◽  
Author(s):  
Monique Binotto ◽  
Gilberto Schwartsmann

Introdução: O câncer de mama pode alterar a qualidade de vida relacionada à saúde das pacientes. Objetivo: Compreender o impacto da quimioterapia para câncer de mama na qualidade de vida relacionada à saúde de pacientes. Método: Trata-se de uma revisão integrativa da literatura, compreendendo artigos publicados entre 2007 e 2019, disponíveis nas bases de dados PubMed, LILACS e SciELO. Analisaram-se 25 artigos na íntegra. Resultados: Os questionários mais frequentemente utilizados nos estudos foram o European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) e o módulo complementar European Organization for Research and Treatment of Cancer Breast Cancer-specific Quality of Life Questionnaire (EORTC QLQ-BR23). Em relação às alterações da qualidade de vida, a saúde global diminui durante a quimioterapia, mas pode melhorar após o término do tratamento. O aumento dos sintomas é relatado em diversos estudos e prejudicou a qualidade de vida relacionada à saúde das pacientes. Entretanto, os sintomas diminuem após o término da quimioterapia, exceto para algumas escalas. As escalas de imagem corporal, função sexual e funcionamento físico pioram ao longo do tratamento. A qualidade de vida mental/psicológica tem oscilações durante o tratamento, assim como a escala sobre as relações sociais. Conclusão: A qualidade de vida relacionada à saúde de mulheres com câncer de mama é afetada negativamente pelo tratamento quimioterápico, expressando maior impacto nas escalas de sintomas.


2022 ◽  
Author(s):  
LIA RAQUEL DE CARVALHO VIANA ◽  
GERLANIA RODRIGUES SALVIANO FERREIRA ◽  
STHEPHANIE DE ABREU FREITAS ◽  
KATIA NEYLA DE FREITAS MACEDO COSTA

OBJETIVO: AVALIAR A QUALIDADE DE VIDA RELACIONADA À SAÚDE DE MULHERES IDOSAS EM TRATAMENTO DE CÂNCER DE MAMA. MÉTODO: ESTUDO TRANSVERSAL, DESCRITIVO, COM ABORDAGEM QUANTITATIVA, REALIZADO COM 57 MULHERES IDOSAS EM TRATAMENTO DE CÂNCER DE MAMA. A COLETA DE DADOS OCORREU DURANTE OS MESES DE JUNHO A NOVEMBRO DE 2019, POR MEIO DE UM INSTRUMENTO SEMIESTRUTURADO PARA OBTENÇÃO DE DADOS SOCIODEMOGRÁFICOS E CLÍNICOS E OS QUESTIONÁRIOS EUROPEAN ORGANIZATION FOR RESEARCH AND TREATMENT OF CANCER QUALITY OF LIFE QUESTIONNAIRE “CORE” 30 E QUALITY OF LIFE QUESTIONNAIRE – BREAST CANCER 23. OS DADOS FORAM ANALISADOS DE FORMA DESCRITIVA COM O AUXÍLIO DO STATISTICAL PACKAGE FOR THE SOCIAL SCIENCE FOR WINDOWS, VERSÃO 22.0. O PROJETO FOI APROVADO PELO COMITÊ DE ÉTICA EM PESQUISA SOB PARECER Nº 3.293.768. RESULTADOS: NA QUALIDADE DE VIDA GERAL, OBSERVOU-SE QUE AS IDOSAS APRESENTARAM BOA MÉDIA NA ESCALA DE SAÚDE GLOBAL E RAZOÁVEL NA ESCALA FUNCIONAL, DESTACANDO-SE A FUNÇÃO SOCIAL. JÁ A ESCALA DE SINTOMAS APRESENTOU MÉDIA BAIXA, DESTACANDO-SE A DIFICULDADE FINANCEIRA, INSÔNIA, FADIGA E DOR. NO QUESTIONÁRIO ESPECÍFICO, A ESCALA FUNCIONAL APRESENTOU MAIOR MÉDIA, COM DESTAQUE POSITIVO PARA A IMAGEM CORPORAL. NA ESCALA DE SINTOMAS, OS EFEITOS COLATERAIS E OS SINTOMAS DA MAMA FORAM OS QUE MAIS CONTRIBUÍRAM PARA A DETERIORAÇÃO DA QUALIDADE DE VIDA. CONCLUSÃO: A QUALIDADE DE VIDA GLOBAL APRESENTOU-SE BOA, NO ENTANTO, A MESMA SOFRE IMPACTOS DEVIDO AOS EFEITOS COLATERAIS AO TRATAMENTO.


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