Relationships between event-related potentials and neuropsychological tests in neurologically healthy adults

2003 ◽  
Vol 10 (1) ◽  
pp. 60-62 ◽  
Author(s):  
Shinichiro Maeshima ◽  
Ryuji Okita ◽  
Hiroo Yamaga ◽  
Fuminori Ozaki ◽  
Hiroshi Moriwaki
Keyword(s):  
Neuropsychological Tests ◽  
Event Related Potentials ◽  
Healthy Adults ◽  
Related Potentials

scholarly journals Dunn’s Model of Sensory Processing: An Investigation of the Axes of the Four-Quadrant Model in Healthy Adults

2019 ◽  
Vol 9 (2) ◽  
pp. 35 ◽  
Author(s):  
Alexia E. Metz ◽  
Daniella Boling ◽  
Ashley DeVore ◽  
Holly Holladay ◽  
Jo Fu Liao ◽  
...  
Keyword(s):  
Sensory Processing ◽  
Behavioral Response ◽  
Event Related Potentials ◽  
Healthy Adults ◽  
Personality Questionnaire ◽  
Passive Behavior ◽  
Related Potentials ◽  
Low Threshold ◽  
Axis I ◽  
Four Quadrant

We examined the behavioral response (BR) and threshold (T) axes of Dunn’s four-quadrant model of sensory processing (1997). We assessed whether they are ordinal ranges and if variation is associated with other similarly described characteristics: Introversion/Extraversion (I/E) of Eysenck’s personality model (Sato, 2005), and somatosensory event related potentials (SERP) and their gating (Davies & Gavin, 2007). From healthy adults (n = 139), we obtained: Adult/Adolescent Profile (A/ASP, Brown & Dunn, 2002) and Eysenck’s Personality Questionnaire, Brief Version (Sato, 2005) scores and peak amplitude and gating factor of SERP P50. We found that BR scores did not differ across normative categories of the A/ASP, but T scores significantly increased along the axis. I/E scores did not vary with BR scores. There were no differences or correlations in P50 amplitudes and gating with T scores. The findings suggest that the BR axis may not reflect a construct with ordinal range, but the T axis may. Dunn’s concept of BR appears to be distinct from Eysenck’s concept of I/E. SERP and its gating may not be directly reflective of sensory processing thresholds in healthy adults. Conclusions are limited by having few participants with passive behavior regulation or low threshold patterns of processing.

scholarly journals The effect of graded monetary reward on cognitive event-related potentials and behavior in young healthy adults

2006 ◽  
Vol 62 (2) ◽  
pp. 272-279 ◽  
Author(s):  
Rita Z. Goldstein ◽  
Lisa A. Cottone ◽  
Zhiru Jia ◽  
Thomas Maloney ◽  
Nora D. Volkow ◽  
...  
Keyword(s):  
Event Related Potentials ◽  
Healthy Adults ◽  
Monetary Reward ◽  
Related Potentials ◽  
And Behavior ◽  
Cognitive Event

Assessing Neurocognitive Dysfunction in Cranial Radiotherapy: Can Cognitive Event-related Potentials Help?

2006 ◽  
Vol 5 (2) ◽  
pp. 109-125 ◽  
Author(s):  
Robert D. Pearlstein ◽  
Crystal Whitten ◽  
Paul Haerich
Keyword(s):  
Cognitive Function ◽  
Cognitive Dysfunction ◽  
Cognitive Processing ◽  
Neuropsychological Tests ◽  
Cognitive Impairments ◽  
Event Related Potentials ◽  
Clinical Electrophysiology ◽  
Cranial Radiotherapy ◽  
Related Potentials ◽  
Cognitive Event

Cognitive changes are common sequelae of cancer and cancer treatment, particularly in patients receiving cranial radiotherapy (RT). These effects are typically assessed by subjective clinical examination or using objective neuropsychological tests. Biologically based neurophysiological methods have been increasingly applied to the study of cognitive processing in neuropsychiatric and neurological disorders and as objective measures of cognitive status for patients with dementia. These methods detect the activation of neural circuits that directly mediate cognitive function in the human brain and include metabolic and electrophysiology based techniques. Neuroimaging procedures such as 18FDG PET and more recently fMRI, which detect metabolic activation associated with cognitive processing, provide excellent spatial resolution and can be directly correlated with neuroradiological findings associated with cranial RT neurotoxicity. Clinical electrophysiology procedures such as cognitive event-related potentials (ERP), which detect the neuronal electrical activity associated with cognitive processing, offer excellent temporal resolution at low cost. Cognitive ERP techniques are already being used to assess severity and progression of cognitive dysfunction in patients with vascular and degenerative dementias, but have been largely overlooked in studies of radiation-related cognitive impairments. We review these various electrophysiological methods in the context of their relevance to assessing cranial RT effects on cognitive function, and provide recommendations for a neurophysiological approach to supplement current neuropsychological tests for RT cognitive impairments. This technology is well suited for clinical assessment of neurocognitive sequelae of cancer and should provide new insights into the mechanism of RT-related cognitive dysfunction.

Theta-Burst Stimulation Is Able to Impact Cognitive Processing: A P300 and Neuropsychological Test Study

2021 ◽  
pp. 1-11
Author(s):  
Nuno Filipe Cardoso Pinto ◽  
Marta Duarte ◽  
Helena Gonçalves ◽  
Ricardo Silva ◽  
Jorge Gama ◽  
...  
Keyword(s):  
Neuropsychological Tests ◽  
Group Performance ◽  
Event Related Potentials ◽  
Outcome Evaluation ◽  
Controlled Study ◽  
Oddball Paradigm ◽  
Theta Burst Stimulation ◽  
Burst Stimulation ◽  
Related Potentials ◽  
Theta Burst

<b><i>Introduction:</i></b> Theta-burst stimulation (TBS) is a safe non-invasive neurostimulation technique used to improve cognitive and neuropsychiatric impairments. Combined outcome evaluation using event-related potentials (ERPs) and neuropsychological tests may allow a more thorough assessment of TBS treatment efficacy; however, some mixed results have been found, and their use remains scarce. Our main objective was to evaluate whether a session of TBS to the left dorsolateral prefrontal cortex (DLPFC) can impact upon the performance of both neuropsychological and neurophysiological tests. <b><i>Methods:</i></b> This double-blind sham-controlled study involved 28 healthy adults, between 18 and 30 years. Volunteers were randomly allocated to receive excitatory (intermittent [iTBS]), inhibitory (continuous TBS [cTBS]) or sham stimulation on the left DLPFC. Subjects were evaluated using ERPs (auditory oddball paradigm P300) and neuropsychological tests (Trail making test [TMT] and Stroop test of words and colours [STWC]), using a pre-post stimulation protocol. <b><i>Results:</i></b> Inhibitory stimulation led to significantly delayed P300 peak latencies (<i>p</i> &#x3c; 0.001), with no consistent change in N2P3 amplitudes. cTBS also significantly influenced the expected group performance in Stroop C and Stroop interference (<i>p</i> = 0.025) compared to the iTBS and sham groups. No significant results were found in TMT tests after TBS. <b><i>Conclusion:</i></b> Our results suggest that P300 and specific Stroop colour and words test parameters can be similarly influenced by the same TBS protocol. This emphasizes the importance of mixed evaluation using neuropsychological and neurophysiological resources in research associated with the use of transcranial magnetic stimulation and cognition.

Psychomotor Speed Predicts Outcome in Patients with Acute Meningitis and Encephalitis: A Prospective Observational Study

2021 ◽  
pp. 155005942110311
Author(s):  
Yong Seo Koo ◽  
Soyeon An ◽  
Min-Ju Kim ◽  
Hyun-Woo Kim ◽  
Sang-Ahm Lee
Keyword(s):  
Clinical Outcomes ◽  
Neuropsychological Tests ◽  
Functional Outcomes ◽  
Severe Disease ◽  
Event Related Potentials ◽  
Oddball Paradigm ◽  
Psychomotor Speed ◽  
Neurocognitive Dysfunction ◽  
Acute Meningitis ◽  
Related Potentials

Background and Purpose. Although acute meningitis and encephalitis are known to cause cognitive dysfunction, the prognostic values of neuropsychological and neurophysiological tests in predicting clinical outcomes are seldom studied. We investigated specific neurocognitive dysfunction and event-related potentials (ERPs), which can predict functional outcomes in patients with acute meningitis and encephalitis. Methods. We enrolled consecutive adult patients with acute meningitis and encephalitis and performed neuropsychological tests and ERP studies using a passive auditory oddball paradigm at enrollment. Patient functional outcomes were assessed using the Glasgow Outcome Scale at 6 (GOS6) months after discharge. Results. Twenty-two patients were included in the study. Among 21 patients who performed neuropsychological tests, Korean-Trail Making Test-Elderly's version, Part A time (TMT-A time) correlated with GOS6, which remained significant even after controlling for age. We identified a significant association between TMT-A time and P3a latency. Post-hoc analysis showed that patients with longer TMT-A time (≥23 s) tended to have longer P3a latency than those with shorter TMT-A time. Conclusions. Decreased psychomotor speed predicted poor clinical outcomes. Because TMT-A time can be performed at the bedside in a relatively short time, this might be a useful neuropsychological biomarker to predict or monitor clinical outcomes. Furthermore, passive oddball P3a may be useful in patients with more severe disease who are unable to perform the TMT task.

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