Alcohol Consumption and Micronutrient Intake as Risk Factors for Liver Cirrhosis: A Case-Control Study

1998 ◽  
Vol 8 (3) ◽  
pp. 154-159 ◽  
Author(s):  
Giovanni Corrao ◽  
Pierfederico Torchio ◽  
Antonella Zambon ◽  
Amleto D'Amicis ◽  
Anna Raffaella Lepore ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Alcohol Consumption ◽  
Case Control Study ◽  
Case Control ◽  
Micronutrient Intake ◽  
Control Study

scholarly journals Tobacco smoking and alcohol consumption as risk factors for thymoma – A European case-control study

2019 ◽  
Vol 61 ◽  
pp. 133-138 ◽  
Author(s):  
Mikael Eriksson ◽  
Linda Kaerlev ◽  
Preben Johansen ◽  
Noemia Afonso ◽  
Wolfgang Ahrens ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alcohol Consumption ◽  
Tobacco Smoking ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Investigating the Synergistic Interaction of Diabetes, Tobacco Smoking, Alcohol Consumption, and Hypercholesterolemia on the Risk of Pancreatic Cancer: A Case-Control Study in Italy

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Giuseppe La Torre ◽  
Antonella Sferrazza ◽  
Maria Rosaria Gualano ◽  
Chiara de Waure ◽  
Gennaro Clemente ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pancreatic Cancer ◽  
Alcohol Consumption ◽  
Case Control Study ◽  
Smoking Status ◽  
Conditional Logistic Regression ◽  
Case Control ◽  
Synergistic Interaction ◽  
Independent Risk Factors ◽  
Control Study

The aims of the present research are to investigate the possible predictors of pancreatic cancer, in particular smoking status, alcohol consumption, hypercholesterolemia, and diabetes mellitus, in patients with histologically confirmed pancreatic carcinoma and to examine the synergism between risk factors. A case-control study (80 patients and 392 controls) was conducted at the Teaching Hospital “Agostino Gemelli” in Rome. A conditional logistic regression was used for the statistical analysis and results were presented as odds ratio (OR) and 95% confidence intervals (95% CI). We also investigated the possible interactions between risk factors and calculated the synergism index (SI). The multivariate analysis revealed that hypercholesterolemia and alcohol consumption resulted in important risk factors for pancreatic cancer even after the adjustment for all variables (OR: 5.05, 95% CI: 2.94–8.66; OR: 2.25, 95% CI: 1.30–3.89, resp.). Interestingly, important synergistic interactions between risk factors were found, especially between ever smoking status and alcohol consumptions (SI = 17.61) as well as alcohol consumption and diabetes (SI = 17.77). In conclusion, the study confirms that hypercholesterolemia and alcohol consumption represent significant and independent risk factors for pancreatic cancer. Moreover, there is evidence of synergistic interaction between diabetes and lifestyle factors (drinking alcohol and eating fatty foods).

scholarly journals Tobacco smoking and alcohol consumption as risk factors for glioma: a case-control study in Melbourne, Australia.

1996 ◽  
Vol 50 (4) ◽  
pp. 442-446 ◽  
Author(s):  
S F Hurley ◽  
J J McNeil ◽  
G A Donnan ◽  
A Forbes ◽  
M Salzberg ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alcohol Consumption ◽  
Tobacco Smoking ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Shared Medical and Environmental Risk Factors in Dry Eye Syndrome, Sjogren’s Syndrome, and B-Cell Non-Hodgkin Lymphoma: A Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Hadas Ben-Eli ◽  
Doron J. Aframian ◽  
Eldad Ben-Chetrit ◽  
Dror Mevorach ◽  
Geffen Kleinstern ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
B Cell ◽  
Dry Eye ◽  
Case Control Study ◽  
Case Control ◽  
Non Hodgkin Lymphoma ◽  
History Of ◽  
Control Study

Objectives. To assess whether there are shared exposures associated with Sjogren’s syndrome (SS), dry eye syndrome (DES), and B-cell non-Hodgkin lymphoma (B-NHL), in order to determine whether they are etiologically related. Methods. In a clinic-based case-control study, 702 participants (91 SS, 120 DES, 211 (age and sex frequency-matched) controls, and 280 B-NHL cases) were recruited and interviewed regarding exposures, medical history, and family history. Results. Female predominance was noted in SS (ratio 9.2 : 1). Eye dryness was severest in SS compared to DES and controls (P<0.001). Compared to controls, alcohol consumption was inversely associated with NHL, DES, and SS (odds ratio OR=0.47, 95% confidence interval (CI): 0.31-0.71; OR=0.54, 95% CI: 0.33-0.88; and OR=0.26, 95% CI: 0.14-0.49, respectively), while a previous history of infection requiring hospitalization was positively associated with all three conditions: NHL (OR=1.92; 95% CI: 1.23-2.99), DES (OR=3.29; 95% CI: 1.97-5.47), and SS (OR=4.74; 95% CI: 2.66-8.44). NHL patients were more likely to report first-degree relatives with hematologic cancer, while having first-degree relatives with an autoimmune disease (AID) was associated with SS (OR=5.25; 95% CI: 2.59-10.63) and DES (OR=3.55; 95% CI: 1.83-6.91) compared to controls. Conclusions. Some exposures are associated with all three conditions (such as an inverse association with alcohol consumption and a positive association with serious past infection), while a family history of AID appears to be shared by DES and SS, but not NHL subjects. Shared risk factors for all three conditions indicate possible mutual etiological pathways.

Association between liver cirrhosis and peri-implant diseases: a case-control study on implant- and patient-related risk factors

2021 ◽  
Author(s):  
Fernando Oliveira Costa ◽  
Sheila Cavalca Cortelli ◽  
José Roberto Cortelli ◽  
Eugênio José Pereira Lages ◽  
Gustavo Henrique Mattos Pereira ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Case Control Study ◽  
Case Control ◽  
Related Risk ◽  
Control Study

Risk factors for low-grade neuroendocrine carcinoma (LGNET): Hospital-based case-control study in US

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 4641-4641
Author(s):  
M. Hassan ◽  
C. Dagohoy ◽  
C. Leary ◽  
D. Li ◽  
J. C. Yao
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Alcohol Consumption ◽  
Cigarette Smoking ◽  
Case Control Study ◽  
Case Control ◽  
Cancer Center ◽  
Low Grade ◽  
History Of ◽  
Control Study

4641 Background: There has been an increase in the diagnosed incidence of LGNET in US over the last 2 decades. Little is known about the etiology of LGNET. In this hospital-based, case-control study we evaluated the association of cigarette smoking, alcohol consumption, diabetes mellitus (DM) and family history of cancers with LGNET of different sites. Method: Cases were patients with LGNET referred to The University of Texas M.D. Anderson Cancer Center between 12/1999 and 9/2005. Controls were selected from healthy individuals who accompanied patients with other cancers. Logistic regression was applied to estimate the adjusted odds ratio (AOR) and 95% confidence interval (CI) for potential risk factors and demographic characteristics. Result: We identified 951 LGNET patients with primary sites including appendix (n=102, 10.7%), small bowel (n=234, 24.6%), lung (n=149, 15.7%), pancreas (n=166, 17.5%), stomach (n=55, 5.8%), rectum (n=56, 5.9%), and others (n=189, 19.2%). Cases were compared to 924 controls. Majority of subjects were white-race (cases, 79.7%; controls, 89.5%). Gender distribution was similar in LGNET patients with 1:1 ratio. DM was associated with pancreatic and gastric primary sites; AOR and 95% CI were 2.5 (1.6–3.9) and 4.5 (2.2–9.3) respectively. Ever cigarette smoking was associated with lung carcinoid (OR=1.3; 95%CI, 1.01–1.9) especially among heavy smokers (20 cigarettes per day), (OR=1.7; 95%CI, 1.01–2.9). Ever or heavy alcohol consumption (= 60 ml ethanol/day) was not significantly related to LGNET of any site. The significantly elevated risk for carcinoid tumors extended to participants with a family history of breast, colon, esophageal, pancreas, prostate, and renal cancers after adjustment for demographic and environmental risk factors (P<.05). Conclusion: Smoking, DM, and family history may increase the risk of LGNET of various sites. Determining environmental and genetic factors related to LGNET may lead to development of surveillance and prevention strategies for high-risk individuals. No significant financial relationships to disclose.

Risk factors for symptomatic gallstones in patients with liver cirrhosis: a case-control study

2003 ◽  
Vol 98 (8) ◽  
pp. 1856-1860 ◽  
Author(s):  
Monica Acalovschi ◽  
Dan Blendea ◽  
Cristina Feier ◽  
Alfred I. Letia ◽  
Nadia Ratiu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Cirrhosis ◽  
Case Control Study ◽  
Case Control ◽  
Symptomatic Gallstones ◽  
Control Study
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