Increased disorderliness and decreased mass and daily rate of endogenous growth hormone secretion in adult turner syndrome: the impact of body composition, maximal oxygen uptake and treatment with sex hormones

1998 ◽  
Vol 8 (4) ◽  
pp. 289-298 ◽  
Author(s):  
Claus Højbjerg Gravholt ◽  
Johannes D. Veldhuis ◽  
Jens Sandahl Christiansen
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Oxygen Uptake ◽  
Turner Syndrome ◽  
Endogenous Growth ◽  
Maximal Oxygen Uptake ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Daily Rate ◽  
The Impact

scholarly journals Body Image Disturbance in Acromegaly Patients Compared to Nonfunctioning Pituitary Adenoma Patients and Controls

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Helen M. Conaglen ◽  
Dennis de Jong ◽  
Veronica Crawford ◽  
Marianne S. Elston ◽  
John V. Conaglen
Keyword(s):  
Growth Hormone ◽  
Body Image ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Primary Diagnosis ◽  
Body Image Disturbance ◽  
Separate Analysis ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Impact

Purpose. Excess growth hormone secretion in adults results in acromegaly, a condition in which multiple physical changes occur including bony and soft tissue overgrowth. Over time these changes can markedly alter a person’s appearance. The aim of this study was to compare body image disturbance in patients with acromegaly to those with nonfunctioning pituitary adenomas (NFAs) and controls and assess the impact of obesity in these groups.Methods. A cross-sectional survey including quality of life, body image disturbance, anxiety and depression measures, growth hormone, and BMI measurement was carried out.Results. The groups did not differ with respect to body image disturbance. However separate analysis of obese participants demonstrated relationships between mood scales, body image disturbance, and pain issues, particularly for acromegaly patients.Conclusions. While the primary hypothesis that acromegaly might be associated with body image disturbance was not borne out, we have shown that obesity together with acromegaly and NFA can be associated with body image issues, suggesting that BMI rather than primary diagnosis might better indicate whether patients might experience body image disturbance problems.

scholarly journals Effects of Growth Hormone Secretion on Body Composition in Patients with Crohn’s Disease

2003 ◽  
Vol 88 (11) ◽  
pp. 5468-5472 ◽  
Author(s):  
Laurence Katznelson ◽  
Wesley P. Fairfield ◽  
Nebras Zeizafoun ◽  
Bruce E. Sands ◽  
Mark A. Peppercorn ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Hormone Secretion ◽  
Growth Hormone Secretion

Effect of exogenous growth hormone administration on endogenous growth hormone secretion induced by a met-enkephalin analog

1996 ◽  
Vol 134 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Giuseppe Fanciulli ◽  
Osvaldo Oliva ◽  
Paolo A Tomasi ◽  
Alessandra Pala ◽  
Alba Bertoncelli ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Endogenous Growth ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Inhibitory Effect ◽  
Growth Hormone Administration ◽  
Gh Secretion ◽  
Hormone Administration ◽  
Exogenous Growth ◽  
Serum Gh

Fanciulli G, Oliva O, Tomasi PA. Pala A. Bertoncelli A, Dettori A, Delitala G. Effect of exogenous growth hormone administration on endogenous growth hormone secretion induced by a met-enkephalin analog. Eur J Endocrinol 1996:134:73–6. ISSN 0804–4643 Exogenous growth hormone (hGH) administration in humans attenuates the endogenous growth hormone (GH) response to some pharmacological stimuli: in particular, pretreatment with hGH completely blocks the serum GH response to growth hormone-releasing hormone. In order to evaluate the mechanism(s) whereby opioids induce GH secretion in man, we gave the following treatments to six healthy male volunteers: (a) IV saline: (b) a met-enkephalin analog G-DAMME 250 μg IV as a bolus at time ′: (c) hGH 2 IU as an IV bolus at time −180′; (d) G-DAMME as above, preceded by hGH as above. In our study. G-DAMME stimulated GH secretion both basally (peak 17.9 ± 6.0 ng/ml) and, to a lesser extent, after hGH pretreatment (6.0 ± 2.7 ng/ml). Since in our study G-DAMME was able to partially overcome the inhibitory effect of hGH administration, it is suggested that opioids act through an inhibition of somatostatin release and not through a GHRH-dependent pathway. However, an additional direct effect of hGH on pituitary somatotrophes cannot be excluded. Giuseppe Delitala, Chair of Endocrinology, Viale S. Pietro 12, University of Sassari, 07100 Sassari. Italy

Reduced Growth Hormone Secretion in Turner Syndrome: Is Body Weight a Key Factor?

1994 ◽  
Vol 41 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Stefano Cianfarani ◽  
Fabrizio Vaccaro ◽  
Anna Maria Pasquind ◽  
Sabatino A. Marchione ◽  
Franca Passeri ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Turner Syndrome ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Key Factor

Body composition and spontaneous growth hormone secretion in normal short stature children.

1994 ◽  
Vol 78 (2) ◽  
pp. 277-282
Author(s):  
J E Abdenur ◽  
C V Solans ◽  
M M Smith ◽  
C Carman ◽  
M T Pugliese ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Short Stature ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Spontaneous Growth
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