Effects of condensed tannins and crude sesquiterpene lactones extracted from chicory on the motility of larvae of deer lungworm and gastrointestinal nematodes

2003 ◽  
Vol 52 (3) ◽  
pp. 209-218 ◽  
Author(s):  
Abdul L. Molan ◽  
Adrian J. Duncan ◽  
Tom N. Barry ◽  
Warren C. McNabb
2019 ◽  
pp. 01-09
Author(s):  
Suarez VH ◽  
Olmos LH ◽  
Martinez GM ◽  
Sandoval GV ◽  
Alfaro EJ ◽  
...  

In order to evaluate condensed tannins (CT) effect on dairy goat gastrointestinal nematodes (GIN) under a grazing and confined systems, two experiments (E1 and E2) were made. On both, goats were kept in two groups of 10 animals each. Groups were: control, without treatment (CG) and CT supplemented (CTG) daily with 25 g (1,25%) in E1 and 75 g (2%) in E2. During the E1, feeding was based on Lucerne (Medicago sativa) grazing and supplementation with 500 g of corn grain and during the E2, stabled milking goats ate 500 g of corn grain and ad libitum lucerne hay. Biweekly, faecal egg counts (FEC) and coprocultures were made. In addition, FAMACHA© technique, body condition score (BCSS) and ingested food were recorded each two weeks during the 90 days (E1) and 76 (E2) days of trial. The FEC values in most of the study were low and no significant differences (p<0.78) were detected between groups. Mean FEC were 534 (CTG) and 357 (CG) during E1 and 509 (CTG) and 484 (CG) during E2. The predominant NGI genera were Trichostrongylussp. (48.1%), Haemonchus sp. (39.9%) and Teladorsagia sp. (12.0%). FAMACHA© scores did not show significant (p<0.41) differences between groups, but the CG (median=3) showed a BCS significantly (p<0.05) higher than those of CTG (median=2.5). The average milk production did not present statistically significant differences between groups (p<0.57), between sampling dates (p<0.23) and group x sampling dates (p<0.65). Under the conditions of these studies 25g or 75 g of CT in the diet had no anthelmintic or productive effects. Keywords: Gastrointestinal nematode; Dairy goat; Condensed tannin; Production


2019 ◽  
Vol 72 (6) ◽  
pp. 946-953 ◽  
Author(s):  
Rafael Arturo Torres-Fajardo ◽  
Jorge Augusto Navarro-Alberto ◽  
Javier Ventura-Cordero ◽  
Pedro Geraldo González-Pech ◽  
Carlos Alfredo Sandoval-Castro ◽  
...  

2014 ◽  
Vol 205 (3-4) ◽  
pp. 725-729 ◽  
Author(s):  
Livio M. Costa-Júnior ◽  
Jailson S. Costa ◽  
Ítala C.P.D. Lôbo ◽  
Alexandra M.S. Soares ◽  
Adibe L. Abdala ◽  
...  

Parasitology ◽  
2016 ◽  
Vol 143 (4) ◽  
pp. 444-454 ◽  
Author(s):  
OLIVIER DESRUES ◽  
CHRISTOS FRYGANAS ◽  
HONORATA M. ROPIAK ◽  
IRENE MUELLER-HARVEY ◽  
HEIDI L. ENEMARK ◽  
...  

SUMMARYPlants containing condensed tannins (CT) may have potential to control gastrointestinal nematodes (GIN) of cattle. The aim was to investigate the anthelmintic activities of four flavan-3-ols, two galloyl derivatives and 14 purified CT fractions, and to define which structural features of CT determine the anti-parasitic effects against the main cattle nematodes. We used in vitro tests targeting L1 larvae (feeding inhibition assay) and adults (motility assay) of Ostertagia ostertagi and Cooperia oncophora. In the larval feeding inhibition assay, O. ostertagi L1 were significantly more susceptible to all CT fractions than C. oncophora L1. The mean degree of polymerization of CT (i.e. average size) was the most important structural parameter: large CT reduced larval feeding more than small CT. The flavan-3-ols of prodelphinidin (PD)-type tannins had a stronger negative influence on parasite activity than the stereochemistry, i.e. cis- vs trans-configurations, or the presence of a gallate group. In contrast, for C. oncophora high reductions in the motility of larvae and adult worms were strongly related with a higher percentage of PDs within the CT fractions while there was no effect of size. Overall, the size and the percentage of PDs within CT seemed to be the most important parameters that influence anti-parasitic activity.


2003 ◽  
Vol 9 ◽  
pp. 101-111
Author(s):  
S.O. Hoskin ◽  
T.N. Barry ◽  
P.R. Wilson

The productivity and health of farmed deer is improved by substituting perennial ryegrass-based pasture with forages containing condensed tannins (CT) and/or sesquiterpene lactones. Benefits have included improved lactation, growth, trace element status, resilience to internal parasites and reductions in parasite larval development. Forages evaluated for deer include the forage legumes sulla and birdsfoot tref oil, which contain CT, and the herb chicory, which contains both CT and sesquiterpene lactones. Autumn grazing of weaner deer on chicory has shown growth can be increased whilst anthelmintic requirement reduced compared to grazing of perennial ryegrass/ white clover pasture. The importance of secondary compounds relative to other nutritive characteristics of alternative forage species, such as low fibre and highly digestible carbohydrate concentrations, have not been fully characterised, but they are likely to contribute to improved deer health. Unlike sheep and cattle, deer pr oduce salivary proteins that bind CT, allowing them to consume plants containing higher CT concentrations than sheep and cattle. The effect of CT upon the digestion and absorption of protein, which has been determined for other domestic ruminants, needs to be measured in deer fed forage diets, to establish if beneficial effects exist. In vitro work has shown direct inhibitory effects of CT and sesquiterpene lactones extracted from forages on deer internal parasite larvae. The faeces, rumen and abomasal fluid of deer grazing chicory also contained substances reducing the viability of parasite larvae. Alternative plant species such as chicory, birdsfoot trefoil and forage willows containing secondary compounds will play an important role in low chemical sustainable deer farming. Keywords: anthelmintic, Cichorium intybus,condensed tannins, forage, Hedysarum coronarium, internal parasites, protein, red deer


Parasitology ◽  
2016 ◽  
Vol 143 (10) ◽  
pp. 1279-1293 ◽  
Author(s):  
MIGUEL PEÑA-ESPINOZA ◽  
STIG M. THAMSBORG ◽  
OLIVIER DESRUES ◽  
TINA V. A. HANSEN ◽  
HEIDI L. ENEMARK

SUMMARYTwo experiments studied the effects of dietary chicory against gastrointestinal nematodes in cattle. In Experiment (Exp.) 1, stabled calves were fed chicory silage (CHI1;n= 9) or ryegrass/clover hay (CTL1;n= 6) with balanced protein/energy intakes between groups. After 16 days, all calves received 10 000Ostertagia ostertagiand 66 000Cooperia oncophorathird-stage larvae (L3) [day (D) 0 post-infection (p.i.)]. In Exp. 2, calves were assigned to pure chicory (CHI2;n=10) or ryegrass/clover (CTL2;n= 10) pastures. After 7 days, animals received 20 000O. ostertagiL3/calf (D0 p.i.) and were moved regularly preventing pasture-borne infections. Due to poor regrowth of the chicory pasture, CHI2was supplemented with chicory silage. At D40 p.i. (Exp. 1) and D35 p.i. (Exp. 2) calves were slaughtered for worm recovery. In Exp.1, fecal egg counts (FEC) were similar between groups. However,O. ostertagicounts were significantly reduced in CHI1by 60% (geometric mean;P< 0·01), whereasC. oncophoraburdens were unaffected (P= 0·12). In Exp. 2, FEC were markedly lowered in CHI2from D22 p.i onwards (P< 0·01).Ostertagia ostertagiadult burdens were significantly reduced in CHI2by 66% (P< 0·001). Sesquiterpene lactones were identified only in chicory (fresh/silage). Chicory shows promise as an anti-Ostertagiafeed for cattle and further studies should investigate its on-farm use.


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