Development of gliomas: potential role of asymmetrical cell division of neural stem cells

2004 ◽  
Vol 5 (8) ◽  
pp. 511-514 ◽  
Author(s):  
François Berger ◽  
Emmanuel Gay ◽  
Laurent Pelletier ◽  
Philippe Tropel ◽  
Didier Wion
Keyword(s):  
Stem Cells ◽  
Cell Division ◽  
Neural Stem Cells ◽  
Potential Role ◽  
Asymmetrical Cell Division

scholarly journals Characteristics of Neural Stem Cells Expanded in Lowered Oxygen and the Potential Role of Hypoxia-Inducible Factor-1Alpha

Neurosignals ◽  
2006 ◽  
Vol 15 (5) ◽  
pp. 259-265 ◽  
Author(s):  
Cui-ping Zhang ◽  
Ling-ling Zhu ◽  
Tong Zhao ◽  
Huiqing Zhao ◽  
Xin Huang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Potential Role ◽  
Hypoxia Inducible Factor

Potential role of NF‐κB in adult neural stem cells: the underrated steersman?

2006 ◽  
Vol 24 (2-3) ◽  
pp. 91-102 ◽  
Author(s):  
Darius Widera ◽  
Ilja Mikenberg ◽  
Barbara Kaltschmidt ◽  
Christian Kaltschmidt
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Potential Role ◽  
Adult Neural Stem Cells

Tissue regeneration and repair in multiple sclerosis: the role of neural stem cells

2011 ◽  
pp. 60-66
Author(s):  
Stefano Pluchino ◽  
Roberto Furlan ◽  
Luca Muzio ◽  
Gianvito Martino
Keyword(s):  
Multiple Sclerosis ◽  
Stem Cells ◽  
Neural Stem Cells ◽  
Tissue Regeneration

The role of morphine on rat neural stem cells viability, neuro-angiogenesis and neuro-steroidgenesis properties

2017 ◽  
Vol 636 ◽  
pp. 205-212 ◽  
Author(s):  
Nima Abdyazdani ◽  
Alireza Nourazarian ◽  
Hojjatollah Nozad Charoudeh ◽  
Masoumeh Kazemi ◽  
Navid Feizy ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells

P50. Role of glioma produced CM1 in the brain tumor tropism of human neural stem cells

2010 ◽  
Vol 80 ◽  
pp. S33-S34
Author(s):  
J. Jeon ◽  
S. Cho ◽  
K. Cho ◽  
Y. Lee ◽  
M. Lee
Keyword(s):  
Stem Cells ◽  
Brain Tumor ◽  
Neural Stem Cells ◽  
Human Neural Stem Cells ◽  
Tumor Tropism ◽  
The Brain

scholarly journals Phase Separation and Mechanical Forces in Regulating Asymmetric Cell Division of Neural Stem Cells

2021 ◽  
Vol 22 (19) ◽  
pp. 10267
Author(s):  
Yiqing Zhang ◽  
Heyang Wei ◽  
Wenyu Wen
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Phase Separation ◽  
Cell Division ◽  
Neural Stem Cells ◽  
Asymmetric Cell Division ◽  
Stem Cell Population ◽  
Mechanical Forces ◽  
Major Mechanism ◽  
Asymmetrically Distributed

Asymmetric cell division (ACD) of neural stem cells and progenitors not only renews the stem cell population but also ensures the normal development of the nervous system, producing various types of neurons with different shapes and functions in the brain. One major mechanism to achieve ACD is the asymmetric localization and uneven segregation of intracellular proteins and organelles into sibling cells. Recent studies have demonstrated that liquid-liquid phase separation (LLPS) provides a potential mechanism for the formation of membrane-less biomolecular condensates that are asymmetrically distributed on limited membrane regions. Moreover, mechanical forces have emerged as pivotal regulators of asymmetric neural stem cell division by generating sibling cell size asymmetry. In this review, we will summarize recent discoveries of ACD mechanisms driven by LLPS and mechanical forces.

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