Abstract #909: The Effect of Continuous Use of Oral Contraceptives on Serum Levels of Antimüllerian Hormone and Implications for Preserving Ovarian Reserve from Damage from Chemotherapy

2015 ◽  
Vol 21 ◽  
pp. 182
Author(s):  
Jerome Check ◽  
Gabrielle DiAntonio
Keyword(s):  
Oral Contraceptives ◽  
Ovarian Reserve ◽  
Serum Levels ◽  
Antimullerian Hormone ◽  
Antimüllerian Hormone ◽  
Continuous Use

scholarly journals The Effect of Cyclophosphamide Chemotherapy on Ovarian AntiMüllerian Hormone Levels in Breast Cancer Patients

2018 ◽  
pp. 61
Author(s):  
Elisabeth G.K. Liga ◽  
Nusratuddin Abdullah ◽  
Eddy Tiro ◽  
St. Maisuri T. Chalid
Keyword(s):  
Breast Cancer ◽  
Prospective Study ◽  
Cancer Patients ◽  
Ovarian Reserve ◽  
Obstet Gynecol ◽  
Serum Levels ◽  
Breast Cancer Patients ◽  
Hormone Levels ◽  
Antimullerian Hormone ◽  
Antimüllerian Hormone

Objective: To evaluate cyclophosphamide effects on Anti-Müllerian hormone (AMH) levels in breast cancer patientstreated with cyclophosphamide chemotherapy.Methods: This cohort prospective study was conducted inDr. Wahidin Sudirohusodo Hospital in the Department of Obstetricsand Gynecology in collaboration with Department of Surgery,Faculty of Medicice, Universitas Hasanuddin between September2015 and June 2016. Serum levels of AMH from forty breast cancerpatients received three series of cyclophosphamide chemotherapydetermined by Enzyme Linked Immuno Sorbent Assay (ELISA).Results: Serum AMH levels decreased significant in the first series(from 2.092.04 g/ml to o.651.06 g/ml; p<0.05) through thethird series (from 1.531.34 g/ml to 0.50.65 g/ml; p<0.05) ofcyclophosphamide chemotherapy.Conclusion: AMH levels decreased significant after cyclophosphamideindicated that cyclosphosphamide decrease ovarianreserve.[Indones J Obstet Gynecol 2018; 6-1: 64-67]Keywords: anti-müllerian hormone, breast cancer, cyclophosphamide,ovarian reserveObjective: To evaluate cyclophosphamide effects on Anti-Müllerian hormone (AMH) levels in breast cancer patientstreated with cyclophosphamide chemotherapy.Methods: This cohort prospective study was conducted inDr. Wahidin Sudirohusodo Hospital in the Department of Obstetricsand Gynecology in collaboration with Department of Surgery,Faculty of Medicice, Universitas Hasanuddin between September2015 and June 2016. Serum levels of AMH from forty breast cancerpatients received three series of cyclophosphamide chemotherapydetermined by Enzyme Linked Immuno Sorbent Assay (ELISA).Results: Serum AMH levels decreased significant in the first series(from 2.092.04 g/ml to o.651.06 g/ml; p<0.05) through thethird series (from 1.531.34 g/ml to 0.50.65 g/ml; p<0.05) ofcyclophosphamide chemotherapy.Conclusion: AMH levels decreased significant after cyclophosphamideindicated that cyclosphosphamide decrease ovarianreserve.Keywords: anti-müllerian hormone, breast cancer, cyclophosphamide,ovarian reserve

Effect of laparoscopic excision of endometriomas on ovarian reserve: serial changes in the serum antimüllerian hormone levels

2012 ◽  
Vol 97 (6) ◽  
pp. 1472-1478 ◽  
Author(s):  
Hale Goksever Celik ◽  
Erbil Dogan ◽  
Emre Okyay ◽  
Cagnur Ulukus ◽  
Bahadir Saatli ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Hormone Levels ◽  
Antimullerian Hormone ◽  
Laparoscopic Excision ◽  
Antimüllerian Hormone

Positive cross talk between FOXL2 and antimüllerian hormone regulates ovarian reserve

2014 ◽  
Vol 102 (3) ◽  
pp. 847-855.e1 ◽  
Author(s):  
Mira Park ◽  
Dae-Shik Suh ◽  
Kangseok Lee ◽  
Jeehyeon Bae
Keyword(s):  
Cross Talk ◽  
Ovarian Reserve ◽  
Antimullerian Hormone ◽  
Antimüllerian Hormone

scholarly journals CH50 Activity and its Relationship to Antimüllerian Hormone in Patients with Infertility

2021 ◽  
Vol 1 (3) ◽  
Author(s):  
José Manuel Lozano Sánchez
Keyword(s):  
Ovarian Reserve ◽  
Spearman Correlation ◽  
Complement Pathway ◽  
Cross Sectional ◽  
Vitro Fertilization ◽  
Tertiary Referral Center ◽  
Antimullerian Hormone ◽  
Age Related ◽  
Antimüllerian Hormone

Objective: To study the importance of immunological screening (CH50, C3, C4) to determine the correlation between the ovarian reserve and complement pathway. Design: A cross-sectional multivariate study. Setting: Single tertiary referral center. Patients: 40 Women with infertility diagnosis who underwent In Vitro Fertilization (IVF). Intervention(s): Basal blood samples collected to measure complement pathway and antimüllerian hormone. Main Outcome Measure(s): To correlate complement pathways (CH50 levels) with AMH. Results: The complement system and ovarian reserve were studied in 40 women aged from 28-48 years (mean=37.87 years), finding the values of CH50 65-268 CAE (mean=153.2 CAE), C3 13.9- 183mg/dl (mean=128.52mg/dl), C4 11.5-106mg/dl (mean=29.86mg/dl), AMH 0.10-3.9ng/dl (mean=1.32ng/dl). A multivariate analysis comparison was also conducted yielding significant results: negative correlation between AMH and age (Spearman correlation -0.6; P=0.001), as well as between AMH and CH50 (Spearman correlation -0.4; P=0.0129). Conclusion: High CH50 levels are correlated with an AMH decrease and it could be accordingly associated with age-related chronic inflammation. Capsule: High levels of CH50 are correlated with a decrease in AMH levels and could also be considered as a marker of poor response in IVF cycles.

Antimüllerian hormone serum levels: a putative marker for ovarian aging

2002 ◽  
Vol 77 (2) ◽  
pp. 357-362 ◽  
Author(s):  
Annemarie de Vet ◽  
Joop S.E. Laven ◽  
Frank H. de Jong ◽  
Axel P.N. Themmen ◽  
Bart C.J.M. Fauser
Keyword(s):  
Serum Levels ◽  
Ovarian Aging ◽  
Antimullerian Hormone ◽  
Antimüllerian Hormone ◽  
Putative Marker

scholarly journals Potential Mechanisms for Racial and Ethnic Differences in Antimüllerian Hormone and Ovarian Reserve

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Reshef Tal ◽  
David B. Seifer
Keyword(s):  
Ethnic Groups ◽  
Racial Differences ◽  
Ethnic Differences ◽  
Ovarian Reserve ◽  
Pubertal Timing ◽  
Reproductive Potential ◽  
Racial And Ethnic Differences ◽  
Antimullerian Hormone ◽  
Antimüllerian Hormone ◽  
Racial Ethnic

Accumulating evidence suggests that reproductive potential and function may be different across racial and ethnic groups. Racial differences have been demonstrated in pubertal timing, infertility, outcomes after assisted reproductive technology (ART) treatment, and reproductive aging. Recently, racial differences have also been described in serum antimüllerian hormone (AMH), a sensitive biomarker of ovarian reserve, supporting the notion that ovarian reserve differs between racial/ethnic groups. The existence of such racial/ethnic differences in ovarian reserve, as reflected by AMH, may have important clinical implications for reproductive endocrinologists. However, the mechanisms which may underlie such racial differences in ovarian reserve are unclear. Various genetic factors and environmental factors such as obesity, smoking, and vitamin D deficiency which have been shown to correlate with serum AMH levels and also display significant racial/ethnic variations are discussed in this review. Improving our understanding of racial differences in ovarian reserve and their underlying causes may be essential for infertility treatment in minority women and lead to better reproductive planning, improved treatment outcomes, and timely interventions which may prolong reproductive lifespan in these women.

Role of ovarian reserve markers, antimüllerian hormone and antral follicle count, as aneuploidy markers in ongoing pregnancies and miscarriages

2015 ◽  
Vol 103 (5) ◽  
pp. 1221-1227.e2 ◽  
Author(s):  
Maribel Grande ◽  
Virginia Borobio ◽  
Mar Bennasar ◽  
Iosifina Stergiotou ◽  
Immaculada Mercadé ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Antral Follicle ◽  
Antral Follicle Count ◽  
Antimullerian Hormone ◽  
Antimüllerian Hormone ◽  
Ovarian Reserve Markers
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