608 DOWN-REGULATION OF TACHYKININ RECEPTOR GENE EXPRESSION IN PATIENTS WITH INTERSTITIAL CYSTITIS IS MEDIATED BY MICRORNAS

2009 ◽  
Vol 8 (4) ◽  
pp. 272
Author(s):  
V. Sanchez-Freire ◽  
F.C. Burkhard ◽  
U.E. Studer ◽  
T.M. Kessler ◽  
A. Kuhn ◽  
...  
Keyword(s):  
Gene Expression ◽  
Interstitial Cystitis ◽  
Receptor Gene ◽  
Down Regulation ◽  
Tachykinin Receptor ◽  
Receptor Gene Expression

MICRORNAS MEDIATE DOWN-REGULATION OF TACHYKININ RECEPTOR GENE EXPRESSION IN INTERSTITIAL CYSTITIS/ PAINFUL BLADDER SYNDROME

2009 ◽  
Vol 181 (4S) ◽  
pp. 17-17
Author(s):  
Veronica Sanchez-Freire ◽  
Fiona C Burkhard ◽  
Urs E Studer ◽  
Thomas M. Kessler ◽  
Annette Kuhn ◽  
...  
Keyword(s):  
Gene Expression ◽  
Interstitial Cystitis ◽  
Receptor Gene ◽  
Painful Bladder Syndrome ◽  
Down Regulation ◽  
Tachykinin Receptor ◽  
Painful Bladder ◽  
Receptor Gene Expression

Increased tachykinin receptor gene expression in asthmatic lung and its modulation by steroids

1993 ◽  
Vol 11 (1) ◽  
pp. 1-7 ◽  
Author(s):  
I M Adcock ◽  
M Peters ◽  
C Gelder ◽  
H Shirasaki ◽  
C R Brown ◽  
...  
Keyword(s):  
Gene Expression ◽  
Chronic Inflammation ◽  
Northern Blot Analysis ◽  
Receptor Gene ◽  
Sensory Nerves ◽  
R Gene ◽  
Dexamethasone Treatment ◽  
Tachykinin Receptor ◽  
Neurokinin 1 ◽  
Receptor Gene Expression

ABSTRACT Substance P has several inflammatory effects on the airways mediated via neurokinin 1 receptors (NK1Rs) and, if released from sensory nerves, may amplify the chronic inflammation seen in asthma. Northern blot analysis of NK1R mRNA in lung showed a 52 ± 10% (s.e.m.; P<0·01) increase in mRNA in the asthmatic lung compared with non-asthmatic control tissue. NK1R mRNA was reduced by 84·5 ± 1·9% after incubation with dexamethasone (1 μm) for 3 h (P<0·01). In contrast, NK2R mRNA was unaltered in asthmatic lungs and dexamethasone treatment had no effect on the level of NK2R mRNA. These results suggest that chronic inflammation in asthma may result in increased NK1R gene expression and that this effect is reversed by glucocorticosteroids.

Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells

2015 ◽  
Vol 40 (3) ◽  
pp. 895-900 ◽  
Author(s):  
Francesca Felicia Caputi ◽  
Donatella Carretta ◽  
Francesca Lattanzio ◽  
Martina Palmisano ◽  
Sanzio Candeletti ◽  
...  
Keyword(s):  
Gene Expression ◽  
Opioid Receptor ◽  
Receptor Gene ◽  
Down Regulation ◽  
Human Neuroblastoma ◽  
Proteasome Subunit ◽  
Receptor Gene Expression

scholarly journals Down-Regulation by cAMP of Angiotensin II Type 2 Receptor Gene Expression in PC12 Cells.

1996 ◽  
Vol 19 (4) ◽  
pp. 271-279 ◽  
Author(s):  
Satoshi Murasawa ◽  
Hiroaki Matsubara ◽  
Kazuhisa Kijima ◽  
Katsuya Maruyama ◽  
Naohiko Ohkubo ◽  
...  
Keyword(s):  
Gene Expression ◽  
Angiotensin Ii ◽  
Pc12 Cells ◽  
Receptor Gene ◽  
Down Regulation ◽  
Receptor Gene Expression
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