P273 A cross-sectional observational study of clinical and demographical factors affecting work disability and health related quality of life in Crohn's disease patients

Abstract Background: Identifying and understanding the variables that influence health-related quality of life (HRQoL) in patients with thalassemia is critical to creating more appropriate clinical, counseling, and social support programs to develop treatment results for these individuals. The purpose of this investigation is to investigate the variables that are related with HRQOL in thalassemic patients in Yemen. Methods: From July to September 2020, a descriptive, cross-sectional investigation was carried out among Thalassemia patients who attended the Yemen Society for Thalassemia. a total of 344 individuals with Thalassemia between the ages of 5 and 18 years old. Data were gathered by utilizing the Pediatric Quality of Life 4.0 as face to face interview with children and their parents. The scale consisted of four domains (Physical, emotional, social, and school functioning) and other related demographic and clinical characteristics of the patients. coefficient tests as appropriate. Two-tailed, p-value <0.05 was regarded statistically considerable.Results:The findings of the investigation displayed that the Thalassemia patients were males with a percentage of (54.9%)Thetotal HRQoL mean score was found to be (50.6±16.5) with the highest mean scores in the social (69.3±20.2) and emotional (55.9±20.7) functioning domains. There was correlation between age, education, residency, and total HRQoL scores, which was statistically significant (P-value<0.05). There was correlation between iron overload complications, pre-transfusion Hb level, received iron chelation, and total HRQoL scores (P-value<0.05).Conclusions:Appropriate programs focused at providing psychological support to thalassemia patients are needed to improve their HRQoL. The results also supported the significance of keeping a pretransfusion hemoglobin level of at least 9-10.5 g/dL prior to the transfusion procedure.

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Protocol for a cross-sectional study on factors affecting health-related quality of life among Afghan refugees in Pakistan

F1000Research ◽

10.12688/f1000research.73005.1 ◽

2021 ◽

Vol 10 ◽

pp. 971

Author(s):

Atta Ur Rehman ◽

Rubeena Zakar ◽

Muhammad Zakria Zakar ◽

Ume Hani ◽

Florian Fischer

Keyword(s):

Quality Of Life ◽

Health Care ◽

Cross Sectional Study ◽

Health Related Quality ◽

Cross Sectional ◽

Factors Affecting ◽

Afghan Refugees ◽

Related Quality ◽

Health Related

Background: Pakistan served as a host for more than 1.4 million Afghan refugees for more than 40 years. Access to health care is the most important issue faced by refugees, because they might be at a higher risk for certain diseases. This risk can be attributed to a lack of awareness of health care facilities, health beliefs, inadequate hygiene, cultural differences, and malnutrition. Health of individuals is closely associated with their quality of life. Quality of life over the whole lifespan is pivotal to overall life satisfaction. It includes physical wellbeing, mental health, education, occupation, income, personal safety, as well as (religious) freedom. Until now, the health status of Afghan refugees has never been comprehensively investigated in Pakistan. Therefore, an assessment in this regard is needed to explore their health-related quality of life, for securing their human right to health. Methods: A cross-sectional study has been designed to describe and explain the health-related quality of life of Afghan refugees in Pakistan. Multistage cluster sampling was applied for selection of study participants. The number of respondents from two regions in Pakistan was drawn through a proportionate sampling technique. A quantitative research method using pre-validated questionnaires was used for data collection. The questionnaire included items to assess well-being, mental health, health literacy, and factors affecting health and health care. Descriptive analysis was used, whereas inferential statistical tests (binary logistic regression model) was also performed. The study received ethically permission by the Advanced Studies and Research Board of the University of the Punjab, Lahore, Pakistan. Discussion: The assessment of Afghan refugee’s quality of life in Pakistan should lead to recommendations disseminated to public and health care officials. This evidence is needed for policymaking related to adequate measures for improving health conditions of Afghan refugees in Pakistan.

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Health-related quality of life of patients diagnosed with COPD in Extremadura, Spain: results from an observational study

Health and Quality of Life Outcomes ◽

10.1186/s12955-019-1244-4 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 1

Author(s):

María Merino ◽

◽

Renata Villoro ◽

Álvaro Hidalgo-Vega ◽

Concepción Carmona

Keyword(s):

Quality Of Life ◽

Observational Study ◽

Education Level ◽

Stepwise Multiple Regression ◽

Health Related Quality ◽

Cross Sectional ◽

Related Quality ◽

Health Related ◽

St George's Respiratory Questionnaire

Abstract Background COPD is a high prevalence chronic disease that involves large reductions of health-related quality of life (HRQL) of patients. This study aims to describe the HRQL of patients with COPD in Extremadura (Spain). Methods This is a cross-sectional observational study carried out using a representative sample of patients diagnosed with COPD in Extremadura. The inclusion criteria were patients of legal age, diagnosed with COPD at least 12 months prior to the visit, residing in Extremadura, with electronic medical records available for the 12 months prior to the visit and providing informed consent. The intervention aimed to elicit HRQL indicators obtained from two validated questionnaires: EuroQol - 5 Dimensions - 5 Levels (EQ-5D-5L), and St. George’s Respiratory Questionnaire-COPD (SGRQ-C). The main outcome measures were general HRQL (utility and visual analogue scale) and specific quality of life of COPD patients (total score and three component scores: Symptoms, Activity, and Impacts). Stepwise multiple regression analysis was applied to evaluate the association of EQ-5D-5L and SGRQ-C with respect to clinical and sociodemographic characteristics of the patients. Results We recruited 386 patients (mean age 71.8 ± 10.3 years, 76.2% males). In the EQ-5D-5L, participants reported greater problems with respect to mobility (56.5%) and pain/discomfort (48.2%). The mean utility was 0.72 ± 0.31, and the SGRQ-C total score was 40.9 ± 25.0. The results of both questionnaires were associated with number of exacerbations in the last 12 months, level of COPD severity, gender, and education level of the patient (p < 0.05). Conclusions The results for both utility and total SGRQ-C score indicate that having suffered exacerbations in the last year, presenting a higher level of severity, being a woman, and having a low education level are related to worse HRQL in patients with COPD.

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