scholarly journals Mental health and HIV: research priorities related to the implementation and scale up of ‘treat all’ in sub-Saharan Africa

2018 ◽  
Vol 4 ◽  
pp. 16-25 ◽  
Author(s):  
Angela M. Parcesepe ◽  
Charlotte Bernard ◽  
Robert Agler ◽  
Jeremy Ross ◽  
Marcel Yotebieng ◽  
...  
Keyword(s):  
Mental Health ◽  
Scale Up ◽  
Research Priorities ◽  
Sub Saharan Africa ◽  
Hiv Research ◽  
Sub Saharan ◽  
Treat All

The Sub-Saharan Africa Regional Partnership (SHARP) for Mental Health Capacity-Building Scale-Up Trial: Study Design and Protocol

2020 ◽  
pp. appi.ps.2020000
Author(s):  
Bradley N. Gaynes ◽  
Christopher F. Akiba ◽  
Mina C. Hosseinipour ◽  
Kazione Kulisewa ◽  
Alemayehu Amberbir ◽  
...  
Keyword(s):  
Mental Health ◽  
Capacity Building ◽  
Study Design ◽  
Scale Up ◽  
Sub Saharan Africa ◽  
Regional Partnership ◽  
Sub Saharan

scholarly journals The African Guide: One Year Impact and Outcomes from the Implementation of a School Mental Health Literacy Curriculum Resource in Tanzania

2017 ◽  
Vol 5 (4) ◽  
pp. 64 ◽  
Author(s):  
Stanley Kutcher ◽  
Yifeng Wei ◽  
Heather Gilberds ◽  
Adena Brown ◽  
Omary Ubuguyu ◽  
...  
Keyword(s):  
Mental Health ◽  
Health Literacy ◽  
Mental Health Literacy ◽  
Positive Impact ◽  
Scale Up ◽  
Sub Saharan Africa ◽  
Health Concern ◽  
Care Providers ◽  
Sub Saharan ◽  
One Year

little research is available. Schools are an ideal location in which to address mental health literacy. A Canadian school-based mental health literacy resource was adapted for application in sub-Saharan Africa called the African Guide (AG). The AG is a classroom ready curriculum resource addressing all aspects of mental health literacy. Herein we provide teacher reported activity impacts and MHL outcomes from the implementation of the AG in Tanzania. Following training, survey data addressing teacher reported AG impact and MHL outcomes was collected at three time points over a one year period. Over a period of one year, 32 teachers from 29 different schools reported that over: 4,600 students were taught MHL; 150 peer teachers were trained on the AG; 390 students approached teachers with a mental health concern; 450 students were referred to previously trained community care providers for diagnosis and treatment of Depression; and most students were considered to have demonstrated improved or very much improved knowledge, attitudes and help-seeking efficacy, with similar outcomes reported for teachers. Results of this study demonstrate a substantial positive impact on MHL related activities and outcomes for both students and teachers using the AG resource in Tanzania. Taken together with previously published research on enhancing MHL in both Malawi and Tanzania, if replicated in another setting, these results will provide additional support for the scale up of this intervention across sub-Saharan Africa.

scholarly journals The Sub-Saharan Africa Regional Partnership (SHARP) for Mental Health Capacity Building: a program protocol for building implementation science and mental health research and policymaking capacity in Malawi and Tanzania

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Christopher Fittipaldi Akiba ◽  
Vivian Go ◽  
Victor Mwapasa ◽  
Mina Hosseinipour ◽  
Bradley Neil Gaynes ◽  
...  
Keyword(s):  
Mental Health ◽  
Capacity Building ◽  
Scale Up ◽  
Sub Saharan Africa ◽  
Evidence Based ◽  
Regional Partnership ◽  
Sub Saharan ◽  
Building Program ◽  
Capacity Building Program ◽  
Research And Policy

Abstract Background Mental health (MH) disorders in low and middle-income countries (LMICs) account for a large proportion of disease burden. While efficacious treatments exist, only 10% of those in need are able to access care. This treatment gap is fueled by structural determinants including inadequate resource allocation and prioritization, both rooted in a lack of research and policy capacity. The goal of the Sub-Saharan Africa Regional Partnership for Mental Health Capacity Building (SHARP), based in Malawi and Tanzania, is to address those research and policy-based determinants. Methods SHARP aims to (1) build implementation science skills and expertise among Malawian and Tanzanian researchers in the area of mental health; (2) ensure that Malawian and Tanzanian policymakers and providers have the knowledge and skills to effectively apply research findings on evidence-based mental health programs to routine practice; and (3) strengthen dialogue between researchers, policymakers, and providers leading to efficient and sustainable scale-up of mental health services in Malawi and Tanzania. SHARP comprises five capacity building components: introductory and advanced short courses, a multifaceted dialogue, on-the-job training, pilot grants, and “mentor the mentors” courses. Discussion Program evaluation includes measuring dose delivered and received, participant knowledge and satisfaction, as well as academic output (e.g., conference posters or presentations, manuscript submissions, grant applications). The SHARP Capacity Building Program aims to make a meaningful contribution in pursuit of a model of capacity building that could be replicated in other LMICs. If impactful, the SHARP Capacity Building Program could increase the knowledge, skills, and mentorship capabilities of researchers, policymakers, and providers regarding effective scale up of evidence-based MH treatment.

scholarly journals Renal Function is Preserved Following Tenofovir Disoproxil Fumarate (TDF) Initiation Among Rwandan’s Living with HIV

2020 ◽  
Author(s):  
Gallican Nshogoza Rwibasira ◽  
Hae-Young Kim ◽  
Christella Twizere ◽  
Donald R Hoover ◽  
Qiuhu Shi ◽  
...  
Keyword(s):  
Renal Function ◽  
Tenofovir Disoproxil Fumarate ◽  
Scale Up ◽  
Sub Saharan Africa ◽  
People Living With Hiv ◽  
First Line ◽  
Antiretroviral Drug ◽  
Sub Saharan ◽  
Treat All ◽  
Living With Hiv

Abstract Background: Tenofovir disoproxil fumarate (TDF) is the antiretroviral drug most commonly associated with renal dysfunction. However, few studies have examined this association in sub-Saharan Africa despite recent scale-up of antiretroviral therapy (ART) to all people living with HIV (Treat All) in this region. We assessed estimated glomerular filtration rate (eGFR) change among HIV infected Rwandan adults following first line TDF-based therapy initiation.Methods: This prospective, observational study was conducted in 10 Rwandan health centers. Participants were ART-naive adults (≥18 years) living with HIV who initiated TDF-based ART from 1st July 2016 through 30th July 2018. The primary outcome was eGFR change from pre- (within 12 months) to post-TDF initiation (within 6 months).Results: Of 476 patients with pre- and post- TDF eGFR measurements, 264 (55.5%) were women and mean age was 35.9 years (SD 9.6). Mean pre-TDF eGFR was 92.4 (SD 24.0) and mean post-TDF was 96.0 (SD 21.0) mL/min/1.73m2. Mean pre- to post-TDF change thus increased 3.60 (SD, 26.6) mL/min/1.73m2 (p=0.001). Conclusion: We detected a statistically significant clinically small renal function improvement within 6 months following TDF initiation among 476 ART-naïve patients. This supports continued TDF use for first-line treatment.

scholarly journals Renal function is preserved following Tenofovir Disoproxil Fumarate (TDF) initiation among Rwandan’s living with HIV

2020 ◽  
Author(s):  
Gallican N. Rwibasira ◽  
Hae-Young Kim ◽  
Christella Twizere ◽  
Donald R Hoover ◽  
Qiuhu Shi ◽  
...  
Keyword(s):  
Renal Function ◽  
Tenofovir Disoproxil Fumarate ◽  
Scale Up ◽  
Sub Saharan Africa ◽  
People Living With Hiv ◽  
First Line ◽  
Antiretroviral Drug ◽  
Sub Saharan ◽  
Treat All ◽  
Living With Hiv

ABSTRACTBackgroundTenofovir disoproxil fumarate (TDF) is the antiretroviral drug most commonly associated with renal dysfunction. However, few studies have examined this association in sub-Saharan Africa despite recent scale-up of antiretroviral therapy (ART) to all people living with HIV (Treat All) in this region. We assessed estimated glomerular filtration rate (eGFR) change among HIV infected Rwandan adults following first line TDF-based therapy initiation.MethodsThis prospective, observational study was conducted in 10 Rwandan health centers. Participants were ART-naive adults (≥18 years) living with HIV who initiated TDF-based ART from 1st July 2016 through 30th July 2018. The primary outcome was eGFR change from pre-(within 12 months) to post-TDF initiation (within 6 months).ResultsOf 476 patients with pre- and post-TDF eGFR measurements, 264 (55.5%) were women and mean age was 35.9 years (SD 9.6). Mean pre-TDF eGFR was 92.4 (SD 24.0) and mean post-TDF was 96.0 (SD 21.0) mL/min/1.73m2. Mean pre-to post-TDF change thus increased 3.60 (SD, 26.6) mL/min/1.73m2 (p=0.001).ConclusionWe detected a statistically significant clinically small renal function improvement within 6 months following TDF initiation among 476 ART-naïve patients. This supports continued TDF use for first-line treatment.

scholarly journals Positioning for success: building capacity in academic competencies for early-career researchers in sub-Saharan Africa

2019 ◽  
Vol 6 ◽  
Author(s):  
C. Merritt ◽  
H. Jack ◽  
W. Mangezi ◽  
D. Chibanda ◽  
M. Abas
Keyword(s):  
Mental Health ◽  
Capacity Building ◽  
Low Cost ◽  
Early Career ◽  
Sub Saharan Africa ◽  
Training Experience ◽  
African Countries ◽  
Early Career Researchers ◽  
Academic Competencies ◽  
Sub Saharan

Background. Capacity building is essential in low- and middle-income countries (LMICs) to address the gap in skills to conduct and implement research. Capacity building must not only include scientific and technical knowledge, but also broader competencies, such as writing, disseminating research and achieving work–life balance. These skills are thought to promote long-term career success for researchers in high-income countries (HICs) but the availability of such training is limited in LMICs. Methods. This paper presents the contextualisation and implementation of the Academic Competencies Series (ACES). ACES is an early-career researcher development programme adapted from a UK university. Through consultation between HIC and LMIC partners, an innovative series of 10 workshops was designed covering themes of self-development, engagement and writing skills. ACES formed part of the African Mental Health Research Initiative (AMARI), a multi-national LMIC-led consortium to recruit, train, support and network early-career mental health researchers from four sub-Saharan African countries. Results. Of the 10 ACES modules, three were HIC-LMIC co-led, four led by HIC facilitators with LMIC training experience and three led by external consultants from HICs. Six workshops were delivered face to face and four by webinar. Course attendance was over 90% and the delivery cost was approximately US$4500 per researcher trained. Challenges of adaptation, attendance and technical issues are described for the first round of workshops. Conclusions. This paper indicates that a skills development series for early-career researchers can be contextualised and implemented in LMIC settings, and is feasible for co-delivery with local partners at relatively low cost.

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