scholarly journals The impact of multiparametric MRI on utilization of nerve sparing and surgical margins status in patients with clinically localized prostate cancer treated with robot-assisted radical prostatectomy

2020 ◽  
Vol 19 ◽  
pp. e1773
Author(s):  
G. Giannarini ◽  
R. Girometti ◽  
S. Pizzolitto ◽  
F. Zattoni ◽  
C. Valotto ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Multiparametric Mri ◽  
Surgical Margins ◽  
Localized Prostate Cancer ◽  
Nerve Sparing ◽  
Robot Assisted ◽  
The Impact

Quality of Preoperative Biopsy Is a Risk Factor for Positive Surgical Margins in Organ-Confined Prostate Cancer Treated with Nerve-Sparing Robot-Assisted Radical Prostatectomy

2015 ◽  
Vol 95 (4) ◽  
pp. 465-471 ◽  
Author(s):  
Zentia B�tow ◽  
Stefan Schunk ◽  
Martin Janssen ◽  
Stefan Gr�ber ◽  
Matthias Saar ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Risk Factor ◽  
Radical Prostatectomy ◽  
Surgical Margins ◽  
Nerve Sparing ◽  
Robot Assisted ◽  
Positive Surgical Margins ◽  
Preoperative Biopsy

scholarly journals Multiparametric MRI in planning of organ-sparing robot-assisted radical prostatectomy for treatment of localized prostate cancer with low and intermediate risk of progression

2021 ◽  
Vol 22 (2) ◽  
pp. 35-44
Author(s):  
I. A. Rezvikh ◽  
L. M. Rapoport ◽  
L. L. Chuvalov ◽  
E. S. Belisheva ◽  
A. A. Chibarov ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Localized Prostate Cancer ◽  
Nerve Sparing ◽  
Intermediate Risk ◽  
Anterior Surface ◽  
Robot Assisted ◽  
Study Objective ◽  
Tumor Lesion

The study objective is to study the role of multiparametric magnetic resonance imaging (mpMRI), to predict extracapsular extension, infiltration of the seminal vesicles, neurovascular bundles and status of positive surgical margin (PSM) in robot-assisted radical prostatectomy (RARP) with fascio- and nerve-sparing and anatomy-sparing techniques in patients with low and intermediate oncological risk; to evaluate safety of RARP with anatomy-sparing techniques in the context of oncological results in the studied patient cohort.Materials and methods. Fifty-four males underwent mpMRI in the device with magnetic field density 3 Tesla without endorectal coil. Results of mpMRI were analyzed using PI-RADS v.2. Prostate-specific antigen level, results of prostate biopsy, nomogram were analyzed. All patients were included into groups with low and intermediate oncological risk. The patients underwent RARP with anatomy-sparing techniques. Gross specimen removed during the surgery was stained with tissue stain DECOLA and subjected to stepwise pathomorphological analysis. Comparative analysis of tumor lesion localization was performed for mpMRI and pathomorphological examination. The study concentrated on the largest tumor lesion locations. The anterior surface of the prostate was examined in detail. Patients were classified per risk groups in accordance with the National Comprehensive Cancer Network (NCCN) and D'Amico criteria.Results. Full or partial overlap of the lesions per mpMRI and pathomorphological examination were observed in 48 (88.9 %) patients; locations of tumor lesions disagreed in 6 (11.1 %) patients. PSM was detected in 8 (14.8 %) patients; among them in 7 (12.9 %) the size was between 0.1 and 0.4 cm. On the anterior surface of the prostate 3 (5.5 %) PSM were observed, 2 of which were between 0.14 and 0.4 cm, 1 was multifocal, larger than 0.3 cm. Per mpMRI results and histological examination, the anterior surface (fibromuscular stroma) was affected in 14 (25.9 %) and 11 (20.4 %) cases, respectively. Among them, lesion locations overlapped in 11 observations. Results of anatomy-sparing RARP show increased PSM rate compared to traditional nerve-sparing based on the anterior surface of the prostate.Conclusion. Routine mpMRI for patients who are planned to undergo RARP allows to justify selection of anatomy-sparing RARP or rejection of modification in favor of more thorough dissection. mpMRI plays a significant role on planning of anatomy-sparing RARP, achievement of negative surgical margin in patients with low and intermediate risk of oncological progression. Evaluation of the location and size of cancer lesion in the prostate allows to plan for special aspects of anatomy- and/or nerve-sparing techniques, achieve lower PSM rate, optimize oncological and functional surgical results in localized prostate cancer.

Risk factors associated with positive surgical margins following radical prostatectomy for clinically localized prostate cancer: Can nerve-sparing surgery increase the risk?

2012 ◽  
Vol 48 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Martin Andreas Røder ◽  
Frederik Birkebæk Thomsen ◽  
Ib Jarle Christensen ◽  
Birgitte Grønkær Toft ◽  
Klaus Brasso ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Risk Factors ◽  
Radical Prostatectomy ◽  
Surgical Margins ◽  
Localized Prostate Cancer ◽  
Nerve Sparing ◽  
Positive Surgical Margins ◽  
Factors Associated

scholarly journals Multiparametric MRI before robot-assisted radical prostatectomy allows for a greater utilization of nerve sparing with no detrimental impact on surgical margins status

2020 ◽  
Vol 20 ◽  
pp. S45
Author(s):  
G. Giannarini ◽  
R. Girometti ◽  
F. Bonato ◽  
S. Pizzolitto ◽  
F. Zattoni ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Multiparametric Mri ◽  
Surgical Margins ◽  
Nerve Sparing ◽  
Robot Assisted ◽  
Detrimental Impact

scholarly journals Robotic Management of Localized Adenocarcinoma Prostate with Large Vesical Calculus: A Report of Two Cases

2016 ◽  
Vol 50 (1) ◽  
pp. 36-38 ◽  
Author(s):  
Girdhar Singh Bora ◽  
Prem Nath Dogra ◽  
Prabhjot Singh
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Bladder Outlet Obstruction ◽  
Outlet Obstruction ◽  
Perioperative Period ◽  
Localized Prostate Cancer ◽  
Special Group ◽  
Robot Assisted ◽  
Vesical Calculus ◽  
Bladder Calculi

ABSTRACT Introduction Bladder outlet obstruction (BOO) accounts for more than 75% of cases of vesical calculi in patients aged above 50 years. There are special group of patients who have large vesical calculus with localized adenocarcinoma prostate requiring treatment for both bladder calculi and malignancy. We are sharing our technique of extraperitoneal robot-assisted radical prostatectomy (RRP) and removal of vesical calculus in two patients of localized adenocarcinoma prostate with large vesical calculus (≥ 4 cm). Two patients with localized prostate cancer with large vesical stone underwent simultaneous cystolithotomy and extraperitoneal radical prostatectomy. Their perioperative period was uneventful. Large vesical stones with localized prostate cancer can be easily managed simultaneously by an experienced robotic surgeon. How to cite this article Bora GS, Dogra PN, Singh P. Robotic Management of Localized Adenocarcinoma Prostate with Large Vesical Calculus: A Report of Two Cases. J Postgrad Med Edu Res 2016;50(1):36-38.

scholarly journals Multiparametric MRI for Recurrent Prostate Cancer Post Radical Prostatectomy and Postradiation Therapy

2014 ◽  
Vol 2014 ◽  
pp. 1-23 ◽  
Author(s):  
Flavio Barchetti ◽  
Valeria Panebianco
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Local Recurrence ◽  
Locoregional Recurrence ◽  
Multiparametric Mri ◽  
Cochrane Library ◽  
Published Data ◽  
Detection And Localization ◽  
The Impact

The clinical suspicion of local recurrence of prostate cancer (PCa) after radical prostatectomy (RP) and after radiation therapy (RT) is based on the onset of biochemical failure. The aim of this paper was to review the current role of multiparametric-MRI (mp-MRI) in the detection of locoregional recurrence. A systematic literature search using the Medline and Cochrane Library databases was performed from January 1995 up to November 2013. Bibliographies of retrieved and review articles were also examined. Only those articles reporting complete data with clinical relevance for the present review were selected. This review article is divided into two major parts: the first one considers the role of mp-MRI in the detection of PCa local recurrence after RP; the second part provides an insight about the impact of mp-MRI in the depiction of locoregional recurrence after RT (interstitial or external beam). Published data indicate an emerging role for mp-MRI in the detection and localization of locally recurrent PCa both after RP and RT which represents an information of paramount importance to perform focal salvage treatments.

The impact of high initial PSA (≥50 ng/ml) at the time of radical prostatectomy for clinically localized prostate cancer on cancer specific survival

2019 ◽  
Vol 18 (1) ◽  
pp. e2052
Author(s):  
P. Mandel ◽  
S. Knipper ◽  
F. Chun ◽  
T. Steuber ◽  
H. Huland ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Localized Prostate Cancer ◽  
Cancer Specific Survival ◽  
The Impact
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