Are psychiatric disorders associated with worse asthma control and quality of life in asthma patients?

Abstract Background Poorly controlled bronchial asthma limits patients’ quality of life (QOL), the condition which may potentiate the development of psychiatric disorders. The aim of this study was the assessment of anxiety and depression in bronchial asthma patients, and their interrelation with both level of asthma control and quality of life in our society. Results This study included 102 bronchial asthma patients, and 50 healthy control individuals. Patients had poorer QOL, and higher anxiety and depression scores compared to healthy control, moreover these scores were higher in uncontrolled asthma patients compared to controlled group. Poor QOL, frequent hospital admissions, and poor asthma control were the predictors for psychiatric disorders. Conclusion Depression and anxiety are frequently encountered in patients with bronchial asthma in our society; poor symptom control, poor QOL, and frequent hospital admissions are the main predictors for these psychiatric disorders.

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Assessment of quality of life in asthma patients in 5 to 18 years of children

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20204549 ◽

2020 ◽

Vol 7 (11) ◽

pp. 2214

Author(s):

Nikhil Jain ◽

Karan Joshi

Keyword(s):

Quality Of Life ◽

Asthma Control ◽

Persistent Asthma ◽

Tertiary Hospital ◽

P Value ◽

Cross Sectional ◽

Asthmatic Patients ◽

Asthma Patients ◽

Severity Of The Disease

Background: Asthma is a common cause of morbidity and mortality with prevalence of 300 million in world. The QOL of asthmatic patients cannot be determined only on the basis the severity of the disease, but requires a measurement of personal perception. This study was conducted with the aim to assess and compare the QOL using PedsQl scale in asthma patients between 5 to 18 years of age with different demographic and clinical variables.Methods: This was a cross-sectional observational study conducted at respiratory clinic in tertiary hospital, Rewa from October 2017 to June 2019. A total number of 150 asthmatic patients and their parents participated. Asthmatic patients (N=150) and their parents, presenting to asthma clinic of Gandhi Memorial Hospital, Rewa (after applying inclusion-exclusion criteria) were assessed for QOL using PedsQl scale 3.0. Statistical analysis was performed by SPSS version 20. Test of significance by student T-test and one way ANOVA.Results: The QOL is severely hampered by asthma with mean of 59 in intermittent asthma, 51 in mild, 44.74 in moderate and 40 in severe persistent asthma, significant p value of <0.05. Younger age, level of asthma control and severity were significantly related to QOL with p value of <0.05. Sex, socioeconomic status, were insignificantly related.Conclusions: QOL is impaired as the grading of asthma increases. Impairment of Quality of life are mostly associated with low level of asthma control, poly-therapy and frequent night attacks.

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Gastroesophageal Reflux Disease Is Associated With Poor Asthma Control, Quality of Life, and Psychological Status in Chinese Asthma Patients

CHEST Journal ◽

10.1378/chest.08-1702 ◽

2009 ◽

Vol 135 (5) ◽

pp. 1181-1185 ◽

Cited By ~ 23

Author(s):

Ting Kin Cheung ◽

Bing Lam ◽

Kam Fai Lam ◽

Mary Ip ◽

Connie Ng ◽

...

Keyword(s):

Quality Of Life ◽

Gastroesophageal Reflux Disease ◽

Gastroesophageal Reflux ◽

Asthma Control ◽

Reflux Disease ◽

Psychological Status ◽

Control Quality ◽

Asthma Patients

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Factors affecting asthma psychomorbidity, control and illness-related quality of life: what is the interaction?

European Psychiatry ◽

10.1016/s0924-9338(11)73449-6 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 1745-1745

Author(s):

N. Pilipenko ◽

M. Karekla

Keyword(s):

Quality Of Life ◽

Asthma Control ◽

Research Literature ◽

Smoking History ◽

Inflammatory Disorder ◽

Chronic Inflammatory Disorder ◽

Asthma Patients ◽

Related Quality ◽

The Impact

Asthma is a chronic inflammatory disorder of the airways, ounknown etiology and growing prevalence (GINA, 2009). Appropriate asthma management can control the disorder and enable patients to enjoy a good quality of life (WHO, 2007).Yet, many asthma patients are unable to maintain asthma control (Rabe et al., 2003) for various reasons, including psychological ones (Feldman et al., 2005).This study examined the prevalence of psychomorbidity, and its interaction with asthma control difficulties and asthma-related quality of life in a sample of 200 asthma patients in Cyprus. Asthma diagnoses and severity were established by medical chart review.Psychomorbidity was evaluated using the Patient Health Questionnaire (Spitzer, 1999). Additionally, the impact of asthma-specific (e.g. asthma knowledge), health-specific (e.g. smoking history) and socio-demographic (e.g. perceived poverty) factors was examined as prior research literature suggests these may significantly impact asthma control and asthma-related quality of life.Currently, the present study is in its final stages of data collection (to conclude 2010). The results will offer valuable insights into the mechanisms and factors which affect asthma control, quality of life, and psychomorbidity. In doing so, the present study will contribute to the improved understanding of asthma patients’ experiences, essential to guide medical and psychological interventions.

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A 1-day visit in a severe asthma centre: effect on asthma control, quality of life and healthcare use

European Respiratory Journal ◽

10.1183/13993003.00220-2016 ◽

2016 ◽

Vol 48 (3) ◽

pp. 726-733 ◽

Cited By ~ 36

Author(s):

Akke-Nynke van der Meer ◽

Henk Pasma ◽

Wilma Kempenaar-Okkema ◽

Jo-Anneke Pelinck ◽

Myrte Schutten ◽

...

Keyword(s):

Quality Of Life ◽

Asthma Control ◽

Severe Asthma ◽

Life Questionnaire ◽

Healthcare Use ◽

Uncontrolled Asthma ◽

Control Quality ◽

Asthma Patients

Patients with uncontrolled asthma report ongoing symptoms, poor quality-of-life and extensive healthcare use (HCU) and might benefit from management by a specialised severe asthma team. It is unknown whether a one-time evaluation by asthma experts, without long-term supervision by a specialised team, provides favourable outcomes. We evaluated asthma control (Asthma Control Questionnaire; ACQ), quality-of-life (Asthma-related Quality of Life Questionnaire; AQLQ) and HCU before and 1 year after a 1-day visit programme in a severe asthma centre, including a multidisciplinary assessment resulting in a personalised management plan to be implemented by patients own pulmonologists.40 uncontrolled asthma patients completed questionnaires (ACQ, AQLQ, HCU) at baseline, and 6 and 12 months follow-up.ACQ improved from 2.6 (interquartile range 1.7–3.2) to 1.8 (1.2–3.2) (p=0.003) and AQLQ from 4.8 (4.0–5.2) to 5.3 (4.4–6.0) (p<0.001). We found a reduction in patients with ≥2 exacerbations (95% versus 17%; p<0.001), ≥1 emergency room visit (78% versus 37%; p<0.001) and ≥1 hospitalisation (47% versus 10%; p=0.001).Evaluation of uncontrolled asthma patients in a 1-day visit programme in a severe asthma centre resulted in significant improvements in asthma control, quality-of-life and healthcare use after 1 year. This 1-day visit approach seems beneficial for uncontrolled asthma patients and might reduce their dependence on expensive treatment modalities and long-term management in specialised centres.

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Dupilumab Improves Asthma Control and Asthma-Related Quality of Life in Uncontrolled Persistent Asthma Patients Across All Baseline Exacerbation Rates

CHEST Journal ◽

10.1016/j.chest.2017.08.056 ◽

2017 ◽

Vol 152 (4) ◽

pp. A26 ◽

Cited By ~ 3

Author(s):

Jonathan Corren ◽

Mario Castro ◽

Shyamalie Jayawardena ◽

Vijay Joish ◽

Nikhil Amin ◽

...

Keyword(s):

Quality Of Life ◽

Asthma Control ◽

Persistent Asthma ◽

Asthma Patients ◽

Related Quality

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Study of quality of life in epilepsy patients with psychiatric co-morbidities using QOLIE-31

International Journal of Epilepsy ◽

10.1016/j.ijep.2014.05.004 ◽

2014 ◽

Vol 01 (01) ◽

pp. 008-015

Author(s):

Gujjar Amruth ◽

Praveen-kumar Srikanteswara ◽

Boraiah Nataraju ◽

Pandiyan Kasturi

Keyword(s):

Quality Of Life ◽

Developing Countries ◽

Psychiatric Disorders ◽

Asthma Control ◽

Age Groups ◽

Published Data ◽

Control Subjects ◽

Patients With Epilepsy ◽

Morbid Conditions

AbstractBackground Epilepsy is a neurological condition affecting both the sexes in all age groups and is associated with psychiatric co-morbid conditions. There is a paucity of available published data regarding psychiatric co-morbid conditions and quality of life in patients with Epilepsy (PWE) from developing countries.Methods We evaluated the quality of life in 80 PWE, 80 with asthma (asthma control subjects: AC) and 80 normal healthy patients (normal control subjects: NC) using the QOLIE-31 item inventory.Results Psychiatric co-morbid conditions are more common in PWE (32.50%) as compared to the AC (17.5%) and NC (7.5%). The quality of life in PWE was significantly lower when compared to control subjects and it was further low in the presence of co-morbid psychiatric disorders.Conclusion Co-morbid psychiatric disorders should be identified and documented in PWE and treating these disorders apart from the control of seizures may significantly improve their quality of life.

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Is ventilation heterogeneity related to asthma control?

European Respiratory Journal ◽

10.1183/13993003.00393-2016 ◽

2016 ◽

Vol 48 (2) ◽

pp. 370-379 ◽

Cited By ~ 33

Author(s):

Sarah Svenningsen ◽

Parameswaran Nair ◽

Fumin Guo ◽

David G. McCormack ◽

Grace Parraga

Keyword(s):

Quality Of Life ◽

Asthma Control ◽

Forced Expiratory Volume ◽

Life Questionnaire ◽

Strongly Correlated ◽

Asthma Control Questionnaire ◽

Asthma Patients ◽

Ventilation Heterogeneity ◽

Magnetic Resonance Imaging Mri

In asthma patients, magnetic resonance imaging (MRI) and the lung clearance index (LCI) have revealed persistent ventilation heterogeneity, although its relationship to asthma control is not well understood. Therefore, our goal was to explore the relationship of MRI ventilation defects and the LCI with asthma control and quality of life in patients with severe, poorly controlled asthma.18 patients with severe, poorly controlled asthma (mean±sd 46±12 years, six males/12 females) provided written informed consent to an ethics board approved protocol, and underwent spirometry, LCI and 3He MRI during a single 2-h visit. Asthma control and quality of life were evaluated using the Asthma Control Questionnaire (ACQ) and Asthma Quality of Life Questionnaire (AQLQ). Ventilation heterogeneity was quantified using the LCI and 3He MRI ventilation defect percent (VDP).All participants reported poorly controlled disease (mean±sd ACQ score=2.3±0.9) and highly heterogeneous ventilation (mean±sd VDP=12±11% and LCI=10.5±3.0). While VDP and LCI were strongly correlated (r=0.86, p<0.0001), in a multivariate model that included forced expiratory volume in 1 s, VDP and LCI, VDP was the only independent predictor of asthma control (R2=0.38, p=0.01). There was also a significantly worse VDP, but not LCI in asthma patients with an ACQ score >2 (p=0.04) and AQLQ score <5 (p=0.04), and a trend towards worse VDP (p=0.053), but not LCI in asthma patients reporting ≥1 exacerbation in the past 6 months.In patients with poorly controlled, severe asthma MRI ventilation, but not LCI was significantly worse in those with worse ACQ and AQLQ.

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Correlation of illness perception, asthma control, and lung function value to the quality of life of asthma outpatients

Farmasains Jurnal Farmasi dan Ilmu Kesehatan ◽

10.22219/farmasains.v4i1.10176 ◽

2019 ◽

Vol 4 (1) ◽

pp. 43

Author(s):

Nadia Aisah Mayzika ◽

Asri Wido Mukti

Keyword(s):

Quality Of Life ◽

Lung Function ◽

Asthma Control ◽

Illness Perception ◽

Life Quality ◽

Equation Modeling ◽

Asthmatic Patients ◽

Asthma Patients ◽

The Relationship

Asthma is a heterogeneous disease and chronic inflammation of the respiratory tract that has an impact on the decreased quality of life. The design of this research is non-experimental cross-sectional. The variables of this study are illness perception, control of asthma, lung function values, and life quality of asthma patients. The relationship of asthma control, illness perception, lung function value, and life quality of asthma patients can be seen with structural equation modeling using Smart-PLS software. The results are only control of asthma affects life quality, where the coefficient value is 0.511, which is positive and significant (p = 0,000). Lung function value and asthma quality indicate that lung function has a positive relationship direction seen from the coefficient value of 0.306 but not significant (p = 0.061). The correlation between illness perception and life quality of asthma was negative, where the coefficient value was - 0.142 and not significantly different (p = 0.332). This means that the direction of the relationship is reversed; it means the quality of life of asthmatic patients, which affects illness perception by 14.2%. The conclusion is that the life quality of asthmatic patients is influenced by the control of asthma and lung function. But it’s different from illness perception, where there is a negative relationship between illness perception and life quality of asthma patients. Which means illness perception affects the life quality of asthma patients.

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