Research infrastructure

Author(s):  
Athula Sumathipala
2009 ◽  
Vol 2 (1) ◽  
pp. 27-32
Author(s):  
Andrew Storer

Consensus groups believe that clinical research networks are a more effective method of conducting clinical research than stand-alone sites. For example, clinical research networks have increased patient recruitment, decreased financial overhead, and allowed for coordinated research efforts, resulting in decreased duplication within high-cost research infrastructure. To date, there is little evidence describing the benefits and effectiveness of clinical research networks.


Atmosphere ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 868
Author(s):  
Jonathan Durand ◽  
Edouard Lees ◽  
Olivier Bousquet ◽  
Julien Delanoë ◽  
François Bonnardot

In November 2016, a 95 GHz cloud radar was permanently deployed in Reunion Island to investigate the vertical distribution of tropical clouds and monitor the temporal variability of cloudiness in the frame of the pan-European research infrastructure Aerosol, Clouds and Trace gases Research InfraStructure (ACTRIS). In the present study, reflectivity observations collected during the two first years of operation (2016–2018) of this vertically pointing cloud radar are relied upon to investigate the diurnal and seasonal cycle of cloudiness in the northern part of this island. During the wet season (December–March), cloudiness is particularly pronounced between 1–3 km above sea level (with a frequency of cloud occurrence of 45% between 12:00–19:00 LST) and 8–12 km (with a frequency of cloud occurrence of 15% between 14:00–19:00 LST). During the dry season (June–September), this bimodal vertical mode is no longer observed and the vertical cloud extension is essentially limited to a height of 3 km due to both the drop-in humidity resulting from the northward migration of the ITCZ and the capping effect of the trade winds inversion. The frequency of cloud occurrence is at its maximum between 13:00–18:00 LST, with a probability of 35% at 15 LST near an altitude of 2 km. The analysis of global navigation satellite system (GNSS)-derived weather data also shows that the diurnal cycle of low- (1–3 km) and mid-to-high level (5–10 km) clouds is strongly correlated with the diurnal evolution of tropospheric humidity, suggesting that additional moisture is advected towards the island by the sea breeze regime. The detailed analysis of cloudiness observations collected during the four seasons sampled in 2017 and 2018 also shows substantial differences between the two years, possibly associated with a strong positive Indian Ocean Southern Dipole (IOSD) event extending throughout the year 2017.


2020 ◽  
Vol 27 (3) ◽  
pp. 213-231
Author(s):  
Annagrazia Altavilla ◽  
Viviana Giannuzzi ◽  
Mariangela Lupo ◽  
Donato Bonifazi ◽  
Adriana Ceci

Abstract The lack of paediatric medicines, including innovative and advanced ones, is a long-lasting and well-known problem at European and international levels. Despite the existing legal frameworks and incentives, children remain deprived of many kinds of therapy because of challenges faced in appropriately study and tailoring medicinal and other products for them. In this context, the necessity to foster paediatric research addressing unsolved and uncovered issues within a ‘translational approach’ has appeared. This article, after having clarified the concept of translational research in the perspective of the establishment of a European paediatric research infrastructure (RI), will identify and point out ethical, legal and regulatory issues particularly relevant in a children’s rights perspective. It concludes asking for the setting up of an adequate model of governance within a future RI, including adequate and independent ethical oversight and a pluridisciplinary common service dealing with ethical, legal and societal issues relevant for children.


2016 ◽  
Vol 44 (4) ◽  
pp. 327-337 ◽  
Author(s):  
Mohsen Kalantari ◽  
Abbas Rajabifard ◽  
Hamed Olfat ◽  
Chris Pettit ◽  
Azadeh Keshtiarast

Author(s):  
I. Dezhina ◽  
N. Sheliubskaya

The article describes the results of the inventory of the unique research equipment conducted by IMEMO RAS in 2009-2010 as an order from the Ministry of Education and Science of the RF. The methodology used for the survey was partially based on the EC experience which is also presented in the article. The results of the analysis suggest that the unique equipment is more actively used in RAS institutes rather than in universities. However the speed at which equipment is renewed is higher at universities, due to the special government policy. The most severe problems related to support of unique infrastructure are associated with the lack of financing and resources for technical maintenance. In conclusions possible directions for improvement of the government policy towards research infrastructure are outlined.


2021 ◽  
Author(s):  
Andreas Petzold ◽  
Valerie Thouret ◽  
Christoph Gerbig ◽  
Andreas Zahn ◽  
Martin Gallagher ◽  
...  

<p>IAGOS (www.iagos.org) is a European Research Infrastructure using commercial aircraft (Airbus A340, A330, and soon A350) for automatic and routine measurements of atmospheric composition including reactive gases (ozone, carbon monoxide, nitrogen oxides, volatile organic compounds), greenhouse gases (water vapour, carbon dioxide, methane), aerosols and cloud particles along with essential thermodynamic parameters. The main objective of IAGOS is to provide the most complete set of high-quality essential climate variables (ECV) covering several decades for the long-term monitoring of climate and air quality. The observations are stored in the IAGOS data centre along with added-value products to facilitate the scientific interpretation of the data. IAGOS began as two European projects, MOZAIC and CARIBIC, in the early 1990s. These projects demonstrated that commercial aircraft are ideal platforms for routine atmospheric measurements. IAGOS then evolved as a European Research Infrastructure offering a mature and sustainable organization for the benefits of the scientific community and for the operational services in charge of air quality and climate change issues such as the Copernicus Atmosphere Monitoring Services (CAMS) and the Copernicus Climate Change Service (C3S). IAGOS is also a contributing network of the World Meteorological Organization (WMO).</p> <p>IAGOS provides measurements of numerous chemical compounds which are recorded simultaneously in the critical region of the upper troposphere – lower stratosphere (UTLS) and geographical regions such as Africa and the mid-Pacific which are poorly sampled by other means. The data are used by hundreds of groups worldwide performing data analysis for climatology and trend studies, model evaluation, satellite validation and the study of detailed chemical and physical processes around the tropopause. IAGOS data also play an important role in the re-assessment of the climate impact of aviation.</p> <p>Most important in the context of weather-related research, IAGOS and its predecessor programmes provide long-term observations of water vapour and relative humidity with respect to ice in the UTLS as well as throughout the tropospheric column during climb-out and descending phases around airports, now for more than 25 years. The high quality and very good resolution of IAGOS observations of relative humidity over ice are used to better understand the role of water vapour and of ice-supersaturated air masses in the tropopause region and to improve their representation in numerical weather and climate forecasting models. Furthermore, CAMS is using the water vapour vertical profiles in near real time for the continuous validation of the CAMS atmospheric models. </p>


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