scholarly journals n-3 Fatty acids, cancer and cachexia: a systematic review of the literature

2007 ◽  
Vol 97 (5) ◽  
pp. 823-831 ◽  
Author(s):  
Ramón Colomer ◽  
José M. Moreno-Nogueira ◽  
Pedro P. García-Luna ◽  
Pilar García-Peris ◽  
Abelardo García-de-Lorenzo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Fatty Acids ◽  
Advanced Cancer ◽  
Review Of The Literature ◽  
Surgical Morbidity ◽  
Patients With Cancer ◽  
Length Of Treatment ◽  
Hospital Stays ◽  
Cancer Setting ◽  
Oral Supplements

Use of n-3 fatty acids (FA) has been reported to be beneficial for cancer patients. We performed a systematic review of the literature in order to issue recommendations on the clinical use of n-3 FA in the cancer setting. A systematic search was performed in MEDLINE, EMBASE, Cochrane and Healthstar databases. We selected clinical trials or prospective observational studies including patients with cancer and life expectancy >2 months, in which enteral supplements with n-3 FA were administered. Parameters evaluated individually were clinical (nutritional status, tolerance, survival and hospital stays), biochemical (inflammatory mediators), and functional (functional status, appetite and quality of life (QoL)). Seventeen studies met the inclusion criteria; eight were of high quality. The panel of experts established the following evidence: (1) oral supplements with n-3 FA benefit patients with advanced cancer and weight loss, and are indicated in tumours of the upper digestive tract and pancreas; (2) the advantages observed were: increased weight and appetite, improved QoL, and reduced post-surgical morbidity; (3) there is no defined pattern for combining different n-3 FA, and it is recommended to administer >1·5 g/day; and (4) better tolerance is obtained administering low-fat formulas for a period of at least 8 weeks. All the evidences were grade B but for ‘length of treatment’ and ‘advantage of survival’ it was grade C. Our findings suggest that administration of n-3 FA (EPA and DHA) in doses of at least 1·5 g/day for a prolonged period of time to patients with advanced cancer is associated with an improvement in clinical, biological and QoL parameters.

scholarly journals An assessment of the use of patient reported outcome measurements (PROMs) in cancers of the pelvic abdominal cavity: identifying oncologic benefit and an evidence-practice gap in routine clinical practice

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Miss Charlotte L. Moss ◽  
Ajay Aggarwal ◽  
Asad Qureshi ◽  
Benjamin Taylor ◽  
Teresa Guerrero-Urbano ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Abdominal Cavity ◽  
Patient Reported Outcome ◽  
Oncologic Outcomes ◽  
Review Of The Literature ◽  
Outcome Measurements ◽  
Patient Reported ◽  
Cancer Setting

Abstract Background Patient reported outcome measurements (PROMs) are emerging as an important component of patient management in the cancer setting, providing broad perspectives on patients’ quality of life and experience. The use of PROMs is, however, generally limited to the context of randomised control trials, as healthcare services are challenged to sustain high quality of care whilst facing increasing demand and financial shortfalls. We performed a systematic review of the literature to identify any oncological benefit of using PROMs and investigate the wider impact on patient experience, in cancers of the pelvic abdominal cavity specifically. Methods A systematic review of the literature was conducted using MEDLINE (Pubmed) and Ovid Gateway (Embase and Ovid) until April 2020. Studies investigating the oncological outcomes of PROMs were deemed suitable for inclusion. Results A total of 21 studies were included from 2167 screened articles. Various domains of quality of life (QoL) were identified as potential prognosticators for oncologic outcomes in cancers of the pelvic abdominal cavity, independent of other clinicopathological features of disease: 3 studies identified global QoL as a prognostic factor, 6 studies identified physical and role functioning, and 2 studies highlighted fatigue. In addition to improved outcomes, a number of included studies also reported that the use of PROMs enhanced both patient-clinician communication and patient satisfaction with care in the clinical setting. Conclusions This review highlights the necessity of routine collection of PROMs within the pelvic abdominal cancer setting to improve patient quality of life and outcomes.

The risk of rash associated with ipilimumab in patients with cancer: A systematic review of the literature and meta-analysis

2013 ◽  
Vol 69 (3) ◽  
pp. e121-e128 ◽  
Author(s):  
Kira Minkis ◽  
Benjamin C. Garden ◽  
Shenhong Wu ◽  
Melissa P. Pulitzer ◽  
Mario E. Lacouture
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Review Of The Literature ◽  
Patients With Cancer

scholarly journals Antipsychotic-induced akathisia in delirium: A systematic review

2015 ◽  
Vol 14 (1) ◽  
pp. 77-84 ◽  
Author(s):  
Fernando Espi Forcen ◽  
Konstantina Matsoukas ◽  
Yesne Alici
Keyword(s):  
Systematic Review ◽  
Side Effect ◽  
Atypical Antipsychotics ◽  
Medical Literature ◽  
Common Side Effect ◽  
Related Phenomenon ◽  
Review Of The Literature ◽  
Antipsychotic Medications ◽  
Patients With Cancer ◽  
Current State

AbstractObjective:Akathisia is a neuropsychiatric syndrome characterized by subjective and objective restlessness. It is a common side effect in patients taking antipsychotics and other psychotropics. Patients with delirium are frequently treated with antipsychotic medications that are well known to induce akathisia as a side effect. However, the prevalence, phenomenology, and management of akathisia in patients with delirium remain largely unknown. The purpose of this review was to examine the medical literature in order to establish the current state of knowledge regarding the prevalence of antipsychotic-induced akathisia in patients with delirium.Method:A systematic review of the literature was conducted using the EMBASE, MEDLINE, PsycINFO, and CINAHL databases. Ten studies addressing the incidence of akathisia in patients taking antipsychotic medication for delirium were identified and included in our review.Results:The included studies reported a variable prevalence of antipsychotic-induced akathisia. A higher prevalence was found in patients taking haloperidol. Among atypical antipsychotics, paliperidone and ziprasidone were associated with a higher risk of akathisia. The risk for akathisia appeared to be a dose-related phenomenon.Significance of results:Studies using specific scales for evaluation of akathisia in delirium are lacking. Some populations, such as patients with cancer or terminally ill patients in palliative care settings taking antipsychotics for the treatment of delirium, could be at higher risk for development of akathisia as a side effect.

scholarly journals Psychosocial interventions for patients with advanced cancer – a systematic review of the literature

2004 ◽  
Vol 91 (6) ◽  
pp. 1050-1062 ◽  
Author(s):  
R J Uitterhoeve ◽  
M Vernooy ◽  
M Litjens ◽  
K Potting ◽  
J Bensing ◽  
...  
Keyword(s):  
Systematic Review ◽  
Advanced Cancer ◽  
Psychosocial Interventions ◽  
Review Of The Literature

Sociodemographic, socioeconomic, and clinical determinants of survival in patients with cancer: A systematic review of the literature focused on the elderly

2018 ◽  
Vol 9 (1) ◽  
pp. 6-14 ◽  
Author(s):  
Angéline Galvin ◽  
Fleur Delva ◽  
Catherine Helmer ◽  
Muriel Rainfray ◽  
Carine Bellera ◽  
...  
Keyword(s):  
Systematic Review ◽  
The Elderly ◽  
Review Of The Literature ◽  
Patients With Cancer

scholarly journals Quality Measures for Palliative Care in Patients With Cancer: A Systematic Review

2014 ◽  
Vol 10 (4) ◽  
pp. 281-287 ◽  
Author(s):  
Arif H. Kamal ◽  
Margaret Gradison ◽  
Jennifer M. Maguire ◽  
Donald Taylor ◽  
Amy P. Abernethy
Keyword(s):  
Systematic Review ◽  
Palliative Care ◽  
Adverse Effects ◽  
Advanced Cancer ◽  
Quality Measures ◽  
Social Distress ◽  
Patients With Cancer

Within quality measures for palliative care, there is often a focus on symptoms and adverse effects of therapy; little attention is given to other aspects of suffering observed in patients with advanced cancer, such as psychological and social distress.

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