scholarly journals The effect of glucose infusion on the plasma free amino acids in sheep

1975 ◽  
Vol 34 (3) ◽  
pp. 375-382 ◽  
Author(s):  
N. W. Offer ◽  
M. V. Tas ◽  
R. F. E. Axford ◽  
R. A. Evans

1. Glucose in solution in saline, or saline alone, was administered to a group of twenty ewes during late pregnancy and again after lambing. Sequential blood samples were taken before and after the infusion and the concentration of plasma free amino acids was determined.2. The effect of glucose was to reduce the concentrations of all amino acids except alanine. The reduction was greatest for tryptophan in the pregnant sheep, but this amino acid showed no significant change in the lactating animals.3. An attempt to rank the amino acids on the basis of their response to glucose infusion indicated that, with the exception of tryptophan for the preparturient ewes, groups of essential amino acids could not be distinguished from each other. These groups were, for the preparturient sheep, valine, leucine, phenylalanine and isoleucine, and for the postparturient animals, isoleucine, lysine, methionine, valine and phenylalanine.

1968 ◽  
Vol 22 (1) ◽  
pp. 9-20 ◽  
Author(s):  
V. R. Young ◽  
N. S. Scrimshaw

1. Variation in endogenous nitrogen metabolism was determined by giving eleven healthy men, aged 17–22, a diet supplying daily only 6 mg N/kg body-weight. Eight subjects were given the diet for 7–10 days and three other subjects were given it for 16 days.2. Body cell mass (BCM) was calculated from whole-body 40K in ten subjects and basal metabolism was determined in seven subjects during the ‘protein-free’ period. Urine was analysed daily for N and creatinine, and faecal N was measured in pooled samples. Plasma free amino acids, serum albumin and protein were measured in preprandial morning blood samples at the beginning and end of the study.3. BCM did not change during the ‘protein-free’ period and accounted for 48% of the total body-weight. Basal calorie expenditure amounted to 48 ± 5 kcal/kg BCM per day.4. Mean daily endogenous urinary N excretion in the eight subjects given the ‘protein-free’ diet for 7–10 days was 36·6 ± 3·0 mg N/kg body-weight, 79·4 ± 4·4 mg N/kg BCM and 1·6 ± 0·2 mg N/basal kcal. Endogenous faecal N excretion was 9·9 ± 1·1 mg N/kg body-weight and accounted for 20% of the total endogenous loss. Results obtained with three other subjects given the diet for 16 days were similar.5. Plasma essential amino acids were reduced, glutamic acid, alanine and glycine increased, and the ratio of essential to non-essential amino acids decreased after 7 or 10 days of ‘protein-free’ diet.6. The loss of endogenous N per basal kcal and of faecal N per kg body-weight was lower than the values assumed in the factorial approach to protein requirements by the FAO/WHO (1965) Expert Group on Protein Requirements.


1974 ◽  
Vol 16 (1) ◽  
pp. 54-54
Author(s):  
Teruo Honda ◽  
Naoya Morishima ◽  
Tetsuhiko Matsuno ◽  
Toshihiko Sasaki

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
MH Mahbub ◽  
Natsu Yamaguchi ◽  
Hidekazu Takahashi ◽  
Ryosuke Hase ◽  
Yasutaka Ishimaru ◽  
...  

PEDIATRICS ◽  
1984 ◽  
Vol 73 (6) ◽  
pp. 879-879
Author(s):  
T. A. TEDESCO ◽  
S. A. BENFORD ◽  
R. C. FOSTER ◽  
L. A. BARNESS

To the Editor.— Currently accepted dietary management of citrullinemia and other urea cycle disorders includes protein restriction, sodium benzoate, and dietary supplements of keto acids or essential amino acids with postblock intermediates such as arginine in citrullinemia and arginino-succinic aciduria. When a child survives the neonatal period on such a regimen and solid foods are introduced into the diet, there is at least one fruit that should be avoided, Citrullus Vulgaris, commonly known as watermelon. Quantitation of free amino acids extracted from 1 g wet weight of watermelon fruit yielded the following (in mmoles per gram wet weight): Phenylalanine, 1.25; histidine, 0.24; tryptophan, 0.35; lysine, 0.82; ornithine, 0.32; arginine, 11.36; aspartic acid, 0.97; threonine, 0.74; serine, 1.05; glutamine, 3.86; glutamic acid, 1.38; citrulline, 23.68; alanine, 1.15; valine, 0.17; isoleucine, 1.24; leucine, 0.24.


1975 ◽  
Vol 8 (1-6) ◽  
pp. 303-306 ◽  
Author(s):  
A. Mannan ◽  
L.I. Wiebe ◽  
A.A. Noujaim ◽  
D.C. Secord

1990 ◽  
Vol 188 (2) ◽  
pp. 101-108 ◽  
Author(s):  
I. Ceballos ◽  
P. Chauveau ◽  
V. Guerin ◽  
J. Bardet ◽  
P. Parvy ◽  
...  

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