Genetic Research, Family Life, and Clinical Practice

1998 ◽  
Vol 39 (3) ◽  
pp. 291-305 ◽  
Author(s):  
Martin Richards
2005 ◽  
Vol 20 (2) ◽  
pp. 131-138 ◽  
Author(s):  
Alexandra E. Shields ◽  
David Blumenthal ◽  
Kevin B. Weiss ◽  
Catherine B. Comstock ◽  
Douglas Currivan ◽  
...  

2009 ◽  
Vol 15 (1) ◽  
pp. 23-31 ◽  
Author(s):  
Martin Curtice

SummaryThe Human Rights Act was introduced into UK law in 2000 and must be considered in all cases, including mental health review tribunals. Article 8 (the right to respect for private and family life) comprises two parts and has embedded in it ‘tests’ that must be applied when assessing any interference with this protected right. A review of Article 8 case law reveals how it is used and how it can be applied in a myriad of clinical situations. Because it involves the right to respect for private life, and is in a sense individualised, it will potentially affect people (both patients and staff) in the mental health services in a variety of ways. Article 8 has implications not only for patients but also for clinicians and healthcare organisations.


2007 ◽  
Vol 23 (2) ◽  
pp. 162-168 ◽  
Author(s):  
Kirsten F. L. Douma ◽  
Kim Karsenberg ◽  
Marjan J. M. Hummel ◽  
Jolien M. Bueno-de-Mesquita ◽  
Wim H. van Harten

Objectives: Technologies in health care are evolving quickly, with new findings in the area of biotechnological and genetic research being published regularly. A health technology assessment (HTA) is often used to answer the question of whether the new technology should be implemented into clinical practice. International evidence confirms that the results of HTA research sometimes have limited impact on practical implementation and on coverage decisions; the study design is commonly based on the paradigm of stability of both the technology and the environment, which is often not the case. Constructive technology assessment (CTA) was first described in the 1980s. In addition to the traditional HTA elements, this approach also takes into account the technology dynamics by emphasizing sociodynamic processes. With a CTA approach, comprehensive assessment can be combined with an intentional influence in a favorable direction to improve quality.Methods: In this study, the methodological aspects mainly concerning the diagnostic use of CTA are explained. The methodology will be illustrated using the controlled introduction of a new technology, called microarray analysis, into the clinical practice of breast cancer treatment as a case study. Attention is paid to the operationalization of the phases of development and implementation and the research methods most appropriate for CTA.Conclusions: In addition to HTA, CTA can be used as a complementary approach, especially in technologies that are introduced in an early stage of development in a controlled way.


1997 ◽  
Vol 46 (3) ◽  
pp. 139-146
Author(s):  
B. Dallapiccola ◽  
I. Torrente ◽  
R. Mingarelli ◽  
G. Novelli

AbstractThe present genome era is characterized by speedy progress and prompt transfer of results into clinical practice. This creates the need for rapid disclosure of results and renewal of laboratory's protocols. Molecular cytogenetics has provided and increased ability to identify chromosomes, correlate chromosome structure with gene location, find out cryptic aberrations, and detect specific DNA sequences. These advances have allowed the confident discovery of a number of contiguous gene syndromes. The positional cloning and positional candidate strategies have greatly expedited the search process of disease genes, and become relevant methods for genes' discovery. Understanding the molecular basis of diseases has shown an unpredicted wide genetic heterogeneity, which has splitted single disorders into many clinically similar conditions, and added complexity to the nosology of human diseases. The opposite process, allelism, where clinical diversity results from allelic mutations, has lumped together many distinct disorders, by showing that different clinical entities are not necessarily due to mutations in different genes. Dynamic mutations have provided the molecular understanding of interindividual and intrafamilial variability including anticipation, in a number of diseases. The discovery of distinct correlations between the molecular pattern and disease severity is providing a unique opportunity for using molecular results to assess the clinical outcome. Diagnostic, presymptomatic and predictive molecular testing are becoming widely used and provide enormous opportunities for improving the lot of our patients.


1991 ◽  
Vol 8 (1) ◽  
pp. 40-42
Author(s):  
Elizabeth A. Dunne ◽  
Aine Melinn ◽  
Tony Humphreys ◽  
Ethel Quayle

AbstractA group of psychiatric nurses (N = 15) rated the impact of participation in a one year post-experience training course in behavioural psychotherapy on their personal/family life; professional practice; and professional relationships. Levels of stress associated with different phases of the course were also monitored.Results indicated that the main stresses were associated with re-adjustment of family life over the period of the course and ensuring stability of training placements at the outset of the course. The course fulfilled participants' expectations with regard to improving their clinical practice, and confirmed their view that relationships with psychiatrist colleagues would be unaffected by their participation on the course. Impact on relationships with nurse colleagues was more positive than had been anticipated during the period of the course.


This paper attempts to correct the unwitting reliance of much transpersonal psychology upon Indian texts that were indigenously specific to sannyasins (nonhouseholder, monastics). This includes teachings from advaita vedanta, yoga, and many Buddhist schools on releasement from desire, the diminishing role of the ego, guardedness toward “the mellow-drama” of “worldly” life (as Ram Dass famously cast relational involvements). Some forty years of the unwitting over-application of such teachings to modern non-monastic lives has helped create an artificial split in transpersonal and East-West spirituality teachings involving “engaged/ embodied” and implied “un-engaged/un-embodied” spiritual paths. This article describes the value system and lifelong spiritual developmental path of the married householder (grihasthyin), where healthy ambition and egoic traits such as loyalty and lifelong commitment are emphasized en route to a balanced “ego-dissolution” and “ego-development” within the crucible of lifelong marriage, daily family life, and conscious aging. Thus, “spiritual bypass” issues are highly age-specific. Suggestions for a grihasthya-based marriage therapy are also described, drawing from forty-four years of clinical practice, as well as from the two-thousand-yearold Greco-Judeo-Christian soteriological (spiritually-healing) psychology based in admiration, gratitude, longing, apology, and forgiveness.


2018 ◽  
Vol 182 (12) ◽  
pp. i-i

Scott Miller is a familiar face from the popular TV series Vet on the Hill, but balancing the demands of media work with a veterinary career and family life isn’t easy.


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