Fibrous histiocytoma of the larynx

1989 ◽  
Vol 103 (2) ◽  
pp. 216-218 ◽  
Author(s):  
M. B. Jordan ◽  
J. V. Soames
Keyword(s):  
Head And Neck ◽  
Fibrous Histiocytoma ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
Benign Tumour ◽  
Head And Neck Region ◽  
Potentially Malignant

AbstractFibrous histiocytoma is uncommon in the head and neck region and rare in the larynx. Its behaviour is unpredictable.A case is reported in a 54-year-old male which was treated conservatively initially and which recurred several times over a seven year period. During that time the appearances of the lesion changed from those of a densely collagenous, cytologically benign tumour to those of a richly cellular and potentially malignant neoplasm. Laryngectomy was eventually undertaken.

Malignant fibrous histiocytoma of the head and neck region

Head & Neck ◽  
2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
David W. Clark ◽  
Brian A. Moore ◽  
Shreyaskumar R. Patel ◽  
B. Ashleigh Guadagnolo ◽  
Dianna B. Roberts ◽  
...  
Keyword(s):  
Head And Neck ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Neck Region ◽  
Head And Neck Region

scholarly journals The role of immunohistochemistry for diagnosing undifferentiated malignancy in the head and neck region

2019 ◽  
Vol 10 (1) ◽  
pp. 48-53
Author(s):  
Mohammad Sowkat Hossain ◽  
S M Mahbubul Alam ◽  
Sk Md Jaynul Islam ◽  
Wasim Selimul Haque ◽  
Shamoli Yasmin
Keyword(s):  
Head And Neck ◽  
Soft Tissues ◽  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Cervical Lymphadenopathy ◽  
Neck Region ◽  
Histopathological Diagnosis ◽  
Female Ratio ◽  
Head And Neck Region

Background: Undifferentiated tumours in the head and neck region are not uncommon. They can arise from different sites like in mucosa as well as in salivary glands, soft tissues or lymph nodes. Histopathological examination plays a central role in the diagnosis but difficulties arise with some tumours which are poorlydifferentiated due to their high inter- and intra-observer variability. In those cases, immunohistochemistry has greatly assisted to diagnose the tumours that cannot be accurately identified using routine histopathological procedures. The correct histopathological diagnosis is essential especially in case of malignant tumourwhere subsequent specific therapy is required. The aim of this study was to determine the role of immunohistochemistry for diagnosing undifferentiated malignancy in the head and neck region. Methods: This cross-sectional study was conducted during July 2014 to June 2015. A total of 35 Bangladeshi patient’s specimens of head and neck swelling were collected from two renowned laboratories in Dhaka city.These cases were diagnosed as undifferentiated tumour in histopathological examination.Standard protocol was followed for immunohistochemistry.Then primary immunohistochemical panel which included the markers for Epithelial CK (AE1/AE3),mesenchymal marker (Vimentin) and lymphoid marker (LCA) were used.The cases which were not resolved by primary immunohistochemistry panel, the second panel was applied for further sub classification (Desmin, Chromogranin, CK20, CEA, CD20, CD30, HMB45, NSE). Based on interpretation of immunohistochemical findings final diagnoses were made.Data analysis was performed using the Statistical Package for the Social Sciences for Windows version 22.0 (SPSS, Chicago, Illinois, USA). Results: A total of 35 undifferentiated tumorsof head-neck region were studied.The mean age was 46.3±17.6 years and male to female ratio was 4.8:1. The majority 13 (37.1%) patient had cervical lymphadenopathy, 11 (31.4%) had neck mass and 4(11.4%) had in nasal/sinonasal mass.Regarding histopathologicalcell types, round cell was 21 (60.0%), spindle cell 6 (17.1%), pleomorphic cells 6(17.1%) and epithelioid cells 2(5.7%). In initial histopathological examination, majority 25(71.4%) were undifferentiated malignant neoplasm, 8(22.8%) were metastatic undifferentiated carcinoma, 1(2.9%) was pleomorphic sarcoma and the remaining 1(2.9%) had malignant adnexal tumour. By application of immunohistochemistry, most (33, 94.3%) of the cases were resolved and the two cases remained unresolved. Among the resolved cases majority (15, 45.5%) were lymphoma, 4(12.1%) were metastatic carcinoma, 3(9.1%) were Ewing’s sarcoma and malignant melanoma were found in 3(9.1%) cases. Conclusion: This study supports that the immunohistochemical technique has a fundamental role in the investigation of undifferentiated tumour origin, to determine the correct guidance for treatment and improving the prognosis for head and neck tumour patients. Birdem Med J 2020; 10(1): 48-53

Schwannoma of the palatine tonsil

2005 ◽  
Vol 119 (7) ◽  
pp. 570-572 ◽  
Author(s):  
H T Anil ◽  
B V Chandre Gowda ◽  
S Lakshmi ◽  
S R Niveditha
Keyword(s):  
Head And Neck ◽  
Schwann Cells ◽  
Neck Region ◽  
Benign Tumour ◽  
Palatine Tonsil ◽  
Autonomic Nerves ◽  
Head And Neck Region ◽  
The Third ◽  
Acoustic Nerve ◽  
Neural Sheath

Schwannoma is a solitary, benign tumour arising from the neural sheath Schwann cells of the peripheral, cranial or autonomic nerves. In the head and neck region, it occurs most commonly in association with the acoustic nerve within the skull and is rarely found in oral structures. When it is found in oral structures, the tongue is reported to be the favoured site. Schwannoma of the tonsil is extremely rare, with only two cases reported in the literature. We report what is, to our knowledge, the third case of schwannoma of the tonsil, diagnosed by histopathology.

Malignant Fibrous Histiocytoma of the Head and Neck Region

2009 ◽  
Vol 119 (S1) ◽  
pp. S62-S62
Author(s):  
David W. Clark ◽  
Brian A. Moore ◽  
Dianna B. Roberts ◽  
Erich M. Sturgis
Keyword(s):  
Head And Neck ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Neck Region ◽  
Head And Neck Region

scholarly journals Synovial sarcoma of the para pharyngeal space: a case report and literature review

2019 ◽  
Vol 11 (2) ◽  
pp. 116-117
Author(s):  
Anass Chaouki ◽  
Merzouqui B ◽  
Zouhair N ◽  
Beghdad M ◽  
Abada R ◽  
...  
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Synovial Sarcoma ◽  
Clinical Case ◽  
Soft Tissue Sarcomas ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
High Grade ◽  
Head And Neck Region ◽  
Histological Features

Synovial sarcoma (SS) is a malignant neoplasm that arises from primitive pluripotential mesenchymal cells . It is a high-grade histological variety of sarcoma and it accounts for 7-10% of all soft tissue sarcomas. Head and neck locations represent only 0.7% to 10% of all cases. Primary parapharyngeal synovial sarcoma (PPSS) is rare representing only 0.5% of all tumors of the head and neck region. We describe through a clinical case the clinical, radiological and histological features of PPSS and we discuss its therapeutic management.

scholarly journals Myxofibrosarcoma of the sphenoid sinus

2002 ◽  
Vol 116 (6) ◽  
pp. 464-466 ◽  
Author(s):  
Paul K. Y. Lam ◽  
Nigel Trendell-Smith ◽  
Jimmy H. C. Li ◽  
Y. W. Fan ◽  
Anthony P. W. Yuen
Keyword(s):  
Head And Neck ◽  
Malignant Fibrous Histiocytoma ◽  
Sphenoid Sinus ◽  
Fibrous Histiocytoma ◽  
Neck Region ◽  
Accurate Diagnosis ◽  
Close Collaboration ◽  
Rare Tumour ◽  
Head And Neck Region ◽  
Sphenoid Sinuses

Myxofibrosarcoma was originally described as the myxoid variant of malignant fibrous histiocytoma (MFH). It is uncommon in the head and neck region. We hereby report a case of myxofibrosarcoma in the sphenoid sinuses. The diagnostic and management difficulties are discussed. Close collaboration between surgeon, radiologist, histopathologist and clinical oncologist in making accurate diagnosis and appropriate management of this rare tumour are emphasized.

scholarly journals Aggressive Embryonal Orbital Rhabdomyosarcoma in an Adolescent

2021 ◽  
Vol 10 (22) ◽  
pp. 1732-1734
Author(s):  
Jacqueline Yih Ling Ting ◽  
Norlaila Talib ◽  
Mushawiahti Mustapha
Keyword(s):  
Soft Tissue ◽  
Young Children ◽  
Head And Neck ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
Soft Tissue Neoplasms ◽  
Rare Occurrence ◽  
Head And Neck Region ◽  
Mesenchymal Tissue

Rhabdomyosarcoma is a highly malignant neoplasm originating mainly from undifferentiated mesenchymal tissue. It is one of the commonest soft tissue neoplasms in the head and neck region, with an incidence of 4.3 cases per million.1 Approximately 10 % of the cases reported occur in the orbit. It is considered a disease of young children with strong male prevalence.2 This article presents a case of a 12- year-old girl with embryonal orbital rhabdomyosarcoma which is a rare occurrence among adolescents and its management challenges.

scholarly journals Clinicopathological study of skin tumours

2019 ◽  
Vol 7 (5) ◽  
pp. 1712
Author(s):  
Vaidik Shrivastava ◽  
Ashwini Tangde ◽  
Anil Joshi ◽  
Rajan Bindu
Keyword(s):  
Head And Neck ◽  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
The Body ◽  
Common Site ◽  
Skin Tumours ◽  
Head And Neck Region ◽  
Skin Cancers ◽  
Wide Range

Background: Skin cancers are relatively uncommon malignancies worldwide, but the incidence of skin cancers has progressively increased over the last few decades. The distinction between benign and malignant neoplasm are more difficult to define when they appear in skin than when found elsewhere and histopathological examination is frequently required to establish a definitive diagnosis. Diagnosis of any skin tumours can be done by correlating clinical features and histological features. The aim and objective were to study age-sex wise distribution, clinical presentation and histopathological spectrum of various skin tumours.Methods: This is a retrospective study of three years conducted in the Department of Pathology, Government Medical College, Aurangabad, India from December 2015 to December 2018. Specimens received from Department of Dermatology were fixed in formalin and after adequately processing the sections were stained routinely with H and E stain and properly evaluated for histopathological examination. This study includes tumors of epidermis along with melanogenic tumors and skin appendageal tumors. The data collected was tabulated, analysed and compared to other similar studies.Results: The study consists of 130 cases. The ratio of male to female was 1.24:1. Head and neck region (48.46%) was the most common site observed where skin lesions were present followed by extremities (37.69%). Most of the malignant tumours were presented with non-healing ulcers (30.76%) and Noduloulcerative lesions (20.33%). Out of 130 cases, 83 (63.84%) were benign whereas 47 (36.15%) were malignant tumour. According to WHO classification, keratinocytic tumour 55 (42.30%) was the most common tumour type in the present study. Skin adnexal tumours and melanocytic tumours were observed in 54 (41.53%) and 21 (16.15%) respectively.Conclusions: The skin is a complex organ. Because of complexity of skin, a wide range of diseases can develop from the skin. The majority of benign neoplasms are from skin adnexal group whereas most common malignant neoplasm were from keratinocytic group. Skin adnexal tumors can occur anywhere in the body, however head and neck region constitute the most common site. Skin adnexal tumours are clinically often misdiagnosed, so histopathological examination remains gold standard for their correct diagnosis and for their differentiation between benign and malignant neoplasm.

scholarly journals Intraoral Soft Tissue Fibrosarcoma: A Case Report and Review

2014 ◽  
Vol 4 (2) ◽  
pp. 118-123
Author(s):  
Jagdish Vishnu Tupkari ◽  
Tabita Joy Chettiakandy ◽  
Dimple Padawe ◽  
Keshav Kumar ◽  
Manisha Sardar ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Head And Neck ◽  
Soft Tissues ◽  
Malignant Neoplasm ◽  
Neck Region ◽  
Soft Tissue Tumors ◽  
The Body ◽  
World Health ◽  
Head And Neck Region

ABSTRACT Adult fibrosarcoma (FS), defined by the World Health Organization as ‘malignant neoplasm composed of fibroblasts with variable collagen production and, in classical cases, a ‘herringbone’ architecture’, is a very rare soft tissue sarcoma. The earlier literature revealed that the adult fibrosarcoma was the most commonly occurring lesion, however the incidence of which has declined dramatically over the past several decades. This is due to evolution in the classification of soft tissue tumors, recognition of its subtypes and increased understanding of the many other mesenchymal and nonmesenchymal tumors. Sarcomas are the rare group of malignancies which accounts for less than 1% of all the body sarcomas of which 5 to 15% occurs in head and neck region. It involves deep soft tissues of extremities, trunk, head and neck. Among the head and neck region, intraoral adult fibrosarcomas are very rare without any sex predilection. A case of primary soft tissue FS in posterior mandible of an 13-year-old female patient is documented here, which will be an addition to the cases reported earlier in the literatures. How to cite this article Tupkari JV, Chettiakandy TJ, Padawe D, kumar k, Sardar M, Gupta N. Intraoral Soft Tissue Fibrosarcoma: A Case Report and Review. J Contemp Dent 2014;4(2):118-123.

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