Mucosal wound and cicatricial stricture formation in the dog trachea: an experimental study

1991 ◽  
Vol 105 (3) ◽  
pp. 207-209 ◽  
Author(s):  
Wang Zhi ◽  
Chi Rucheng ◽  
Chen Wenxuan ◽  
Liu Wenzhong

AbstractComplete healing of full-thickness tracheal mucosal wounds of different sizes was studied in three groups of dogs. No stricture was observed when the mucosal wounds were less than 20×15 mm. Obvious stricture, however, occurred when the wounds were 20×25 mm. Normal epithelium regenerated on the wounded areas in all of the three groups within seven weeks.

Author(s):  
Daniel Mathies ◽  
Tsuneo Oyama ◽  
Ingo Steinbrück ◽  
Franz Ludwig Dumoulin

Abstract Background Endoscopic resection is the treatment of choice for early esophageal cancers. However, resections comprising more than 70–80 % of the circumference are associated with a high risk of stricture formation. Currently, repetitive local injections and/or systemic steroids are given for prevention. Case report We present here the case of a 78-year-old male patient who had a near circumferential endoscopic submucosal dissection for a pT1a mm, L0, V0, R0, G2 esophageal squamous cell cancer. At the end of endoscopic resection, 80 mg of triamcinolone was injected locally. The patient was then treated with oro-dispersible budesonide tablets (2 × 1 mg/day) and nystatin (4 × 100 000 I.E.) for 8 weeks. This treatment resulted in complete healing without any stricture formation and did not result in any complications. Discussion Treatment with orodispersible budesonide tablets could help prevent strictures after large endoscopic resections in the esophagus.


2015 ◽  
Vol 7 (3) ◽  
pp. 117-120 ◽  
Author(s):  
Deepak Verma ◽  
Himani Lade ◽  
Noor Ul Din Malik

ABSTRACT Objectives To evaluate the anatomical (an intact tympanic membrane without atelectasis or lateralization) and audiological outcomes of type 1 cartilage palisade tympanoplasty. Methods The prospective study was done at a tertiary referral institute included 30 patients with mucosal type chronic otitis media requiring type 1 tympanoplasty including subtotal or total perforations and revision cases. The tympanic membrane reconstruction was done using full thickness broad cartilage palisades harvested from the tragus or concha with attached perichondrium laterally. Patients were assessed at 1st, 3rd and 6th postoperative months for assessment of graft uptake, healing of tympanic membrane and hearing evaluation using pure tone audiometry. Results Total 27 out of 30 patients had fully epithelized completely healed grafts postoperatively at 1 month (success rate of 90%) while three patients had small defect. One out of these three patients showed complete healing of graft while remaining two had persistent defect at 3rd and 6th months postoperatively. The mean pure tone air bone gap considerably reduced from 33.27 ± 4.29 dB preoperatively to 12.67 ± 5.68 dB postoperatively at 6 months. Conclusion Tympanic membrane reconstruction using full thickness palisades of cartilage provides good anatomical and audiological results with significant improvement of hearing specially in cases of subtotal or total perforations, revision surgery, atelectasis and Eustachian tube disorders where healing of tympanic membrane has much poorer prognosis irrespective of the surgical technique used. How to cite this article Gupta S, Lade H, Verma D, Malik NUD. Cartilage Palisade Type 1 Tympanoplasty: Anatomical and Audiological Outcomes. Int J Otorhinolaryngol Clin 2015;7(3):117-120.


2011 ◽  
Vol 28 (2) ◽  
pp. 171-177 ◽  
Author(s):  
Sophie Böttcher-Haberzeth ◽  
Thomas Biedermann ◽  
Clemens Schiestl ◽  
Fabienne Hartmann-Fritsch ◽  
Jörg Schneider ◽  
...  

Biomaterials ◽  
1992 ◽  
Vol 13 (9) ◽  
pp. 625-634 ◽  
Author(s):  
J. Klompmaker ◽  
H.W.B. Jansen ◽  
R.P.H. Veth ◽  
H.K.L. Nielsen ◽  
J.H. de Groot ◽  
...  

2014 ◽  
Vol 79 (5) ◽  
pp. AB473
Author(s):  
Kiyoshi Hashiba ◽  
Horus a. Brasil ◽  
Jorge C. Cassab ◽  
Fernando Marson ◽  
Pablo R. Siqueira ◽  
...  

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