The effect of uvulopalatopharyngoplasty without tonsillectomy using local anaesthesia: a prospective long-term follow-up

AbstractThis paper presents the long-term effect of restricted surgery for snoring and sleep apnoea. Patients with obstructive sleep apnoea (OSAS) (19) or heavy snoring (HS) (36) were studied prospectively for five to seven years after uvulopalatopharyngoplasty without tonsillectomy performed by regular surgical technique using local anaesthesia (LUPP). Five years after surgery, 90 per cent answered a questionnaire. All OSAS patients were offered a polysomnography, and the HS patients were offered a sleep study. Eighty per cent still showed a positive effect on daytime somnolence, and 77 per cent on snoring. Sideeffects were reported by 40 per cent; most common was choking (20 per cent) the first year. Eighteen per cent had local problems such as globus sensation. The polysomnography showed that 80 per cent were still ‘responders’ with an apnoea index (AI) reduction of >50 per cent. None of the HS patients had developed OSAS. In conclusion, LUPP in selected patients with OSAS or HS has a good long-term effect. Sideeffects are common, but diminish with time.

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Comparison between short-term and long-term post-operative evaluation of sleep apnoea after uvulopalatopharyngoplasty

The Journal of Laryngology & Otology ◽

10.1017/s0022215100129998 ◽

1995 ◽

Vol 109 (4) ◽

pp. 308-312 ◽

Cited By ~ 29

Author(s):

Shao-Jung Lu ◽

Shyue-Yih Chang ◽

Guang-Ming Shiao

Keyword(s):

Sleep Apnoea ◽

Obstructive Sleep Apnoea Syndrome ◽

Sleep Study ◽

Obstructive Sleep ◽

Study Results ◽

Significant Difference ◽

Long Term Follow Up ◽

Operative Evaluation

AbstractFor a long time uvulopalatopharyngoplasty (UPPP) has been used to treat the obstructive sleep apnoea syndrome (OSAS). The diverse surgical effects, the inadequate understanding of operation effect consistency, the possibility of disease progression, and the few reported papers for long-term evaluation after UPPP aroused our interest in designing this study. Fifteen OSAS patients who had undergone UPPP with pre-operative, initial post-operative and long-term post-operative polysomnographic studies were included in this study. Long-term post-operative polysomnography was undertaken more than five years after surgery. The polysomnographic evaluations included respiratory disturbance index (RD I), duration of saturation SaO2 <85 per cent (DOS), and the lowest O2 saturation (LOS). Amongst them, 10 patients with initial post-operative RDI reduction > 50 per cent were considered responders. In these responders, the long-term follow-up results of all three parameters showed improvement compared to the preoperative data. In a comparison between the initial and long-term post-operative sleep study results, LOS and DOS showed no significant difference. However, the long-term post-operative RDI result became significantly worse. More than 80 per cent of all cases had subjective symptomatic improvement in the long-term post-operative evaluation. The subjective improvement after operation is not adequately correlated to the polysomnographic result. We suggest that long-term follow-up for patients after UPPP is necessary.

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Long Term Effect of Autoadjusting Positive Airway Pressure on C-Reactive Protein and Interleukin-6 in Men With Obstructive Sleep Apnoea Syndrome

Archivos de Bronconeumología (English Edition) ◽

10.1016/s1579-2129(09)73447-0 ◽

2009 ◽

Vol 45 (12) ◽

pp. 577-584 ◽

Cited By ~ 2

Author(s):

Marta Drummond ◽

João Winck ◽

João Guimarães ◽

Ana C. Santos ◽

João Almeida ◽

...

Keyword(s):

Positive Airway Pressure ◽

Sleep Apnoea ◽

Term Effect ◽

Obstructive Sleep Apnoea Syndrome ◽

C Reactive Protein ◽

Reactive Protein ◽

Long Term Effect ◽

Obstructive Sleep ◽

Autoadjusting Positive Airway Pressure

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Faculty Opinions recommendation of Long-term effect of weight loss on obstructive sleep apnea severity in obese patients with type 2 diabetes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718006218.793506796 ◽

2015 ◽

Author(s):

Martica Hall

Keyword(s):

Type 2 Diabetes ◽

Weight Loss ◽

Obstructive Sleep Apnea ◽

Term Effect ◽

Obese Patients ◽

Long Term Effect ◽

Obstructive Sleep Apnea Severity ◽

Obstructive Sleep

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Nutritional deficiencies and later behavioural development

Proceedings of The Nutrition Society ◽

10.1017/s0029665100000069 ◽

2000 ◽

Vol 59 (1) ◽

pp. 47-54 ◽

Cited By ~ 54

Author(s):

S. M. Grantham-McGregor ◽

S. P. Walker ◽

S. Chang

Keyword(s):

Cultural Context ◽

School Achievement ◽

Protein Energy Malnutrition ◽

Term Effect ◽

Nutritional Deficiencies ◽

Long Term Effects ◽

Protein Energy ◽

Long Term Effect ◽

Long Term Follow Up

The literature on the long-term effects of nutritional deficiencies in early life is reviewed. The severity and duration of the deficiency, the stage of the children’s development, the biological condition of the children and the socio-cultural context may all modify the effect. There is substantial evidence that reduced breast-feeding, small-for-gestational-age birth weight, Fe and I deficiency, and protein-energy malnutrition (PEM) are associated with long-term deficits in cognition and school achievement. However, all these conditions are associated with poverty and poor health, which may account for the association. It is difficult to establish that the long-term relationship is causal, as it requires a randomized treatment trial with long-term follow-up. Such studies are only available for I deficiency in utero and early childhood PEM. Results from these studies indicate that I deficiency has a long-term effect and PEM probably has a long-term effect.

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