Congenital granular cell epulis: report of a case and review of the literature

Congenital granular cell tumour of the new born is a rare benign lesion of soft tissues which normally affects the maxillary alveolar ridge in neonates. Though benign, it can cause respiratory embarrassment and prevent feeding causing physical distress to the infant and psychological distress to the parents or guardian. Very few cases are reported in the literature. We aimed to highlight the clinical presentation, management and a brief review of the literature of the lesion.A case of a 3-day old baby who presented to the Oral and Maxillofacial Surgery Clinic University of Benin Teaching Hospital (UBTH) was used to illustrate the clinical presentation and management of congenital epulis.Congenital epulis of the new-born is a rare occurrence, though it can grow to a frightening size, it still remains a benign lesion with li le or no recurrence following surgical excision. The role of counselling to the parents cannot be over-emphasized.Keywords: Congenital, epulis, granular, newborn

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Surgical Excision of Orbital Progressive Granular Cell Tumour

Case Reports in Ophthalmological Medicine ◽

10.1155/2015/420490 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Demetrio Germanò ◽

Hossein Mostafa Elbadawy ◽

Diego Ponzin ◽

Daniele Ferro ◽

Leonardo Priore

Keyword(s):

Ct Scan ◽

Benign Lesion ◽

Granular Cell ◽

Surgical Excision ◽

Cell Tumour ◽

Granular Cell Tumour ◽

Initial Examination ◽

Orbital Mass ◽

S 100 ◽

Substantial Progress

Granular cell tumour (GCT) is mostly benign lesion first described by Abrikossoff and named after him. Most cases are reported in the head and neck area, where the tongue is the most common site. Here we review previous cases in the literature for GCT in the orbit and present a new case. A 49-year-old male presented with apparent exophthalmos. Examination of the patient revealed the presence of a mass in the bottom side of the orbit. A substantial progress was noted after two months from the initial examination using computed tomography (CT) scan. An orbital mass was extracted and histological analysis showed signs typical for GCT. Immunohistochemistry was positive for S-100; the biopsy showed no mitotic or necrotic areas. Proptosis was resolved after surgery and a six-year follow-up CT scan was performed. We conclude that rapid progress of the tumour does not necessarily suggest malignancy.

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Epiglottic granular cell tumour: a case report and literature review

Journal of Surgical Case Reports ◽

10.1093/jscr/rjaa009 ◽

2020 ◽

Vol 2020 (2) ◽

Author(s):

Sarah Bouayyad ◽

Jen Ong ◽

Houda Bouayyad ◽

Heerani Woodun

Keyword(s):

Soft Tissues ◽

Anterior Commissure ◽

Incidental Finding ◽

Granular Cell ◽

Surgical Excision ◽

Cell Tumour ◽

General Anaesthetic ◽

Granular Cell Tumour ◽

Rare Tumour ◽

Rare Benign Tumour

Abstract Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.

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CONGENITAL GRANULAR CELL TUMOUR : A RARE CASE REPOR

10.36106/gjra/1001516 ◽

2020 ◽

pp. 1-2

Author(s):

Sabari Devi ◽

Waziha Ahmed

Keyword(s):

Smooth Muscle ◽

Smooth Muscle Cells ◽

Recurrence Rate ◽

Rare Case ◽

Benign Lesion ◽

Granular Cell ◽

Surgical Excision ◽

Cell Tumour ◽

Granular Cell Tumour ◽

Feeding Problems

Congenital granular cell tumour/ epulis (CGCE) is a rare benign lesion of the newborn. It was first described in 1871 by Neumann. It usually arises from the alveolar mucosa of neonates and may cause respiratory and feeding problems. The exact histogenesis is unclear. The proposed source of origin includes undifferentiated mesenchymal cells, odontogenic epithelial, pericytes, fibroblasts, smooth muscle cells. Treatment involves surgical excision and and its curative with rare recurrence rate.

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Unusual presentation of granular cell tumour of buccal mucosa

BMJ Case Reports ◽

10.1136/bcr-2021-242242 ◽

2021 ◽

Vol 14 (9) ◽

pp. e242242

Author(s):

Zhi Yon Charles Toh ◽

Thomas Cooper ◽

Maryam Jessri ◽

Frank S-C Chang

Keyword(s):

Buccal Mucosa ◽

Correct Diagnosis ◽

Granular Cell ◽

Surgical Excision ◽

Cell Tumour ◽

Granular Cell Tumour ◽

Complete Surgical Excision ◽

Uncommon Presentation ◽

Long Term Follow Up

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.

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Oral granular cell tumors: an analysis of 10 new pediatric and adolescent cases and a review of the literature

Journal of Clinical Pediatric Dentistry ◽

10.17796/jcpd.29.1.h310lq3363522441 ◽

2005 ◽

Vol 29 (1) ◽

pp. 69-74 ◽

Cited By ~ 26

Author(s):

Robert Brannon ◽

Payal Anand

Keyword(s):

English Language ◽

Granular Cell Tumor ◽

Granular Cell ◽

Surgical Excision ◽

Cell Tumor ◽

Review Of The Literature ◽

Soft Tissue Neoplasm ◽

Adolescent Population ◽

Male Ratio ◽

Common Location

Clinicopathologic studies on the granular cell tumor, a submucosal benign soft-tissue neoplasm, have not addressed the pediatric and adolescent population. This study of patients from birth to 19 years of age describes clinically and microscopically 10 new cases and combines them with 24 well-documented pediatric cases previously published in the English-language literature. Of the 34, patient ages ranged from 3 to 19 years (mean age 14.5 years) with a female-to-male ratio of 3.3 to 1. The most common location was the tongue (50%) and lips (25%). In neoplasms whose epithelial findings were documented microscopically, a reactive pseudoepitheliomatous (pseudocarcinomatous) hyperplasia of the overlying epithelium occurred in 29%. The recurrence rate was less than 10% following conservative surgical excision. This study reveals that an oral granular cell tumor in the first decade of life is an uncommon event and discusses the importance of differentiating between squamous cell carcinoma and granular cell tumor.

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A Rare Presentation of Inflammatory Myofibroblastic Tumor in the Nasolabial Fold

Case Reports in Otolaryngology ◽

10.1155/2019/3257697 ◽

2019 ◽

Vol 2019 ◽

pp. 1-5

Author(s):

Hind K. Alshammari ◽

Haya F. Alzamami ◽

Mona Ashoor ◽

Wasan F. Almarzouq ◽

Haitham Kussaibi

Keyword(s):

Inflammatory Myofibroblastic Tumor ◽

Soft Tissues ◽

Histopathological Examination ◽

Benign Lesion ◽

Neck Region ◽

Surgical Excision ◽

Nasolabial Fold ◽

Rare Presentation ◽

The Central Nervous System ◽

Sublabial Approach

Inflammatory myofibroblastic tumor (IMT) is a benign lesion that occurs most frequently in the soft tissues and viscera. In the head and neck region, the tumor has been reported to occur in the orbit, tongue, nasopharynx, larynx, and paranasal sinuses and the central nervous system. Despite being a benign lesion, it exhibits infiltrative and destructive behaviours, making histopathological examination necessary to confirm the diagnosis. We report the case of a 38-year-old female presented with a right nasolabial fold mass, which was confirmed histologically to be an IMT. Surgical excision of the mass was achieved through a sublabial approach with an uneventful postoperative period. To the best of our knowledge, this is the first reported case of an IMT in the nasolabial fold.

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Use of Platelet-Rich Plasma and Platelet-Rich Fibrin in Dentistry and Oral Surgery: Introduction and Review of the Literature

Journal of Veterinary Dentistry ◽

10.1177/0898756419876057 ◽

2019 ◽

Vol 36 (2) ◽

pp. 109-123 ◽

Cited By ~ 5

Author(s):

Kristina Feigin ◽

Bonnie Shope

Keyword(s):

Soft Tissues ◽

Oral Surgery ◽

Platelet Rich Plasma ◽

Maxillofacial Surgery ◽

Oral And Maxillofacial Surgery ◽

Platelet Concentrates ◽

Platelet Rich Fibrin ◽

Wide Range ◽

Comprehensive Examination ◽

And Function

Platelet concentrates, mostly represented by platelet-rich plasma and platelet-rich fibrin, have gained significant interest in various medical and oral disciplines because of their potential to stimulate and boost regeneration of hard and soft tissues. Prepared from the patient’s own blood, they have been tested and used in various different surgical fields including oral and maxillofacial surgery. The effects of these biomaterials are described to be a result of the large concentration of platelets which contain a wide range of growth factors. The aim of this article is to introduce the principle and function of these platelet concentrates, to review their preparation, and to provide a comprehensive examination of the published oral and maxillofacial literature on this subject.

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