The growth hormone response to insulin induced hypoglycaemia in alcoholics

synopsisThe growth hormone response to insulin induced hypoglycaemia was studied in 7 alcoholic in-patients who had been abstinent for 2–11 days and in 10 normal controls. Blood samples were taken at intervals after the injection of soluble insulin (0·1 U/kg body weight). The growth hormone response was impaired in 4 of the alcoholics and the depression was not related to differences in blood glucose or plasma free fatty acids. The Cortisol response was also impaired in the alcoholics. We conclude that alcoholics observed after alcohol withdrawal may have a depression of hypothalamic/pituitary function.

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Faculty Opinions recommendation of Effects of gender, body weight, and blood glucose dynamics on the growth hormone response to the glucagon stimulation test in patients with pituitary disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726089624.793538651 ◽

2017 ◽

Author(s):

Cesar Boguszewski

Keyword(s):

Growth Hormone ◽

Body Weight ◽

Blood Glucose ◽

Growth Hormone Response ◽

Stimulation Test ◽

Hormone Response ◽

Glucagon Stimulation Test ◽

Pituitary Disease ◽

Glucose Dynamics

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Effects of gender, body weight, and blood glucose dynamics on the growth hormone response to the glucagon stimulation test in patients with pituitary disease

Growth Hormone & IGF Research ◽

10.1016/j.ghir.2015.12.005 ◽

2016 ◽

Vol 26 ◽

pp. 24-31 ◽

Cited By ~ 5

Author(s):

Jessica R. Wilson ◽

Andrea L. Utz ◽

Jessica K. Devin

Keyword(s):

Growth Hormone ◽

Body Weight ◽

Blood Glucose ◽

Growth Hormone Response ◽

Stimulation Test ◽

Hormone Response ◽

Glucagon Stimulation Test ◽

Pituitary Disease ◽

Glucose Dynamics

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Growth hormone response to TRH in male broiler chickens selected for body weight gain or food conversion and reared at either a moderate or a high ambient temperature

Reproduction Nutrition Development ◽

10.1051/rnd:19920206 ◽

1992 ◽

Vol 32 (2) ◽

pp. 135-141 ◽

Cited By ~ 2

Author(s):

M. Herremans ◽

J. Buyse ◽

FR Leenstra ◽

G. Beuving ◽

L. Berghman ◽

...

Keyword(s):

Growth Hormone ◽

Body Weight ◽

Weight Gain ◽

Ambient Temperature ◽

Broiler Chickens ◽

Body Weight Gain ◽

High Ambient Temperature ◽

Growth Hormone Response ◽

Hormone Response ◽

Food Conversion

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Growth hormone response to clonidine and the cortisol response to dexamethasone in depressive patients

Psychiatry Research ◽

10.1016/0165-1781(95)02606-1 ◽

1996 ◽

Vol 60 (1) ◽

pp. 23-32 ◽

Cited By ~ 20

Author(s):

Sergio Valdivieso ◽

Fabrice Duval ◽

Marie-Claude Mokrani ◽

Nicolas Schaltenbrand ◽

Juarez Oliveira Castro ◽

...

Keyword(s):

Growth Hormone ◽

Growth Hormone Response ◽

Cortisol Response ◽

Hormone Response ◽

Depressive Patients

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Growth hormone response to apomorphine in panic disorder: Comparison with major depression and normal controls

European Archives of Psychiatry and Clinical Neuroscience ◽

10.1007/bf02191872 ◽

1995 ◽

Vol 245 (6) ◽

pp. 306-308 ◽

Cited By ~ 10

Author(s):

William Pitchot ◽

Michel Hansenne ◽

Antonio Gonzalez Moreno ◽

Marc Ansseau

Keyword(s):

Growth Hormone ◽

Major Depression ◽

Panic Disorder ◽

Growth Hormone Response ◽

Hormone Response ◽

Normal Controls

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Blood Glucose, Serum Insulin and Growth Hormone Response to Intravenous Administration of Arginine in Premature Infants

Neonatology ◽

10.1159/000240470 ◽

1972 ◽

Vol 20 (3-4) ◽

pp. 262-269 ◽

Cited By ~ 11

Author(s):

C. Ponté ◽

B. Gaudier ◽

B. Deconinck ◽

J.C. Fourlinnie

Keyword(s):

Growth Hormone ◽

Blood Glucose ◽

Premature Infants ◽

Intravenous Administration ◽

Serum Insulin ◽

Growth Hormone Response ◽

Hormone Response

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CHANGES IN BLOOD GLUCOSE AND PLASMA INSULIN, FREE FATTY ACIDS, GROWTH HORMONE AND 11-HYDROXYCORTICOSTEROIDS DURING INTRAMUSCULAR VASOPRESSIN TESTS IN CHILDREN AND ADOLESCENTS

Acta Endocrinologica ◽

10.1530/acta.0.0580545 ◽

1968 ◽

Vol 58 (4) ◽

pp. 545-557 ◽

Cited By ~ 6

Author(s):

M. Karp ◽

A. Pertzelan ◽

M. Doron ◽

A. Kowadlo-Silbergeld ◽

Z. Laron

Keyword(s):

Fatty Acids ◽

Growth Hormone ◽

Blood Glucose ◽

Free Fatty Acids ◽

Growth Hormone Deficiency ◽

Plasma Insulin ◽

Hormone Deficiency ◽

Pituitary Insufficiency ◽

Isolated Growth Hormone Deficiency ◽

Normal Controls

ABSTRACT Lysine-8-vasopressin (LVP) was administered intramuscularly in a dose of 5–10 units to 20 children and adolescents, divided into the following 3 groups: I – normal controls; II – patients with isolated growth hormone deficiency; III – patients with pituitary insufficiency involving several hormones. In all the patients studied, LVP induced a rise in plasma 11-hydroxycorticosteroids. In the normal controls LVP induced a moderate rise in blood glucose. Patients with isolated growth hormone deficiency showed no rise, and those with pituitary insufficiency involving several hormones showed a great variability in response. In all 3 groups there was a sharp decrease in plasma free fatty acids, most marked in the patients with isolated growth hormone deficiency, and a slower return to base line levels. There was no change in the plasma concentration of growth hormone in any of the patients. Plasma insulin rose moderately in the normal controls; there was little or no change in any of the patients with pituitary insufficiency. The above finding that LVP induced a reduction in plasma free fatty acids in the patients with pituitary insufficiency without any concomitant elevation of plasma insulin and blood glucose, is in agreement with the assumption that LVP acts directly on adipose tissue.

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