Faculty Opinions recommendation of Effects of gender, body weight, and blood glucose dynamics on the growth hormone response to the glucagon stimulation test in patients with pituitary disease.

Author(s):  
Cesar Boguszewski
1977 ◽  
Vol 7 (4) ◽  
pp. 607-611 ◽  
Author(s):  
R. J. Chalmers ◽  
E. H. Bennie ◽  
R. H. Johnson ◽  
H. G. Kinnell

synopsisThe growth hormone response to insulin induced hypoglycaemia was studied in 7 alcoholic in-patients who had been abstinent for 2–11 days and in 10 normal controls. Blood samples were taken at intervals after the injection of soluble insulin (0·1 U/kg body weight). The growth hormone response was impaired in 4 of the alcoholics and the depression was not related to differences in blood glucose or plasma free fatty acids. The Cortisol response was also impaired in the alcoholics. We conclude that alcoholics observed after alcohol withdrawal may have a depression of hypothalamic/pituitary function.


1994 ◽  
Vol 83 (1) ◽  
pp. 103-105 ◽  
Author(s):  
J Pineda ◽  
C Dieguez ◽  
FF Casanueva ◽  
P Martul

Author(s):  
Andrew Ellis ◽  
John Seth ◽  
Ruth Al-Sadie ◽  
Julian H Barth

Introduction: Measurement of serum growth hormone (GH) concentration in response to insulin-induced hypoglycaemia remains an important investigation in the assessment of pituitary disease. Methods In this audit, laboratories were presented with aliquots of sera with GH concentrations likely to be found in an insulin stress test (IST). They were invited to analyse the specimens for GH and comment on their results. Results and discussion: A number of laboratories appeared to be using out-of-consensus cut-off concentrations that sometimes were unrelated to the bias of their GH assay. The specimens were chosen to mimic those seen in an IST that was clearly not indicative of GH deficiency, so there was reasonable consensus in the interpretation of results. However, five laboratories (9·6%) did indicate that their results were equivocal.


2021 ◽  
Vol 73 (5) ◽  
Author(s):  
Sara PAGANI ◽  
Gianpaolo DE FILIPPO ◽  
Giulia GENONI ◽  
Domenico RENDINA ◽  
Cristina MEAZZA ◽  
...  

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