scholarly journals Time trends in depression prevalence among Swedish 85-year-olds: repeated cross-sectional population-based studies in 1986, 2008, and 2015

2021 ◽  
pp. 1-10
Author(s):  
Mattias Jonson ◽  
Robert Sigström ◽  
Khedidja Hedna ◽  
Therese Rydberg Sterner ◽  
Hanna Falk Erhag ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drug Use ◽  
Psychotropic Drug ◽  
Time Trends ◽  
Rating Scale ◽  
Related Factors ◽  
Cross Sectional ◽  
Psychotropic Drug Use ◽  
Prevalence Of Depression ◽  
Health Related

Abstract Background Octogenarians of today are better educated, and physically and cognitively healthier, than earlier born cohorts. Less is known about time trends in mental health in this age group. We aimed to study time trends in the prevalence of depression and psychotropic drug use among Swedish 85-year-olds. Methods We derived data from interviews with 85-year-olds in 1986–1987 (N = 348), 2008–2010 (N = 433) and 2015–17 (N = 321). Depression diagnoses were made according to the Diagnostic and Statistical Manual of Mental Disorders. Symptom burden was assessed with the Montgomery-Åsberg Depression Rating Scale (MADRS). Information on psychotropic drug use, sociodemographic, and health-related factors were collected during the interviews. Results The prevalence of major depression was lower in 2015–2017 (4.7%, p < 0.001) and 2008–2010 (6.9%, p = 0.010) compared to 1986–1987 (12.4%). The prevalence of minor depression was lower in 2015–2017 (8.1%) compared to 2008–2010 (16.2%, p = 0.001) and 1986–1987 (17.8%, p < 0.001). Mean MADRS score decreased from 8.0 in 1986–1987 to 6.5 in 2008–2010, and 5.1 in 2015–2017 (p < 0.001). The reduced prevalence of depression was not explained by changes in sociodemographic and health-related risk factors for depression. While psychoactive drug use was observed in a third of the participants in each cohort, drug type changed over time (increased use of antidepressants and decreased use of anxiolytics and antipsychotics). Conclusions The prevalence of depression in octogenarians has declined during the past decades. The decline was not explained by changes in known risk factors for depression. The present study cannot answer whether changed prescription patterns of psychoactive drugs have contributed to the decline.

scholarly journals A cross-sectional study of psychotropic drug use in the elderly: Consuming patterns, risk factors and potentially inappropriate use

2019 ◽  
pp. ejhpharm-2019-001927
Author(s):  
María Isabel Santos-Pérez ◽  
Inmaculada Fierro ◽  
M Esther Salgueiro-Vázquez ◽  
María Sáinz-Gil ◽  
Luis H Martín-Arias
Keyword(s):  
Risk Factors ◽  
Drug Use ◽  
Psychotropic Drug ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Inappropriate Use ◽  
Psychotropic Drug Use

Psychotropic Drug Use Among the Elderly: Risk Factors Involved in Long-Term Use

2010 ◽  
Vol 45 (7-8) ◽  
pp. 1050-1059 ◽  
Author(s):  
Valérie Aubron ◽  
Vincent Camus ◽  
Badiâa Bouazzaoui ◽  
Antoine Pélissolo ◽  
Grégory Michel
Keyword(s):  
Risk Factors ◽  
Drug Use ◽  
Psychotropic Drug ◽  
The Elderly ◽  
Psychotropic Drug Use

scholarly journals Change in psychotropic drug use among community-dwelling people aged 75 years and older in Finland: repeated cross-sectional population studies

2011 ◽  
Vol 23 (8) ◽  
pp. 1278-1284 ◽  
Author(s):  
Franciska Desplenter ◽  
Charlotte Caenen ◽  
Jolein Meelberghs ◽  
Sirpa Hartikainen ◽  
Raimo Sulkava ◽  
...  
Keyword(s):  
Drug Use ◽  
Psychotropic Drug ◽  
Adverse Drug Events ◽  
Community Dwelling ◽  
Cross Sectional ◽  
Psychotropic Drug Use ◽  
Random Samples ◽  
Antidepressant Use ◽  
Status Differences ◽  
Compare And Contrast

ABSTRACTBackground: Older people are at high risk of experiencing psychotropic-related adverse drug events. The objective of this study was to compare and contrast the use of psychotropic drugs among community-dwelling people aged ≥75 years in 1998 and 2004.Methods: Comparable random samples of people aged ≥75 years were extracted from the population register in Kuopio, Finland, in 1998 (n = 700) and 2003 (n = 1000). In 1998 and 2004, 523 and 700 community-dwelling people respectively participated in nurse interviews, during which demographic, diagnostic and drug use data were elicited. Logistic regression was used to compute unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the prevalence of psychotropic drug use in 2004 compared to 1998.Results: The unadjusted prevalence of total psychotropic (37.3% and 38.4%, OR 1.05; 95% CI 0.83–1.33), anxiolytic, hypnotic and sedative (29.6% and 31.3%, OR 1.08, 95% CI 0.85–1.38), and antidepressant (10.7% and 11.9%, OR 1.12, 95% CI 0.78–1.61) use were similar in 1998 and 2004. There was a decrease in the unadjusted prevalence of antipsychotic use (9.2% and 5.7%, OR 0.60; 95% CI 0.39–0.93). After adjusting for socioeconomic and health status differences, there was an increase in the prevalence of total psychotropic (adjusted OR 1.31, 95% CI 1.01–1.70) and antidepressant (OR 1.59, 95% CI 1.06–2.40) use.Conclusion: The unadjusted prevalence of psychotropic drug use remained stable between 1998 and 2004. However, in adjusted analyses there was a small increase in the prevalence of any psychotropic drug use and antidepressant use specifically.

Self-reported psychotropic drug use and associated factors in a French community sample

1992 ◽  
Vol 22 (1) ◽  
pp. 181-190 ◽  
Author(s):  
P. Pariente ◽  
J. P. Lépine ◽  
J. Lellouch
Keyword(s):  
Drug Use ◽  
Psychotropic Drug ◽  
Community Sample ◽  
Age Groups ◽  
Household Survey ◽  
Well Being ◽  
Cross Sectional ◽  
Logistic Analysis ◽  
Psychotropic Drug Use ◽  
History Of

SYNOPSISDrug use was examined in a French general population adult sample from a household survey conducted in 1987–8 in a newly built town near Paris. Psychotropic drug use was measured by the percentage of subjects reporting their use during the past week. It was prominently represented by benzodiazepines (90% of psychotropic users), differed strongly between genders (4·6% in men, 10·2% in women) and age groups (higher after 40 years). A lifetime history of major depressive episode (MDE) or of anxiety disorders was associated with a higher proportion of psychotropic drug use. Psychotropic drug use also went with a current well-being questionnaire score. Using a logistic analysis, the following set of variables held for women: well-being score, history of both MDE and anxiety disorder, age, and marital status. Making allowance for the cross-sectional nature of this retrospective survey, these finding confirmed the relatively high level of benzodiazepine drug use in an urban French community sample and emphasized its association with mental health status.

scholarly journals Prevalence and Risk Factors for Depression among Caregivers of Alzheimer’s Disease Patients in Saudi Arabia

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Mohammed Saeed Alqahtani ◽  
Ahmad Ayed Alshbriqe ◽  
Ahmed A. Awwadh ◽  
Turki Ali Alyami ◽  
Mohammed Saad Alshomrani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rating Scale ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Mild Depression ◽  
Cross Sectional ◽  
Prolonged Stay ◽  
High Risk Factors ◽  
Prevalence Of Depression ◽  
Getting Lost

Objectives. To identify prevalence and risk factors of depression among caregivers of Alzheimer’ disease (AD) patients. Methods. In a cross-sectional study, 110 caregivers of AD patients participated in this study (51 males and 59 females). Patients data were obtained from patients’ records at Aseer Central Hospital. Depression among caregivers was assessed by using the Hamilton Rating Scale for Depression. Results. The age of caregivers ranged from 17 to 85 years (Mean±SD: 41.1±14.0 years). Prevalence of depression among caregivers was 70%. Caregivers were mainly sons/daughters (69.1%) or spouses (11.8%). A total of 33 caregivers (30%) had mild depression while 44 (40%) had moderate depression. Prevalence of depression was significantly higher among caregivers of AD patients who were exposed to repeated falling down (p=0.003), but did not differ significantly among caregivers who were exposed to repeated pneumonia or getting lost. Caregivers’ scores of depression positively correlated with duration of caregivers’ daily stay with AD patients (r=0.272, p=0.004), but did not correlate significantly with either caregivers’ age or patients’ age. Moreover, caregivers’ depression did not differ significantly according to their marital status, educational status, employment status, or monthly income. Conclusions. Prevalence of depression among AD caregiver is high. Risk factors for depression include patients’ exposure to repeated falls and prolonged stay with patients. Therefore, psychiatric care should be provided to caregivers, home safety should be maintained to avoid falls, and several persons should interchangeably provide care to AD patients.

Psychotropic drug use in relation to mental disorders and institutionalization among 95-year-olds: a population-based study

2011 ◽  
Vol 23 (8) ◽  
pp. 1270-1277 ◽  
Author(s):  
Eva Lesén ◽  
Anders Carlsten ◽  
Ingmar Skoog ◽  
Margda Waern ◽  
Max Petzold ◽  
...  
Keyword(s):  
Drug Use ◽  
Mental Disorders ◽  
Psychotropic Drug ◽  
Psychotropic Drugs ◽  
Psychotic Disorders ◽  
Rating Scale ◽  
The Elderly ◽  
Population Based ◽  
Prescribing Patterns ◽  
Psychotropic Drug Use

ABSTRACTBackground: The prevalence of psychotropic drug use is high among the elderly, but research on how psychotropic drugs are used among individuals aged 90 years and older is limited. An increased knowledge on this topic may contribute to improved prescribing patterns in this vulnerable population. The aim of this study was to assess the use of psychotropic drugs in relation to mental disorders and institutionalization among 95-year-olds and to identify use of potentially inappropriate psychotropic drugs.Methods: All 95-year-olds born in 1901–1903 living in nursing homes or community settings in Gothenburg, Sweden were invited to participate. The response rate was 65% and 338 95-year-olds were examined (263 women, 75 men). Psychotropic drug use in relation to mental disorders and institutionalization was assessed. Information on drug use was collected primarily from multi-dose drug dispensing lists. Participants were examined by trained psychiatrists using the Comprehensive Psychopathological Rating Scale and a battery of cognitive tests. Dementia, depression, anxiety and psychotic disorders were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, third edition, revised (DSM-III-R).Results: Sixty percent of the 95-year-old participants used psychotropic drugs; hypnotics were most common (44%). Potentially inappropriate psychotropics were observed in one third (33%). Antidepressants were used by 7% of the participants without dementia who fulfilled criteria for a depressive disorder, while 56% used hypnotics and 30% used anxiolytics.Conclusions: The high prevalence of psychotropic drug use and the nonspecific nature of these treatments among 95-year-olds indicate a need for improvement in prescribing patterns.

P2-293: TIME TRENDS IN PSYCHOTROPIC DRUG USE IN PATIENTS WITH DEMENTIA: A NATIONWIDE STUDY

2014 ◽  
Vol 10 ◽  
pp. P585-P585
Author(s):  
Ane Nørgaard ◽  
Christina Jensen-Dahm ◽  
Christiane Gasse ◽  
Aske Aastrup ◽  
Gunhild Waldemar
Keyword(s):  
Drug Use ◽  
Psychotropic Drug ◽  
Time Trends ◽  
Nationwide Study ◽  
Psychotropic Drug Use

Only 10% of the psychotropic drug use for neuropsychiatric symptoms in patients with dementia is fully appropriate. The PROPER I-study

2016 ◽  
Vol 28 (10) ◽  
pp. 1589-1595 ◽  
Author(s):  
Klaas van der Spek ◽  
Debby L. Gerritsen ◽  
Martin Smalbrugge ◽  
Marjorie H. J. M. G. Nelissen-Vrancken ◽  
Roland B. Wetzels ◽  
...  
Keyword(s):  
Nursing Home ◽  
Drug Use ◽  
Psychotropic Drug ◽  
Neuropsychiatric Symptoms ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Inappropriate Use ◽  
Psychotropic Drug Use ◽  
Nursing Home Patients ◽  
Sum Score

ABSTRACTBackground:This study explores the appropriateness of psychotropic drug (PD) use for neuropsychiatric symptoms (NPS) in nursing home patients with dementia.Methods:A cross-sectional study on 559 patients with dementia residing on dementia special care units in Dutch nursing homes was conducted. Appropriateness of PD use was assessed using the Appropriate Psychotropic drug use In Dementia (APID) index. The APID index score is calculated using information about individual PDs from patients’ medical records. The index encompasses seven (different) domains of appropriateness, i.e. indication, evaluation, dosage, drug-drug interactions, drug-disease interactions, duplications, and therapy duration.Results:A total of 578 PDs were used for NPS by 60% of the nursing home patients. Indication, evaluation, and therapy duration contributed the most to inappropriate use. Ten per cent of the PDs scored fully appropriate according to the APID index sum score, 36% scored fully appropriate for indication, 46% scored fully appropriate for evaluation, and 58% scored fully appropriate for therapy duration. Antidepressants were used the most appropriately, and antiepileptics the most inappropriately.Conclusions:The minority of the PD use was fully appropriate. The results imply that PD use for NPS in dementia can be improved; the appropriateness should be optimized with a clinical focus on the appropriate indications, evaluations, and therapy duration.

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