scholarly journals A High-Throughput, Low-Cost Method for Analysis of Carbonate Samples for 14C

Radiocarbon ◽  
2013 ◽  
Vol 55 (2) ◽  
pp. 585-592 ◽  
Author(s):  
Mark L Roberts ◽  
Steven R Beaupré ◽  
Joshua R Burton
Keyword(s):  
Mass Spectrometry ◽  
Cost Analysis ◽  
High Throughput ◽  
Accelerator Mass Spectrometry ◽  
Organic Material ◽  
Low Cost ◽  
Automated System ◽  
Woods Hole Oceanographic Institution ◽  
Ocean Sciences ◽  
Better Than

The National Ocean Sciences Accelerator Mass Spectrometry (NOSAMS) facility at the Woods Hole Oceanographic Institution has developed an automated system for high-throughput, low-cost analysis of radiocarbon in carbonate samples (e.g. corals, carbonaceous sediments, speleothems, etc.). The method bypasses graphitization and pretreatment, and reduces costs to about 1/5th the price of a graphite-based 14C carbonate analysis, with a throughput of 60 unknowns per day and an analytical precision of better than 2%. Additionally, a simple mixing experiment indicated that extensive cleaning of carbonate samples to remove organic material is not necessary.

scholarly journals A High-Performance 14C Accelerator Mass Spectrometry System

Radiocarbon ◽  
2010 ◽  
Vol 52 (2) ◽  
pp. 228-235 ◽  
Author(s):  
M L Roberts ◽  
J R Burton ◽  
K L Elder ◽  
B E Longworth ◽  
C P McIntyre ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Throughput ◽  
Accelerator Mass Spectrometry ◽  
High Performance ◽  
Precision Measurements ◽  
Woods Hole Oceanographic Institution ◽  
Optical Elements ◽  
Mass Spectrometry System ◽  
And Performance ◽  
New System

A new and unique radiocarbon accelerator mass spectrometry (AMS) facility has been constructed at the Woods Hole Oceanographic Institution. The defining characteristic of the new system is its large-gap optical elements that provide a larger-than-standard beam acceptance. Such a system is ideally suited for high-throughput, high-precision measurements of 14C. Details and performance of the new system are presented.

scholarly journals MALDIViz: A Comprehensive Informatics Tool for MALDI-MS Data Visualization and Analysis

2017 ◽  
Vol 22 (10) ◽  
pp. 1246-1252 ◽  
Author(s):  
Kishore Kumar Jagadeesan ◽  
Simon Ekström
Keyword(s):  
Mass Spectrometry ◽  
High Throughput ◽  
High Throughput Screening ◽  
Web Application ◽  
Low Cost ◽  
Maldi Ms ◽  
Ionization Mass ◽  
Label Free ◽  
Label Free Detection ◽  
R Shiny

Recently, mass spectrometry (MS) has emerged as an important tool for high-throughput screening (HTS) providing a direct and label-free detection method, complementing traditional fluorescent and colorimetric methodologies. Among the various MS techniques used for HTS, matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) provides many of the characteristics required for high-throughput analyses, such as low cost, speed, and automation. However, visualization and analysis of the large datasets generated by HTS MALDI-MS can pose significant challenges, especially for multiparametric experiments. The datasets can be generated fast, and the complexity of the experimental data (e.g., screening many different sorbent phases, the sorbent mass, and the load, wash, and elution conditions) makes manual data analysis difficult. To address these challenges, a comprehensive informatics tool called MALDIViz was developed. This tool is an R-Shiny-based web application, accessible independently of the operating system and without the need to install any program locally. It has been designed to facilitate easy analysis and visualization of MALDI-MS datasets, comparison of multiplex experiments, and export of the analysis results to high-quality images.

scholarly journals 14C Ages of Bone Fractions from Armenian Prehistoric Sites

Radiocarbon ◽  
2010 ◽  
Vol 52 (2) ◽  
pp. 569-577 ◽  
Author(s):  
Alexander Cherkinsky ◽  
Christine Chataigner
Keyword(s):  
Mass Spectrometry ◽  
Accelerator Mass Spectrometry ◽  
Organic Material ◽  
Separation Technique ◽  
Middle Paleolithic ◽  
Radiocarbon Dates ◽  
Bone Material ◽  
Younger Age ◽  
Archaeological Artifacts ◽  
Good Agreement

Prehistoric cultures in Armenia are still poorly known; thus, accelerator mass spectrometry (AMS) radiocarbon dates are invaluable in constructing an accurate chronology. Bone samples have been collected from sites representing the Middle Paleolithic, Chalcolithic, and Early Bronze periods. Most of the bone samples are poorly preserved. We describe the separation technique for the extraction of both the bioapatite and collagen fractions. In many cases where the bone had very low organic material content, the collagen fractions yielded a younger age, although the ages of bioapatite fractions were found to be in good agreement with associated archaeological artifacts. In cases where bone was well preserved, both fractions exhibited ages in good agreement with the artifacts. The accuracy of 14C dating of bone material always depends on its degree of preservation, and each case should be carefully evaluated to determine which fraction is less contaminated in order to accurately date a burial event.

scholarly journals The Hvee 14C System at Groningen

Radiocarbon ◽  
1995 ◽  
Vol 37 (2) ◽  
pp. 649-656 ◽  
Author(s):  
Andreas Gottdang ◽  
Dirk J. W. Mous ◽  
Johannes Van Der Plicht
Keyword(s):  
Mass Spectrometry ◽  
High Throughput ◽  
High Voltage ◽  
Accelerator Mass Spectrometry ◽  
Performance Measurements ◽  
System Description ◽  
Accelerator Mass Spectrometer ◽  
And Performance ◽  
High Voltage Engineering ◽  
New Generation

Since May 1994, a new-generation accelerator mass spectrometer (AMS) has been fully operational at the Centre for Isotope Research in Groningen, The Netherlands. The fully automated and high-throughput accelerator mass spectrometry (AMS) system, manufactured by High Voltage Engineering Europa (HVEE) is dedicated to radiocarbon analysis. The HVEE 4130 14C AMS is able to analyze up to 3000 samples per year. The system is characterized by simultaneous transport of all three isotopes (12C, 13C, 14C) and 14C analysis with a precision below 0.5 pMC and a daily stability below 0.5 pMC. We present here a system description together with stability and performance measurements.

High-Throughput and Low-Cost Analysis of Trace Volatile Phthalates in Seafood by Online Coupling of Monolithic Capillary Adsorbent with GC-MS

2016 ◽  
Vol 64 (16) ◽  
pp. 3287-3292 ◽  
Author(s):  
Wimonrut Insuan ◽  
Phatchara Khawmodjod ◽  
Harry J. Whitlow ◽  
Peerapong Soonthondecha ◽  
Fairda Malem ◽  
...  
Keyword(s):  
Cost Analysis ◽  
High Throughput ◽  
Low Cost

scholarly journals High-Throughput Analysis from Complex Matrices: Acoustic Ejection Mass Spectrometry from Phase-Separated Fluid Samples

Metabolites ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 789
Author(s):  
Yuzhu Guo ◽  
Michael Forbush ◽  
Thomas R. Covey ◽  
Lucien Ghislain ◽  
Chang Liu
Keyword(s):  
Mass Spectrometry ◽  
High Throughput ◽  
Complex Matrices ◽  
Two Phase ◽  
High Throughput Analysis ◽  
Throughput Analysis ◽  
Bioanalytical Applications ◽  
Analytical Technology ◽  
Better Than

Acoustic ejection mass spectrometry is a novel high-throughput analytical technology that delivers high reproducibility without carryover observed. It eliminates the chromatography step used to separate analytes from matrix components. Fully-automated liquid–liquid extraction is widely used for sample cleanup, especially in high-throughput applications. We introduce a workflow for direct AEMS analysis from phase-separated liquid samples and explore high-throughput analysis from complex matrices. We demonstrate the quantitative determination of fentanyl from urine using this two-phase AEMS approach, with a LOD lower than 1 ng/mL, quantitation precision of 15%, and accuracy better than ±10% over the range of evaluation (1–100 ng/mL). This workflow offers simplified sample preparation and higher analytical throughput for some bioanalytical applications, in comparison to an LC-MS based approach.

scholarly journals Comparison of Manual and Automated Pretreatment Methods for AMS Radiocarbon Dating of Plant Fossils

Radiocarbon ◽  
1994 ◽  
Vol 36 (3) ◽  
pp. 399-405 ◽  
Author(s):  
Lee-Ann Bradley ◽  
Thomas W. Stafford
Keyword(s):  
Mass Spectrometry ◽  
Accelerator Mass Spectrometry ◽  
Traditional Method ◽  
Radiocarbon Dating ◽  
Automated System ◽  
Sample Material ◽  
Ams Radiocarbon Dating ◽  
Manual Method ◽  
Plant Fossils

A new automated pretreatment system for the preparation of materials submitted for accelerator mass spectrometry (AMS) analysis is less time-consuming and results in a higher sample yield. The new procedure was tested using two groups of plant fossils: one group was pretreated using the traditional method, and the second, using the automated pretreatment apparatus. We compared the time it took to complete the procedure and the amount of sample material remaining. The automated pretreatment apparatus proved to be more than three times faster and, in most cases, produced a higher yield. We also observed a darker discoloration of the KOH solutions, indicating that the automated system is more thorough in removing humates from the specimen compared to the manual method.

Radiocarbon dating by accelerator mass spectrometry: some recent results and applications

1987 ◽  
Vol 323 (1569) ◽  
pp. 57-73 ◽  
Keyword(s):  
Mass Spectrometry ◽  
Accelerator Mass Spectrometry ◽  
Radiocarbon Dating ◽  
Chemical Compounds ◽  
Environmental Research ◽  
Specific Chemical ◽  
Archaeological Material ◽  
Comparable Accuracy ◽  
Different Sources ◽  
Better Than

14 C differs from other nuclides measured by accelerator mass spectrometry (AMS) in that an extensive database of dates already exists, AMS dates should therefore have comparable accuracy, and the measurement of isotopic ratios to better than 1 % , which was an important technical goal, has been reached. The main advantage of being able to date samples 1000 times smaller than previously lies in the extra selectivity that can be employed. This is reflected in the results and applications. Selection can apply at several levels; from objects th at formerly contained too little carbon, to the choice of archaeological material, to the extraction of specific chemical compounds from a complex environmental sample. This is particularly useful in removing uncertainty regarding the validity of a date, since a given sample may comprise carbon atoms from different sources each with their own 14 C ‘age’. Examples from archaeological and environmental research illustrating these points are given. 14 C dating by AMS differs from conventional radiocarbon dating by having the potential to measure much lower levels of 14 C, and therefore should double the time span of the method. This potential has not yet been realized because of sample contamination effects, and work in progress to reduce these is described.

INTER-UNIVERSITY ACCELERATOR CENTRE, NEW DELHI (IUACD) RADIOCARBON DATE LIST I

Radiocarbon ◽  
2020 ◽  
Vol 62 (5) ◽  
pp. e1-e13
Author(s):  
Rajveer Sharma ◽  
Pankaj Kumar ◽  
Sunil Ojha ◽  
Satinath Gargari ◽  
Sundeep Chopra
Keyword(s):  
Mass Spectrometry ◽  
Accelerator Mass Spectrometry ◽  
Radiocarbon Dating ◽  
Background Level ◽  
New Delhi ◽  
Handling System ◽  
Carbon Sample ◽  
New Facility ◽  
Pelletron Accelerator ◽  
Better Than

ABSTRACTA new facility for radiocarbon dating by accelerator mass spectrometry (AMS) was established in early 2015 at the Inter-University Accelerator Centre in New Delhi, India. The facility uses a 500 kV National Electrostatic Corporation (NEC) Pelletron accelerator for AMS measurements on graphite produced using the automated graphitization equipment (AGE) interfaced with an elemental analyzer and the carbonate handling system (CHS). A precision of better than 1‰ in the ratio of 14C/12C for the modern carbon sample and the background level of 1 × 10–15 from dead carbon sample has been achieved. This is the first dedicated accelerator of India only for AMS activities. This AMS system has the capabilities to perform 10Be and 26Al measurements as well.

New Chronometric Dates for the Puquios of Nasca, Peru

1995 ◽  
Vol 6 (1) ◽  
pp. 56-69 ◽  
Author(s):  
Persis B. Clarkson ◽  
Ronald I. Dorn
Keyword(s):  
Mass Spectrometry ◽  
Accelerator Mass Spectrometry ◽  
Organic Material ◽  
Settlement Pattern ◽  
Colonial Period ◽  
South Coast ◽  
Spanish Conquest ◽  
Rock Varnish ◽  
Available Information

Numeric age assessments of organic material encapsulated by rock varnish present on stone lintels of two “puquios” in the Nasca region of the south coast of Peru indicate a Precolumbian age. Accelerator mass spectrometry radiocarbon analyses at the Isotrace Laboratory revealed ages of cal A. D. 560(620)650 and cal A. D. 600(640)660 (1 sigma). These calibrated measurements are considered to be appropriate in the context of the archaeological settlement pattern data for the region. As well, the written documents of the colonial period neither confirm nor deny the presence of the puquios. Three assumptions are inherent in the acceptance of these dates: (1) AMS 14C dating and its application to rock varnish yield reliable results, (2) sample contamination can be recognized, and (3) determination of the age of the puquios rests upon testable available information; ex silentio arguments about the presence or absence of the puquios in the Nasca region before the Spanish conquest are inadequate for the resolution of the question.

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