Lexical influences on nonword repetition

1995 ◽  
Vol 16 (2) ◽  
pp. 211-222 ◽  
Author(s):  
Christine A. Dollaghan ◽  
Maureen E. Biber ◽  
Thomas F. Campbell
Keyword(s):  
Memory Span ◽  
Nonword Repetition ◽  
Long Term Memory ◽  
Acoustic Cues ◽  
Lexical Information ◽  
Immediate Memory ◽  
Normally Achieving ◽  
Lexical Sequences

ABSTRACTThe present investigation explores the hypothesis that lexical information influences performance on nonword repetition tasks. The subjects – 30 normally achieving, school-aged boys – repeated multisyllabic nonword pairs, constructed to vary only in the lexicality of their constituent stressed syllables. Nonwords with stressed syllables corresponding to real words were repeated significantly more accurately than nonwords with non-lexical stressed syllables; stressed syllable lexicality primarily influenced repetition of the remaining unstressed syllables. Subsequent analyses revealed that the overwhelming majority of repetition errors operated to transform non-lexical sequences into real words, even when doing so violated both strong acoustic cues and articulatory ease. We conclude that lexical long-term memory information intrudes on nonword repetition performance, including stimuli that are within the limits of immediate memory span. These results suggest a number of caveats concerning the construction and interpretation of nonword repetition tasks and raise questions about the role of such tasks in assessing phonological working memory.

The role of attention during retrieval in working-memory span: A dual-task study

2009 ◽  
Vol 62 (4) ◽  
pp. 733-745 ◽  
Author(s):  
M. Karl Healey ◽  
Akira Miyake
Keyword(s):  
Task Performance ◽  
Divided Attention ◽  
Secondary Task ◽  
Memory Span ◽  
Long Term Memory ◽  
Term Memory ◽  
Operation Span ◽  
Target Words

We tested the hypothesis that retrieving target words in operation span (OSpan) involves attention-demanding processes. Participants completed the standard OSpan task and a modified version in which all equations preceded all target words. Recall took place under either full attention or easy versus hard divided-attention conditions. Recall suffered under divided attention with the recall decrement being greater for the hard secondary task. Moreover, secondary-task performance was disrupted more by the standard OSpan task than by the modified version with the hard secondary task showing the larger decrement. Finally, the time taken to start recalling the first word was considerably longer for the standard version than for the modified version. These results are consistent with the proposal that successful OSpan task performance in part involves the attention-demanding retrieval of targets from long-term memory.

A link between role of two prefrontal areas in immediate memory and in long-term memory consolidation

2007 ◽  
Vol 88 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Luciana A. Izquierdo ◽  
Daniela M. Barros ◽  
Jaderson Costa da Costa ◽  
Cristiane Furini ◽  
Carolina Zinn ◽  
...  
Keyword(s):  
Memory Consolidation ◽  
Long Term Memory ◽  
Term Memory ◽  
Immediate Memory

The role of long-term memory mechanisms in memory span

1995 ◽  
Vol 86 (4) ◽  
pp. 527-536 ◽  
Author(s):  
Charles Hulme ◽  
Steven Roodenrys ◽  
Gordon Brown ◽  
Robin Mercer
Keyword(s):  
Memory Span ◽  
Long Term Memory ◽  
Term Memory

Effects of Generation on Immediate Memory Span and Delayed Unexpected Free Recall

1994 ◽  
Vol 47 (3) ◽  
pp. 781-804 ◽  
Author(s):  
Richard Schweickert ◽  
Mark A. McDaniel ◽  
Gregory Riegler
Keyword(s):  
Free Recall ◽  
Word Length ◽  
Memory Span ◽  
Harmful Effect ◽  
Speaking Rate ◽  
Long Term Memory ◽  
Term Memory ◽  
Immediate Memory ◽  
Multiplicative Effects

We investigated the effects of generating words from fragments on pronunciation time, on immediate memory span, and on delayed free recall. Subjects read long words and short words aloud or generated them from strings with missing letters. Word-length and generation condition had multiplicative effects on speaking rate, as expected if each affected a separate process regulating the rate. We replicated the standard finding that span is smaller for longer words. Generation improved delayed free recall, indicating that relatively brief presentation times are adequate to produce a generation effect. Although generation improved long-term memory for the words, memory span was shorter for the words that were generated. The harmful effect of generation on span appears to be due to its slowing of speaking rate.

The role of PKMζ in the maintenance of long-term memory: a review

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Hamish Patel ◽  
Reza Zamani
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Long Term Potentiation ◽  
Global Memory ◽  
Long Term Memory ◽  
Compensatory Mechanism ◽  
Term Memory ◽  
Kinase C

Abstract Long-term memories are thought to be stored in neurones and synapses that undergo physical changes, such as long-term potentiation (LTP), and these changes can be maintained for long periods of time. A candidate enzyme for the maintenance of LTP is protein kinase M zeta (PKMζ), a constitutively active protein kinase C isoform that is elevated during LTP and long-term memory maintenance. This paper reviews the evidence and controversies surrounding the role of PKMζ in the maintenance of long-term memory. PKMζ maintains synaptic potentiation by preventing AMPA receptor endocytosis and promoting stabilisation of dendritic spine growth. Inhibition of PKMζ, with zeta-inhibitory peptide (ZIP), can reverse LTP and impair established long-term memories. However, a deficit of memory retrieval cannot be ruled out. Furthermore, ZIP, and in high enough doses the control peptide scrambled ZIP, was recently shown to be neurotoxic, which may explain some of the effects of ZIP on memory impairment. PKMζ knockout mice show normal learning and memory. However, this is likely due to compensation by protein-kinase C iota/lambda (PKCι/λ), which is normally responsible for induction of LTP. It is not clear how, or if, this compensatory mechanism is activated under normal conditions. Future research should utilise inducible PKMζ knockdown in adult rodents to investigate whether PKMζ maintains memory in specific parts of the brain, or if it represents a global memory maintenance molecule. These insights may inform future therapeutic targets for disorders of memory loss.

scholarly journals Enhanced Antimycobacterial Response to RecombinantMycobacterium bovis BCG Expressing Latency-Associated Peptide

2001 ◽  
Vol 69 (11) ◽  
pp. 6676-6682 ◽  
Author(s):  
Ben G. Marshall ◽  
Arun Wangoo ◽  
Peadar O'Gaora ◽  
H. Terry Cook ◽  
Rory J. Shaw ◽  
...  
Keyword(s):  
Detrimental Effect ◽  
Transforming Growth Factor ◽  
Initial Response ◽  
Transforming Growth Factor Β ◽  
Mycobacterial Infection ◽  
Acute Stage ◽  
Long Term Memory ◽  
Memory Response

ABSTRACT With a view to exploring the role of transforming growth factor β (TGF-β) during mycobacterial infection, recombinant clones of bacillus Calmette-Guérin (BCG) were engineered to express the natural antagonist of TGF-β, latency-activated peptide (LAP). Induction of TGF-β activity was reduced when macrophages were infected with BCG expressing the LAP construct (LAP-BCG). There was a significant reduction in the growth of LAP-BCG in comparison to that of control BCG following intravenous infection in a mouse model. The enhanced control of mycobacterial replication was associated with an increase in the production of gamma interferon by splenocytes challenged during the acute stage of infection but with a diminished recall response assessed after 13 weeks. Organ weight and hydroxyproline content, representing tissue pathology, were also lower in mice infected with LAP-BCG. The results are consistent with the hypothesis that TGF-β has a detrimental effect on mycobacterial immunity. While a reduction in TGF-β activity augments the initial response to BCG vaccination, early bacterial clearance may adversely affect the induction of a long-term memory response by LAP-BCG.

scholarly journals HYPERMNESIA EUPHORIA OR ANY OTHER DESIRABLE FROM THE POINT OF VIEW OF THE CONSUMER, A PSYCHOTROPIC EFFECT - FIRST AND LEADING ELEMENT IN THE OCCURRENCE AND PRESERVATION OF THE BODY’S DEPENDENCE ON PSYCHOACTIVE FACTORS

2017 ◽  
Vol 9 (3) ◽  
pp. 40-46
Author(s):  
D G Baitubayev ◽  
M D Baitubayeva
Keyword(s):  
Substance Dependence ◽  
Point Of View ◽  
The Body ◽  
Long Term Memory ◽  
Vegetative Nervous System ◽  
Term Memory ◽  
Psychotropic Effect

The work shows the role of the vegetative nervous system (VNS) in the functioning of long-term memory, identity mechanisms of long-term memory in the human evolutionary adaptation and substance dependence. It is shown that, depending on the substance of the body are states like pro- gressive adaptation, that the bodycondition, depending on the chemical and psychogenic psychoactive- factors state of the same circle. It proposed the creation of a branch of medicine that combines study of the dependence of the organism, both on the chemical and psychoactive psychogenic factors. Given the classification of psychoactive factors.Onomastics formulated definitions of terminology changes and additions to be used in a new branch of medicine. Proposed allocation of the International Classifica- tion of diseases separate chapter for the classification of states like progressive adaptation of the body depending on psychoactive factors.

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