Effects of aculeacin A and papulacandin B on Candida albicans
1984 ◽
Vol 42
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pp. 706-707
Keyword(s):
Aculeacin A1 and papulacandin B2 are closely related antimycotic agents that interfere with the synthesis of alkalai-insoluble β 1-3 glucan in the cell wall of Candida albicans, Saccharomyces cerevisiae and Geotrichum lactis. The chemical structures of both agents contain a long-chain fatty acid, and both agents are strongly inhibitory to C. albicans and some other fungi while having negligible activity against bacteria or protozoa. Earlier studies involving light microscopy of aculeacin A treated cells revealed rounded, distorted cells aggregated in clumps. The sole TEM micrograph of aculeacin A treated cells showed invaginations and globular bodies associated with plasma membranes.
2019 ◽
Vol 18
(5)
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pp. 1199-1206
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1988 ◽
Vol 177
(1)
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pp. 207-211
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Keyword(s):
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1994 ◽
Vol 13
(23)
◽
pp. 5531-5538
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Keyword(s):
2005 ◽
Vol 177
(1)
◽
pp. 207-211
Keyword(s):
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2003 ◽
Vol 269
(2)
◽
pp. 290-298
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